Serum amyloid
Serum amyloid A – a review
... example, amyloid deposits in multiple myeloma comprise fibrillar arrays of fragments of immunoglobulin light ...in amyloid deposits is ...aa) serum protein that was initially presumed and later shown ...
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Expression of serum amyloid A in uterine cervical cancer
... Serum amyloid A (SAA) is a positive acute-phase protein with four different isotypes in humans. SAA is generated primarily by the liver in response to trauma, infection, inflammation, and even neoplastic ...
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Plasma clearance kinetics of the amyloid related high density lipoprotein apoprotein, serum amyloid protein (apoSAA), in the mouse Evidence for rapid apoSAA clearance
... The plasma clearance kinetics of the amyloid-related high density lipoprotein HDL apoprotein serum amyloid protein apoSAA was examined in BALB/c mice by two different methods, using labe[r] ...
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Serum Amyloid P Component Binds Fungal Surface Amyloid and Decreases Human Macrophage Phagocytosis and Secretion of Inflammatory Cytokines
... protein serum amyloid P component (SAP) (also called PTX2) to Candida al- bicans dampens the innate immune response to this ...surface amyloid-like structures important for adhesion and biofilm forma- ...
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Influenza Virus Infection is not Affected by Serum Amyloid P Component
... Serum amyloid P component (SAP), a normal plasma protein of the pentraxin family (1), binds specifically to amyloid fibrils, to certain anionic gly- cans, to DNA, chromatin and apoptotic cells, and ...
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Agreement between commercial assays for haptoglobin and serum amyloid A in goats
... and serum amyloid A (SAA) are considered as the major acute phase proteins (APPs) in ...138 serum samples, respectively, as 5 and 14 paired measure‑ ments, respectively, were excluded from agreement ...
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Factors Influencing Serum Amyloid Type A (Saa) Concentrations in Horses
... The acute phase response (APR) is the reaction that occurs in animals in response to disturbances in hemostasis follow- ing tissue damage. In horses, the APR is manifested in a variety of pathological processes of ...
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Kinetics of serum amyloid protein A in casein induced murine amyloidosis
... Serum amyloid protein A (SAA), the precursor of secondary amyloid protein, is elevated in chronic diseases which are associated with an increased incidence of ...
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The prognostic value of serum amyloid A in solid tumors: a meta-analysis
... [5]. Serum amyloid A (SAA) is an acute-phase, hepatic protein secreted in the course of acute infections and tissue damage, the expression of which is induced by several cytokines, including IL-1, IL-6, and ...
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Serum Amyloid A: EVIDENCE FOR ITS ORIGIN IN POLYMORPHONUCLEAR LEUKOCYTES
... the amyloid A content of the culture medium and of sonicated, 2 × 10 6 cells was determined by ...of amyloid A-related material in the sonicated granulocytes compared with the individuals' serum ...
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Tissue specific expression of serum amyloid A
... The human serum amyloid A family o f proteins is comprised o f two acute phase proteins (SAAl and SAA2) and one constitutively expressed protein (SAA4).. The SAAs are predomina[r] ...
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In vitro interaction of soluble and amyloid form of serum amyloid a protein to bc3h1cells
... localized amyloid seems to be the maximum ...systemic amyloid condition the serum amyloid protofibrils pass the blood brain-barrier and bind widely in the parenchymal region (Asokan, ...the ...
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Original Article Serum amyloid A expression is associated with breast cancer survival
... MCF-7 cell lines by immunofluorescence. Additionally, we showed that the elevated SAA induced the proliferation, migration, and inva- siveness of MCF-7 cells in a dose-dependent manner. These findings are similar to ...
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In-vitro interaction of b-crystallin on serum amyloid a and serum amyloid a fibrils with bc3h1 cells
... of Serum Amyloid A (SAA) and Serum Amyloid A protofibrils with BC3H1 cells of the mouse are dealt with in detail to study the binding of SAA protofibrils in various ...
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The prognostic value of serum C-reactive protein-bound serum amyloid A in early-stage lung cancer
... The affinity-purified proteins were applied to 8%–14% gradient gels for SDS-PAGE. After staining with 0.5% Coomassie brilliant blue G-250, the lane with a molecular weight of approximately 12 kDa, which was only present ...
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Investigation of the solubility and the potentials for purification of serum amyloid A (SAA) from equine acute phase serum – a pilot study
... dried serum dissolved in Milli-Q water, however, suggests more hydrophilic properties than previously be- lieved, or suggests interactions between SAA and other serum substances with more hydrophilic ...
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Suppression of LPS-induced tau hyperphosphorylation by serum amyloid A
... bovine serum (FBS) and 3 μg/ml cytosine-β-D-arabinofuranoside (Ara-C, Sigma) in the following 3 days and then again switched back to neurobasal medium containing 2 % B-27® ...
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Human Serum Amyloid P Component is a Single Uncomplexed Pentamer in Whole Serum
... whole serum samples, eluted from gel filtra- tion columns clearly ahead of ...man serum, SAP sedimented as single pentamers not complexed with any macromolecular ligand, regard- less of the presence or ...
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Occupational exposure levels of bioaerosol components are associated with serum levels of the acute phase protein Serum Amyloid A in greenhouse workers
... without atopy and asthma was 11.1 mg/l (median = 26.5 mg/l), which is also higher than median levels in healthy Swedish individuals. This may be due to endotoxin exposure; on the other hand the reference group also had ...
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Serum amyloid A impairs the antiinflammatory properties of HDL
... The purpose of the present study was to determine whether HDL from inflamed mice and humans loses its ability to inhibit palmitate-induced inflammation and to facilitate cholesterol effl[r] ...
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