SARS-CoV-2 (COVID-19)
Running Title: Microevolution of SARS-CoV-2 Key words: SARS-CoV-2, COVID-19, genome-wide mutations,
... agent: SARS coronavirus 2, abbreviated as SARS-CoV-2; see Green, 2020) that has spread to 216 countries, infecting 14,562,550 people, and killing 607,781 as of 22 July 2020 ...of ...
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Identification of Pharmacophoric features and novel compounds for inhibition of SARS-Cov-2 Main Protease
... 4. Conclusion: Considering the critical situation being faced by humanity in present scenario due to COVID-19 and unavailability of approved drugs poses a great difficulty. As per the reports, HIV-1 ...
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Anosmia and Ageusia as Initial or Unique Symptoms after SARS-COV-2 Virus Infection (Review article)
... between COVID-19 and altered olfactory and taste functions, although smell seems to be more affected than ...and CoV-2 are consistent with case reports describing a patient with SARS ...
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SARS-CoV-2/COVID-19: Viral Genomics, Epidemiology, Vaccines, and Therapeutic Interventions
... of SARS-CoV-2 is not surprising as coronaviruses habour error-prone RNA-dependent RNA polymerases which make the occurrence of mutations and recombination events rather frequent ...correlate ...
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SARS-CoV-2 (COVID-19) Outbreak a Global Pandemic Challenge
... The 2019 novel coronavirus (previously 2019-nCoV) or coronavirus infectious disease 2019 (COVID-19) outbreak has been summarized as on June 05, 2020. COVID-19 is a highly transmittable and ...
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An Updated Primer on SARS-CoV-2 and the Evolving Covid-19 Pandemic
... virus 2 (SARS- CoV-2) originated in the city of Wuhan, China in late ...the Covid-19 pandemic has become the most dangerous global infectious disease of the 21 st century ...
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COVID-19 Pandemic: Insights into Structure, Function, and hACE2 Receptor Recognition by SARS-CoV-2
... the SARS-CoV-2 structure, illustration of virus is adapted from “Desiree Ho, Innovative Genomics Institute”, available at ...the SARS-CoV-2 spike protein. (D) Schematic of ...
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<p>Alteration of Liver Biomarkers in Patients with SARS-CoV-2 (COVID-19)</p>
... 1 COVID-19 is caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2 ...2,3 SARS-CoV-2 is classi fi ed as a single-stranded and positive-sense RNA ...
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Repurposing antivirals as potential treatments for SARS-CoV-2: From SARS to COVID-19
... of COVID-19, the lopinavir/ritonavir combination has been used as an experimental therapy in several cases, and some clinical trials are under development, but the outcomes remain ...hospital ...
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Lysosomotropic active compounds— hidden protection against COVID-19 / SARS-CoV-2 infection?
... of SARS-CoV-2 infections, as well as influenza A infections and cytokine release syndrome (CRS) triggered by bacterial or viral ...the COVID-19 ...
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The main protease of SARS-CoV-2 as therapeutic target to development specific drugs to treat COVID-19
... 2020 COVID-19 gained pandemic status ...coronavirus 2 (SARS-CoV-2) by the Coronavirus Study Group and the disease was named coronavirus disease 2019 (COVID-19) by ...
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Lessons for SARS-CoV-2 study (COVID-19 disease) from its exosome relatives
... that SARS-CoV-2 may also present tetraspanins and other host molecules on its surface, therefore standard, single marker isolation approaches might not be ...
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Computational strategies to combat COVID-19: Useful tools to accelerate SARS-CoV-2 and Coronavirus research
... Besides qRT-PCR, genome analysis plays a crucial role in public health responses, including epidemiolog- ical efforts to track and contain the outbreak (see Sec- tion Tracking, epidemiology and evolution). The genome ...
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Short note Understanding the origin of ‘BatCoVRaTG13’, a virus closest to SARS-CoV-2
... of SARS-CoV-2 1 ...or SARS-CoV-2 1 ...from SARS-CoV-2 (also known as 2019-nCoV) isolated from early patients were submitted 1 ...of ...
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SARS-CoV-2, COVID 19 Useful information
... by SARS-CoV-2 is constantly evolving, so it is necessary to stay up to date on the results of developing clinical trials and real-world experience to match therapy for the greatest benefit of ...
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SARS-CoV-2 and Covid-19 Immunopathogenesis
... hallmarks of acute distress respiratory syndrome of Covid-19. 5) Endothelial activation, fluid leakage, and immune cell.. 473.[r] ...
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Bioaerosol Size Effect in COVID-19 Transmission
... coronavirus 2 (SARS-CoV-2), constitutes an unprecedent challenge in recent history to the international public health, educational, and trade systems, affecting the overall wellbeing of human ...
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COVID-19 related organ dysfunction and management strategies on the intensive care unit
... in COVID-19 [107,108]. Initial rapid SARS-CoV-2 replication results in activation of lymphocytes (natural killer, T-helper and T-cytotoxic cells), release of a range of cytokines and ...
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<p>COVID-19 in Children: An Ample Review</p>
... coronavirus 2 [SARS-CoV-2]) in children, from epidemiological, clinical, and laboratory perspectives, including knowledge on the disease course, treatment, and ...on COVID-19 ...
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Coronavirus Disease 2019 Assosiated Pneumonia in China: Current Status and Future Prospects
... the SARS-CoV-2 was reported in Wuhan, Hubei Province, China in December ...of SARS-CoV-2 in China threatened the population greatly due to the high incidence of fatal respiratory ...
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