Scorpion venom
SCORPION VENOM AND ITS COMPONENTS AS NEW PHARMACEUTICAL APPROACH TO CANCER TREATMENT, A SYSTEMATIC REVIEW
... crude scorpion venom in an increasing number of pre-clinical and experimental researches 3 ...choosing scorpion venom and its components as good candidates for cancer ...
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Transcriptome analysis of the Tityus serrulatus scorpion venom gland
... scorpion’s venom is mainly used for prey capture and defence. The venom gland is a complex organ where a large number of substances are ...of venom components, greatly expanding the publicly ...
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The identification and characterisation of antimicrobial peptides from snake and scorpion venom
... snake venom two novel AMPs (6-7KDa) along with four potential phospholipase A2 (PLA2) proteins have been identified (12-14 ...mamba venom (Dendroaspis polylepis) exerts moderate antimicrobial activity and ...
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<p>Pleiotropic Anticancer Properties of Scorpion Venom Peptides: <em>Rhopalurus princeps</em> Venom as an Anticancer Agent</p>
... Since cancer is a complex systemic disease, the need for new therapeutic modalities that can target or block several steps of cancer cell characteristics, modulate or repolarize immune cells, and are less toxic to ...
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Validation of Modified Lowry for the Determination of Total Protein Concentration of Rhopalurus junceus Scorpion Venom
... Rhopalurus junceus scorpion venom is mainly composed by proteins and peptides. The determination of total protein has been determined by Lowry method. However, the reading has been performed in a ...
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The role of dexamethasone in scorpion venom-induced deregulation of sodium and water transport in rat lungs
... Regardless of its pathogenesis, pulmonary edema is resolved by active sodium trans- port across the alveolar epithelium via apical amiloride-sensitive sodium channels and basolateral Na,K-ATPase. This active vectorial ...
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Scorpion venom: pharmacological analysis and its applications
... all scorpion species affect cardiovascular system and cause pulmonary oedema and cardiac arrhythmias ...140]. Scorpion venoms containing bradykinin-potentiating peptides (hypo- tensive agent) have been ...
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Determination of the Median Lethal Dose and Electrophoretic Pattern of Hottentotta saulcyi (Scorpiones, Buthidae) Scorpion Venom
... saulcyi venom to be between 4 and 69 kDa by gradient ...saulcyi scorpion venom possesses both short-chain neurotoxins and long-chain neurotoxins ac- cording to the electrophoretic protein ...
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A3, a Scorpion Venom Derived Peptide Analogue with Potent Antimicrobial and Antibiofilm Activity against Clinical Isolates of Multi-Drug Resistant Gram Positive Bacteria
... In this study, we report the design and functional characterization of the antimicrobial, antibiofilm and mammalian cytotoxic activity of a synthetic scorpion venom peptide analogue named A3. The ...
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Characterization of Functional Effects of Two New Active Fractions Isolated From Scorpion Venom on Neuronal Ca2+ Spikes: A Possible Action on Ca2+-Dependent Dependent K+ Channels
... including scorpion toxins target voltage- gated ion channels, they may have profound effects on excitable ...particularly scorpion toxins would be helpful in future drug development ...
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The Effects of Isolated Fractions of Mesobuthus eupeus Scorpion Venom on Humoral Immune Response
... The venom fractions were purified by ion exchange chromatography. Anion-exchange chromatography was performed using diethyl- aminoethyl cellulose (DEAE-C) column (Sig- ma, Product Number: D3764) at a flow rate of ...
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Phospholipid dependent mechanism of smp24, an α-helical antimicrobial peptide from scorpion venom
... Scorpion venoms are a rich source of antimicrobial peptides [16,17]. In this study we have examined the mechanism of action of Smp24 (24 amino acids, charge + 3), a prototypical amphipathic AMP that was identi fi ...
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The Occurrence of 5 Hydroxytryptamine in Scorpion Venom
... This paper is concerned with the methods of identification and assay of this substance in venom, and also considers the histochemistry of the venom gland in relation to this rinding.. ME[r] ...
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Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice
... scorpion (C. exilicauda). Taken together, our studies of the ability of mast cells to enhance resistance to the venoms of 3 poisonous snakes and 1 venomous lizard, as well as 3 venomous arthropods, suggest that ...
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Cytotoxic effects of Smp24 and Smp43 scorpion venom antimicrobial peptides on tumour and non tumour cell lines
... Scorpion venoms are cocktails of diverse biologically active compounds (see, inter alia, Rodriguez de la Vega and Possani, 2005; Rodriguez de la Vega et al. 2010; Cao et al. 2014; Abdel-Rahman et al. 2015; ...
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Phospholipid dependent mechanism of smp24, an α helical antimicrobial peptide from scorpion venom
... Scorpion venoms are a rich source of antimicrobial peptides [16,17]. In this study we have examined the mechanism of action of Smp24 (24 amino acids, charge + 3), a prototypical amphipathic AMP that was identi fi ...
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Preparation and biodistribution study of a 99mTc-labeled toxic fraction of Iranian mesobuthus eupeus scorpion venom
... In this study preparation, purification, labeling of Iranian Mesobuthus eupeus (IMe) and biological behavior of labeled compound through biodistribution studies in normal mice is eva[r] ...
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Changes in predator exposure, but not diet induce phenotypic plasticity in scorpion venom
... each scorpion (A) and loadings for each venom fraction (B, 14 total peaks) with fraction number indicated at the tips of each ...defensive venom treatment is indicated in dark (+ pressure for ...
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Physiochemical And Biological Study Of And Hemiscorpius Persicus Scorpion Venom (Birula, 1903)
... of scorpion envenomation in Khuzestan, southwest province of Iran (Taghavi et al, ...The venom of this species is used in the production of scorpion polyvalent antiserum (Latifi, ...a scorpion ...
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Cardiotoxic and Arrhythmogenic Effects of Hemiscorpius lepturus Scorpion Venom in Rats
... lepturus venom (25 µg/100 l) treatment caused a negative inotropic ...by venom injection. Pre venom treatment (20 min) of Razi Institute antivenom (10 µl) neutralized cardiotropic effects but post ...
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