Sarcoplasmic reticulum Ca-ATPase
Ca++ Uptake and ATPase of Human Sarcoplasmic Reticulum
... ATPase activity of grana obtained from human white muscle was only slightly inhibited by sodium azide; purified grana activity showed little or no inhibition by azide Table III.. The ATP[r] ...
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Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation
... In vivo hemodynamic assessment. The procedure was as de- scribed previously (39). In brief, age-matched transgenic and control littermates were used. Animals were anesthetized with a mixture of ketamine (90–110 mg/kg) ...
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Ca2+ ATPase activity and Ca2+ uptake by sarcoplasmic reticulum in fish heart: effects of thermal acclimation
... acclimated carp ventricle agrees with the reduced cardiac activity in cold-acclimated crucian carp, expressed as a long relaxation time, a slow heart rate and low myosin-ATPase activity of the heart (Matikainen ...
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Localisation of intracellular calcium stores in the striated muscles of the jellyfish Polyorchis penicillatus: possible involvement in excitation–contraction coupling
... indeed sarcoplasmic reticulum and possibly involved in excitation–contraction coupling in swimming muscle cells, we used a cytochemical method (Ando et ...of Ca 2+ -ATPase activity in these ...
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Activity of Ca(2+),Mg(2+)-ATPase of sarcoplasmic reticulum and contraction strength of the frog skeletal muscles under the effect of organophosphorus insecticides
... досліджень показали концентраційнозалежне пригнічення скоротливої активності СМ за дії піриміфосметилу, діазинону та хлорпірифосу. Причому зниження силової продуктивності [r] ...
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The effect of chlorpyrifos upon ATPase activity of sarcoplasmic reticulum and biomechanics of skeletal muscle contraction
... tivity may result from permeation of SR membrane due to intensive lipid peroxidation [17]. It may be explained by the capacity of these substances to en- ter cell through the plasma membrane and disrupt intracellular ...
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Ca(2+)transport by the sarcoplasmic reticulum Ca(2+) ATPase in sea cucumber (Ludwigothurea grisea) muscle
... cucumber smooth muscle, rabbit skeletal muscle and dog cardiac muscle were analysed by SDS–PAGE and silver staining and revealed a major band at 110 kDa (Landeira- Fernandez et al., 2000b). When western blots of these ...
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Comparative studies on the sarcoplasmic reticulum of fish muscle
... in cold adapted fish to positive values in more warm adapted species (Pig. 5:6). Mechanistic interpretations of these results is made difficult by a lack of information concerning the detailed kinetics of the reaction. ...
232
Cardiac Adaptation To Chronic Blockade Of Voltage-Gated, L-Type Calcium Channels In The Sarcolemma
... Depolarization-induced Ca 2+ influx into cardiomyocytes via L-type Ca 2+ channels (dihydropyridine receptor, DHPR) results in Ca 2+ -induced Ca 2+ release from sarcoplasmic ...
240
Biphasic decay of the Ca transient results from increased sarcoplasmic reticulum Ca leak
... cytosolic Ca concentration (Ca transient) with most of this calcium released from the sarcoplasmic reticulum (SR) through the ryanodine receptor (RyR) (see Bers, 2002 and Eisner et ...release ...
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GENETICS AND MOLECULAR BIOLOGY AND PIG MEAT QUALITY IMPROVEMENT
... short peptide representing a functional domain of the dihydropyridin receptor (DHPR). DHPR serves as voltage sensor for incoming action potentials and is located directly opposite the calcium release channels. Calcium ...
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Altered sarcoplasmic reticulum Ca2(+) ATPase gene expression in the human ventricle during end stage heart failure
... A decrease in the myocardial level of the mRNA encoding the Ca2(+)-ATPase of the sarcoplasmic reticulum (SR) has been recently reported during experimental cardiac hypertrophy and failure. To ...
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Abstract We simulate elementary calcium release events (sparks) in a single calcium release unit in
... reticulum), a cluster (9x9) RyR-channels and a dyadic space. RyR’s square cluster is located in jSR membrane. T-tubule membrane contains potential activated L-type calcium channels. Released from jSR calcium ...
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chapt08_lecture.ppt
... Beneath the sarcolemma of a muscle fiber lies the sarcoplasmic reticulum (endoplasmic reticulum), which is associated with transverse (T) tubules (invaginations of the sarcolemma[r] ...
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Ca 2+ leakage out of the sarcoplasmic reticulum is increased in type I skeletal muscle fibres in aged humans
... increased Ca 2+ leakage out of the SR in the type I fibres of Old human subjects relative to that in type I fibres of Young subjects, ii) that the leakage occurs primarily through the RyRs, and iii) that strong ...
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Calcium transport by skeletal muscle sarcoplasmic reticulum in the hypothyroid rat
... by sarcoplasmic reticulum has reached maximum levels, results in a depression in the rate of calcium ...in ATPase activity of the sarcoplasmic reticulum to account for the low calcium ...
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The influence of PKA treatment on the Ca2+ activation of force generation by trout cardiac muscle
... Western blotting was used to identify cTnI, cTnT and cMyBP-C. For western blot analysis, native trout cardiac muscle proteins were separated on an SDS-PAGE gel. The SDS-PAGE gel was then transferred onto Hybond-P PVDF ...
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Temperature perturbation studies of sarcoplasmic reticulum from malignant hyperthermia pig muscle
... susceptible group (MHX). At 25 degrees C, calcium binding was lower for MHS than for controls and MHX. As temperature was increased by 2 degrees C jumps, calcium binding decreased in all sarcoplasmic ...
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Ma2/d promotes myonuclear positioning and association with the sarcoplasmic reticulum
... Fully differentiated skeletal muscle fibers are multinucleated, elongated cells with highly ordered cytoplasm, essential for efficient muscle contraction and organismal movement. Muscle nuclei are positioned evenly along ...
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Regulation of cardiac contractility in a cold stenothermal fish, the burbot Lota lota L
... myofibrillar ATPase is a significant determinant of contraction rate (Barany, ...myofibrillar ATPase activity was higher in atrial than ventricular muscle and explains, to a large extent, the faster ...
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