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SARS-CoV-2

Identification of a low pathogenicity clade of SARS-CoV-2

Identification of a low pathogenicity clade of SARS-CoV-2

... by SARS-CoV-2 exceeded 5 million as of May 21, ...investigated SARS-CoV-2 strains specific to Singapore in this study to identify a clade with low ...

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Proposed drug interventions for SARS CoV 2 infection

Proposed drug interventions for SARS CoV 2 infection

... Corona viruses attachment starts with interaction of the S protein with the surface receptors, the receptor binding domains (RBD) are loacted on S1 and fusion sequence on S2. There are different receptors like DPP4, ...

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The Frequency of G614 SARS-CoV-2 Variant in India

The Frequency of G614 SARS-CoV-2 Variant in India

... as SARS-CoV-2 to distinguish it from the SARS- CoV strain of the 2002 outbreak ...of SARS-CoV-2 is of special interest because the variant containing this mutation ...

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The Conceptual Framework for SARS-CoV-2 Related Lymphopenia

The Conceptual Framework for SARS-CoV-2 Related Lymphopenia

... This cytokine profile indicates a rapid recruitment and increased trafficking of the monocyte- macrophage lineage into the lung very early in the infection process. The immune cell infiltration into the lower respiratory ...

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Model of trigger mechanisms of SARS CoV-2 infections

Model of trigger mechanisms of SARS CoV-2 infections

... by SARS-CoV-2 from published articles related to ...the SARS-CoV-2 S protein reaches cells containing ACE2 receptors, being mainly the upper respiratory tract, followed by the ...

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SARS-CoV-2 virion stabilization by Zn binding

SARS-CoV-2 virion stabilization by Zn binding

... in SARS-CoV-2 by genes ORF7a and ORF8 are likely involved in zinc binding and in interactions with cellular antigens activated by extensive disulfide ...

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The Structure of the Membrane Protein of SARS-CoV-2 Resembles the Sugar Transporter semiSWEET

The Structure of the Membrane Protein of SARS-CoV-2 Resembles the Sugar Transporter semiSWEET

... including SARS-COV (Yang et ...that SARS coronavirus enters islets and damages islets causing acute diabetes (Yang et ...of SARS-CoV-2 spike glycoprotein predicts that it can ...

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Running Title: Microevolution of SARS-CoV-2 Key words: SARS-CoV-2, COVID-19, genome-wide mutations,

Running Title: Microevolution of SARS-CoV-2 Key words: SARS-CoV-2, COVID-19, genome-wide mutations,

... 3,608 SARS- CoV-2 RNA-genomes short-listed from a total 5,485 whole genome sequences deposited in GenBank till 4 June 2020 using a download filter that eliminated all incomplete/gapped ...existing ...

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An overview of SARS‐CoV‐2 and animal infection

An overview of SARS‐CoV‐2 and animal infection

... SARSCoV2 is a novel betacoronavirus (β-coronavirus) belongs to the subgenus sarbecovirus of the Coronaviridae ...between SARSCoV2 and ...

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Collective Clustering Dynamics of SARS-COV-2 Particles

Collective Clustering Dynamics of SARS-COV-2 Particles

... whether SARS- Cov-2 particles, responsible for COVID-19, display collective clustering ...of SARS-Cov-2 particles emerging from the surface of cultured cells, we describe single ...

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Risk of Human-to-Wildlife Transmission of SARS-CoV-2

Risk of Human-to-Wildlife Transmission of SARS-CoV-2

... In humans, COVID-19 symptoms range very widely, including mild respiratory problems, gastro-intestinal issues, headaches, severe acute respiratory syndrome, and no symptoms at all [4, 32]. The infection fatality rate of ...

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Virtual Screening and Molecular Dynamics Study on Blockage of Key Drug Targets as Treatment for COVID-19 caused by SARS-CoV-2

Virtual Screening and Molecular Dynamics Study on Blockage of Key Drug Targets as Treatment for COVID-19 caused by SARS-CoV-2

... coronavirus 2 (SARS-CoV-2, named by ICTV, previously known as 2019-nCoV by ...1 SARS-CoV-2 has caused more than 77,000 people infected ...

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SARS-CoV-2, COVID 19 Useful information

SARS-CoV-2, COVID 19 Useful information

... by SARS-CoV-2 is constantly evolving, so it is necessary to stay up to date on the results of developing clinical trials and real-world experience to match therapy for the greatest benefit of ...

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Structural Similarity Analysis of Spike Proteins of SARS-CoV-2 and Other SARS-related Coronaviruses

Structural Similarity Analysis of Spike Proteins of SARS-CoV-2 and Other SARS-related Coronaviruses

... with SARS- CoV-2, with 96% identity at the whole-genome level ...between SARS-CoV-2 and other SARS-related other ...of SARS-CoV-2 was found to be very ...

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Repurposing antivirals as potential treatments for SARS-CoV-2: From SARS to COVID-19

Repurposing antivirals as potential treatments for SARS-CoV-2: From SARS to COVID-19

... first SARS outbreak in ...on SARS-CoV replication appeared since 2003 (Cinatl et ...inhibit SARS- CoV replication (Chen et ...of SARS-CoV replication (Koren et ...of ...

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Genomic characterization and phylogenetic analysis of SARS-CoV-2 in Asia

Genomic characterization and phylogenetic analysis of SARS-CoV-2 in Asia

... coronavirus 2 (SARS-CoV-2) is a Betacoronavirus, subgenus Sarbecovirus is a novel coronavirus that initially detected in Wuhan city of Hubei province in China in the late December of 2019 ...

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SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional Convergence

SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional Convergence

... of SARS-CoV-2 ORF8 predicts an N-terminal signal peptide located within amino acids 2-16 with 5-13 stretch having high hydrophobicity, a feature resonant with 6-15 hydrophobic core signal ...

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CRISPR-Based Assays for Rapid Detection of SARS-CoV-2

CRISPR-Based Assays for Rapid Detection of SARS-CoV-2

... of SARS-CoV-2 crRNAs were designed to target nucleocapsid phosphoprotein encoding N ...of SARS-CoV-2 for detection within 30 ...of SARS-CoV-2 cDNA to 1 nM ...

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Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs

Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs

... newest SARS-CoV-2 (the causative agent of COVID-19) lead to severe and deadly diseases with mortality rates ranging between ~1 to 35% depending on factors such as age and pre-existing ...anti- ...

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Anosmia and Ageusia as Initial or Unique Symptoms after SARS-COV-2 Virus Infection (Review article)

Anosmia and Ageusia as Initial or Unique Symptoms after SARS-COV-2 Virus Infection (Review article)

... 40. Chen BP, Kuziel WA, Lane TE. Lack of CCR2 results in increased mortality and impaired leukocyte activation and trafficking following infection of the central nervous system with a neurotropic coronavirus. J Immunol ...

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