satellite cell
Epigenetic regulation of satellite cell activation during muscle regeneration
... in satellite-cell-mediated muscle ...symmetrical cell division will express Pax7 and the genes involved in cell-cycle ...asymmetrical cell division, one of the two cells will go on to ...
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BMP signaling regulates satellite cell dependent postnatal muscle growth
... how satellite cell-derived BMPs signal to neighboring cells and whether this defines the respective position of satellite cells within their ...determines satellite cell-dependent ...
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Satellite cell content in Huntington’s disease patients in response to endurance training
... area, satellite cell con- tent, myonuclear number, and myonuclear domain were determined from vastus lateralis muscle biopsies at rest and after 26 weeks of endurance training in HD patients and healthy ...
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Dorsal root ganglia in Friedreich ataxia: satellite cell proliferation and inflammation
... by satellite cells. While monocytes gain access to the satellite cell layer sur- rounding normal human DRG and mingle with satellite cells, S100 and IBA1 reaction products do not co- localize ...
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Hesr1 and Hesr3 are essential to generate undifferentiated quiescent satellite cells and to maintain satellite cell numbers
... adult satellite cells and examined the physiological roles of Hesr1 and Hesr3 in skeletal ...dKO satellite cells (see ...the satellite cell pool and decreases in myofiber number at P7 (data ...
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COUP TFII regulates satellite cell function and muscular dystrophy
... Duchenne muscular dystrophy (DMD) is a severe and progressive muscle-wasting disease caused by mutations in the dystrophin gene. Although dystrophin deficiency in myofiber triggers the disease’s pathological changes, the ...
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Signaling for Muscular Hypertrophy May Exist with or without Activation of Satellite Cell
... through satellite cell activation and Fzd7 receptor binding, which is also involved in activation of the PI3K-Akt- mTOR pathway (Schiaffino et al, ...
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The muscle satellite cell at 50: the formative years
... that satellite cell/ myoblast transplantation may be a therapy for muscle dis- ease [123] and led to a series of human trials (reviewed in ...identifying satellite cells [112,124,125], and for ...
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Muscle PGC-1α modulates satellite cell number and proliferation by remodeling the stem cell niche
... experiment, satellite cell and myoblast numbers were quantified on approximately 60 fibers/mouse for T0 or approximately 20 fibers/ mouse for T3 and expressed per ...
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PPARδ regulates satellite cell proliferation and skeletal muscle regeneration
... and satellite cell ...of satellite cells, which will have become com- mitted to the myogenic ...metric cell division [15]. Myf5-null satellite cells are defective in transient ...
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Satellite cell depletion prevents fiber hypertrophy in skeletal muscle
... McCarthy et al. (2011) did not report CSA averages, but from their CSA histogram we calculated that the average overload hypertrophy was ≈ 11% in SC+ muscles, and similarly so also in a more recent paper (Kirby et al., ...
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Pervasive satellite cell contribution to uninjured adult muscle fibers
... of satellite cells in adult muscle are pre- sumed quiescent [11] and are thought to rarely activate, proliferate, and fuse into existing myofibers ...strate satellite cell intrinsic deficits in ...
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A role for RNA post-transcriptional regulation in satellite cell activation
... resident satellite cells [12,13] lead to the speculation that metabolic activity in these cells is ...quiescent satellite cells with high levels of Pax7 express reduced levels of mitochon- drial genes ...
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Satellite Cell Plasticity in the Chicken Embryo
... the satellite cell. Satellite cells are defined by their morphological criteria as occupying grooves between the basal lamina and sarcolemma of the muscle ...fiber. Satellite cells define a ...
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Extrinsic regulation of satellite cell specification
... as satellite cells. The satellite cell pool is responsible for the remarkable regenerative capacity of skeletal ...development, satellite cells are capable of self-renewal and can give rise to ...
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Effective fiber hypertrophy in satellite cell depleted skeletal muscle
... Surgical removal of synergist muscles (gastrocnemius and soleus) places a mechanical overload on the remaining plantaris muscle resulting in robust hypertrophy as demonstrated by a twofold change in mass within two weeks ...
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The satellite cell as a companion in skeletal muscle plasticity: currency, conveyance, clue, connector and colander
... defined satellite cells per se may be distinct from interstitial and circulating stem-like ...of satellite cells that have more stem-like properties and may commit to alternate lineages ...the ...
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Eph/ephrin interactions modulate muscle satellite cell motility and patterning
... the satellite cell response to physiological levels of native ephrins, we capitalized on two ephrin-mediated cell migration events in the developing quail embryo: emigration of cranial neural crest ...
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Satellite cell therapy – from mice to men
... other cell types, both within and without skeletal muscle, have been shown to display varying degrees of myogenic ...these cell types that have also been extensively studied in humans are mesoangioblasts ...
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Transient HIF2A inhibition promotes satellite cell proliferation and muscle regeneration
... Luciferase assay. A Spry1 promoter region (–341 to +39 bp relative to the transcription start site [TSS]) and a Pdk3 promoter region (–107 to +101 bp relative to the TSS) were PCR amplified from genomic DNA (C57BL/6 ...
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