Secretory pathway
An Alternative Terminal Step of the General Secretory Pathway in Staphylococcus aureus
... the pathway awaits de- tailed analysis of these proteins as well as the signal responsible for derepression of the operon, which is in ...Sec pathway will lead to a greater understanding of secretion and ...
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Rab6 and the secretory pathway affect oocyte polarity in Drosophila
... By regulating the transport of proteins and lipids toward the plasma membrane, the secretory pathway plays an important function in cell polarity. Rab GTPases are important regulatory factors of vesicular ...
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Subcellular localization and trafficking of phytolongins (non SNARE longins) in the plant secretory pathway
... Our results show that the four phytolongins Phyl1.1, Phyl1.2, Phyl2.1, and Phyl2.2 are targeted to different mem- branes of the secretory pathway. While Phyl2.1 and Phyl2.2 are exclusively present in the ER ...
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Integrity of the Early Secretory Pathway Promotes, but Is Not Required for, Severe Acute Respiratory Syndrome Coronavirus RNA Synthesis and Virus-Induced Remodeling of Endoplasmic Reticulum Membranes
... early secretory pathway interacts with the RVN and the viral replication/transcription complex (RTC) that is anchored to ...the secretory pathway was disrupted by brefeldin A (BFA) treatment ...
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Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway
... autophagy-based secretory pathway, and the secreted IDE could then degrade extracellular ...conventional secretory pathway, as MMP-9 has signal peptides for secretion ...
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BPIFB6 Regulates Secretory Pathway Trafficking and Enterovirus Replication
... regulates secretory pathway trafficking and its RNAi-mediated depletion disrupts both anterograde and retrograde trafficking and induces pronounced Golgi complex ...
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Secretory pathway of cellulase: a mini-review
... IV secretory pathway, the mechanism seems to be more related to clinical settings, where bac- terial conjugation is problematic because it leads to a rapid dissemination of antibiotic resistance genes and ...
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Saccharomyces cerevisiae Grx6 and Grx7 Are Monothiol Glutaredoxins Associated with the Early Secretory Pathway
... Saccharomyces cerevisiae Grx6 and Grx7 are two monothiol glutaredoxins whose active-site sequences (CSYS and CPYS, respectively) are reminiscent of the CPYC active-site sequence of classical dithiol glutaredoxins. Both ...
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Hijacking Components of the Cellular Secretory Pathway for Replication of Poliovirus RNA
... The secretory pathway conducts traffic of cargo that is destined for insertion into the plasma membrane or secretion from the cell; autophagy is the major self-degradative ...
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Coat flexibility in the secretory pathway: a role in transport of bulky cargoes
... In Dropsophila, TANGO1 is proposed to be a general secretion regulator, although it is clear that bulky cargo have a lower tolerance to TANGO1 depletion than ‘standard’ cargo [10 ]. Given that Drosophila lack many of the ...
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The cellular secretory pathway is not utilized for biosynthesis, modification, or intracellular transport of the simian virus 40 large tumor antigen.
... This prediction presented an in vivo approach by which to assess the role of the secretory pathway in T-ag biosynthesis and transport, i.e., free and membrane-bound polyribosomes were pu[r] ...
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Calcium-containing phosphopeptides pave the secretory pathway for efficient protein traffic and secretion in fungi
... vesicle-mediated secretory pathway in filamentous fungi, apparently because they change the calcium concentration in organelles that act as calcium ...of secretory proteins by interacting with the ...
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The Hydrophobic Domain of Infectious Bronchitis Virus E Protein Alters the Host Secretory Pathway and Is Important for Release of Infectious Virus
... the secretory pathway in order to properly traffic its ...the secretory pathway using a different route, or they may require different machinery than conven- tional ...
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Coordinated activation of the secretory pathway during notochord formation in the Xenopus embryo
... We also tested whether overexpression of Xbp1 or Creb3l2 could activate secretory pathway genes in the embryo. We used animal explants (caps) that do not develop into notochord on their own but can be ...
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Effect of secretory pathway gene overexpression on secretion of a fluorescent reporter protein in Aspergillus nidulans
... may not result in high enough throughput to saturate the system. It has previously been shown that increased gene copy number may result in increased secretion [32]. Thus, if the system is not saturated, overexpres- sion ...
14
Secretory Protein Biogenesis and Traffic in the Early Secretory Pathway
... entire pathway was revolutionary in terms of being able to define novel functions based on shared genetic ...early secretory pathway components, quantify- ing the phenotypic cost of combined mutations ...
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Effects of Foot-and-Mouth Disease Virus Nonstructural Proteins on the Structure and Function of the Early Secretory Pathway: 2BC but Not 3A Blocks Endoplasmic Reticulum-to-Golgi Transport
... Effect of FMDV P2 proteins on transport through the se- cretory pathway. The experiments described above suggested that FMDV 3A does not stop movement of membrane pro- teins from the ER to the cell surface. ...
14
Interactions between Melanin Enzymes and Their Atypical Recruitment to the Secretory Pathway by Palmitoylation
... atypical secretory pro- teins and some conventional secretory proteins (see Table S2 in the supplemental material), it is plausible that forming a complex with conventional secretory proteins of the ...
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An investigation into the regulated secretory pathway of granulocytes
... constitutive secretory pathway, the function o f each ARF family member has still to be ...regulated secretory pathway would increase both our understanding o f ARF function and o f the ...
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Novel Mechanisms In The Sorting Of Proglucagon To The Secretory Granules Of The Regulated Secretory Pathway
... the secretory pathway, and that in doing so, provides an thermodynamically efficient mechanism condensation, which then enter granules as electron-dense ...from secretory granules of atrial ...
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