Serotonin receptor
Serotonin receptor modulators in the treatment of irritable bowel syndrome
... of serotonin receptor modulators used in the treatment of irritable bowel ...syndrome. Serotonin is an important monoamine neurotransmitter that plays a key role in the initiation of peristaltic and ...
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Serotonin receptor 1A–modulated phosphorylation of glycine receptor α3 controls breathing in mice
... the serotonin receptor (5-HTR) family, have been considered in the past (23), but their intracellular basis have not been fully estab- ...a receptor-spe- cific pattern along parallel intracellular ...
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Serotonin stimulates [Ca2+]i elevation in ciliary ectodermal cells of echinoplutei through a serotonin receptor cell network in the blastocoel
... the serotonin receptor cell network (SRN) with the ectoderm in ...anti- serotonin antibody-binding sites were visualized with Alexa Fluor 488-conjugated goat anti-rabbit IgG (H+L) or Alexa Fluor ...
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Serotonin Receptor Agonist 5-Nonyloxytryptamine Alters the Kinetics of Reovirus Cell Entry
... Nogo-1 receptor (depending on the cell type) and enters cells by receptor-mediated ...prototype serotonin receptor agonist, diminished reovirus ...a serotonin antagonist, enhanced ...
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Association of serotonin receptor 2a haplotypes with obsessive–compulsive disorder and its treatment response in Iranian patients: a genetic and pharmacogenetic study
... behaviors. Serotonin reuptake inhibitors are used for OCD treatment, but 40%–60% of patients do not respond to them ...of serotonin receptor 2a polymorphisms rs6311 and rs6313 with OCD, its familial ...
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Lorcaserin and pimavanserin: emerging selectivity of serotonin receptor subtype–targeted drugs
... of serotonin are mediated by fourteen ...5-HT receptor subtypes has been only occasionally ...5-HT receptor pharmacology and discusses two recent 5-HT receptor subtype–selective drugs, ...
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Serotonin receptor agonists in the acute treatment of migraine: a review on their therapeutic potential
... F receptor, structurally different from the triptans, with a greater 5-HT1 F receptor selectivity than LY334370 and with minimized inter- actions with 5-HT1 A , 5-HT1 B , and 5-HT1 D receptors to avoid ...
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Neurovascular and neuroimaging effects of the hallucinogenic serotonin receptor agonist psilocin in the rat brain.
... The pharmacological MRI phMRI response to psilocin is characterised in rats Region specific increases and decreases in phMRI signals are observed Underlying neuronal and haemodynamic cha[r] ...
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Role of the Serotonin Receptor 7 in Brain Plasticity: From Development to Disease
... the receptor in these neuropsychiatric ...this receptor in anxiety/depression and schizophrenia, and its potential involvement for the treatment of these neuropsychiatric ...
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The atypical antipsychotic olanzapine causes weight gain by targeting serotonin receptor 2C
... underlying these drug-induced metabolic perturbations remain poorly understood. Here, we used an experimental model that reproduces olanzapine-induced hyperphagia and obesity in female C57BL/6 mice. We found that ...
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Clinical significance of pharmacogenomic studies in tardive dyskinesia associated with patients with psychiatric disorders
... Abstract: Pharmacogenomics is the study of the effects of genetic polymorphisms on medication pharmacokinetics and pharmacodynamics. It offers advantages in predicting drug efficacy and/or toxicity and has already ...
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Hyperprolactinemia in Thai children and adolescents with autism spectrum disorder treated with risperidone
... In all cases, baseline prolactin levels prior to the initiation of antipsychotic therapy were not available for comparison, and no comparable group on another atypical antipsychotic agent was available. All participants ...
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Studies of the Serotonin Type 3A Receptor and the Chemical Preparation of tRNA
... As new people joined the Dougherty group, I made new friends and colleagues who each contributed in their own way. Much of my time overlapped with Ethan Van Arnem, Kristina Daeffler, and Ximena da Silva. I thank Ximena ...
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Interventions to decrease the risk of adverse cardiac events for post-surgery or chemotherapy patients taking serotonin (5-HT3) receptor antagonists: protocol for a systematic review and network meta-analysis
... as serotonin receptor antagonists, is often prescribed for patients experiencing these ...that serotonin receptor antagonists can cause harm, including ...with serotonin receptor ...
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Evidence for Possible Involvement of 5-HT2B Receptors.pdf
... Background—Serotonergic medications with various mechanisms of action are used to treat psychiatric disorders and are being investigated as treatments for drug dependence. The occurrence of fenfluramine-associated ...
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Administration of Ondansetron Is Associated With Lethal Outcome
... Ondansetron is an antiemetic agent that derives its therapeutic effect from serotonin receptor antagonism. On- dansetron currently accounts for ⬃ 3% of antiemetic prescriptions to children with ...
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Key words
... Recent literature confirms the importance of genetic factors for undertaking exercise, especially in males [1, 2]. One of the elements that influ- ences physical activity is the serotoninergic system [3]. The dysfunction ...
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THE 1-(2,3-DICHLOROPHENYL)-PIPERAZINE-TO-ARIPIPRAZOLE RATIO AT STEADY STATE IN RATS AND SCHIZOPHRENIC PATIENTS
... causing serotonin receptor-related effects, the authors examined the compounds’ concentrations in brain of rats given 10 mg/kg aripiprazole dihydrochloride orally, approximately every half-life for five ...
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Social status differences regulate the serotonergic system of a cichlid fish, Astatotilapia burtoni
... although serotonin cells are not neuropeptide- producing cells per se, we hypothesized social status correlates with cell size differences because, in adult rats, changes in stress hormone levels can produce 5-HT ...
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Functional expression of serotonin 5 HT7 receptor in human glioblastoma cell lines
... glioblastoma cells, the presence of this protein was then investigated by Western blotting, using a specific antibody raised against a sequence identical for all human receptor splice variants. Two bands, with ...
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