Sarcoplasmic reticulum Ca2+–ATPase (SERCA)
Thyroid hormone improves function and Ca2+ handling in pressure overload hypertrophy Association with increased sarcoplasmic reticulum Ca2+ ATPase and alpha myosin heavy chain in rat hearts
... hearts. Sarcoplasmic reticulum Ca2+-ATPase (SERCA), phospholamban, and alpha- and beta-myosin heavy chain (MHC) proteins were assayed in homogenates of myocytes isolated from the same ...
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Sarcoplasmic reticulum Ca2+ ATPase (SERCA) activity during the transition to endothermy in an altricial bird
... on SERCA activity (Swanson et ...on SERCA activity in either the pectoralis muscle or the heart ...and SERCA activity when considering all ages of the control group, this correlation may be spurious ...
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Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation
... calcium pump of the sarcolemma (1). SERCA2 is a member of the P-type ion-motive ATPases that form a phosphoprotein in- termediate during ion translocation. Five distinct SERCA iso- forms that are encoded by three ...
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Altered sarcoplasmic reticulum Ca2(+) ATPase gene expression in the human ventricle during end stage heart failure
... SR Ca2(+)-ATPase cDNA ...the Ca2(+)-ATPase relative to both the 18S ribosomal RNA and the myosin heavy chain mRNA in LV specimens of patients with heart failure compared to controls (-48%, P ...
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Differences in locomotor performance between individuals: importance of parvalbumin, calcium handling and metabolism
... Ryanodine receptor RyR and sarcoplasmic reticulum Ca2+-ATPase 1 SERCA1 mRNA concentrations were significantly increased in high sustained performance fish, while parvalbumin 2, dihydropy[r] ...
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Changes of SERCA activity have only modest effects on sarcoplasmic reticulum Ca2+ content in rat ventricular myocytes
... of SERCA activity would be expected to increase SR Ca 2+ content and thereby increase cardiac ...of SERCA activity are involved in both normal and pathological changes of cardiac Ca 2+ ...handling. ...
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Adaptive thermogenesis in hummingbirds
... Although birds are the sarcoplasmic reticulum Ca2+-ATPase, uncoupled from endothermic vertebrates, sharing with mammals placental ATP synthesis, is one mechanism whereby chemi-osmotic ma[r] ...
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Molecular cloning and characterization of a Ca2+ + Mg2+ dependent adenosine triphosphatase from rat cardiac sarcoplasmic reticulum Regulation of its expression by pressure overload and developmental stage
... cardiac Ca2+ + Mg2+-dependent ATPase (Ca2+-ATPase) in sarcoplasmic reticulum (SR), we isolated cDNA (pHA6) encoding a Ca2+-ATPase of rat cardiac ...
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Ca2+ ATPase activity and Ca2+ uptake by sarcoplasmic reticulum in fish heart: effects of thermal acclimation
... that thermal acclimation may alter the excitation–contraction coupling process of the fish heart. Morphometric analyses of perch heart suggest that SR is better developed in cold- acclimated than in warm-acclimated fish ...
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Phospholamban mediated stimulation of Ca2+ uptake in sarcoplasmic reticulum from normal and failing hearts
... transporting ATPase from 0.53 microM [( Ca2+]) to 0.29 microM [( Ca2+]), without affecting Vmax or ...microM Ca2+, stimulation was 1.93-fold in sarcoplasmic reticulum prepared ...
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Cardiac Adaptation To Chronic Blockade Of Voltage-Gated, L-Type Calcium Channels In The Sarcolemma
... Ca 2+ influx into cardiomyocytes via L-type, dihydropyridine receptor (DHPR)- Ca 2+ channels, is crucial for ryanodine receptor (RyR2)-mediated sarcoplasmic reticulum (SR) Ca 2+ release and muscle ...
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Contractile properties of atrial and ventricular myocardium of the heart of rainbow trout oncorhynchus mykiss: effects of thermal acclimation
... Cellular processes that are responsible for the initiation of cardiac contraction need a finite time to recover from inactivation. Mechanical restitution describes this recovery process at short diastolic intervals and ...
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Investigation of the mechanisms of Angelica dahurica root extract induced vasorelaxation in isolated rat aortic rings
... Effects of ADE on intracellular Ca2+ release: In order to investigate the effects of ADE on intracellular Ca2+ release from sarcoplasmic reticulum SR-induced contraction via specific ino[r] ...
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How well do muscle biomechanics predict whole animal locomotor performance? The role of Ca2+ handling
... other SERCA isoforms partially compensated for the reduction in SERCA2 activity, and that store depletion did not reduce force production over the time frame of ...ultimately SERCA activity is essential in ...
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Towards understanding EC coupling protein expression with age
... "Molecular cloning of cDNA encoding the Ca2+ release channel ryanodine receptor of rabbit cardiac muscle sarcoplasmic reticulum." The Journal of biological chemistry 26523: 13472-13483..[r] ...
261
The effect of the aluminum chloride – quercetin complex on Ca(2+),Mg(2+)-ATPase activity and contraction dynamic properties of muscle tibialis anterior from Rana temporaria
... Muscle fiber contraction should not be viewed as a uniform and smooth process. The timeframes of single contractions represent a synchronized process of interaction between components of a sarcomere in a neatly ...
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The influence of PKA treatment on the Ca2+ activation of force generation by trout cardiac muscle
... In mammalian hearts the accelerated rate of force development with PKA treatment is caused by the phosphorylation of cMyBP- C (Stelzer et al., 2007). This is thought to be in response to changes in the interaction ...
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Selenoprotein W redox-regulated Ca 2+ channels correlate with selenium deficiency-induced muscles Ca 2+ leak
... against SERCA (1:1000, Immunoway Biotechnology Company, USA) and SelW (made by our lab) followed by a horseradish peroxidase (HRP)-conjugated secondary antibody against rabbit IgG (1:3000, Santa Cruz ...
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SERCA2a: its role in the development of heart failure and as a potential therapeutic target
... Abstract: The complexity of heart physiology has delayed the implementation of efficient, feasible, and safe therapies to fight against heart diseases for many years. As knowledge of the precise mechanisms governing ...
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Expression of SERCA and phospholamban in rainbow trout (Oncorhynchus mykiss) heart: comparison of atrial and ventricular tissue and effects of thermal acclimation
... cardiac SERCA – recognized by the antibody – is likely to represent ...clarify SERCA protein function and its physiological significance in thermally acclimated fish ...
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