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Serum Amyloid A (SAA)

Serum amyloid A – a review

Serum amyloid A – a review

... example, amyloid deposits in multiple myeloma comprise fibrillar arrays of fragments of immunoglobulin light ...in amyloid deposits is ...aa) serum protein that was initially presumed and later shown ...

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Expression of serum amyloid A in uterine cervical cancer

Expression of serum amyloid A in uterine cervical cancer

... Serum amyloid A (SAA) is a positive acute-phase protein with four different isotypes in humans. SAA is generated primarily by the liver in response to trauma, infection, inflammation, and even neoplastic ...

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Human Serum Amyloid A Protein Inhibits Hepatitis C Virus Entry into Cells

Human Serum Amyloid A Protein Inhibits Hepatitis C Virus Entry into Cells

... Serum amyloid A (SAA) is an acute-phase protein induced by a variety of inflammatory stimuli, including bacterial and viral infections. SAA was recently found to function as an opsonin for gram-negative ...

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Acute phase serum amyloid A production by rheumatoid arthritis synovial tissue

Acute phase serum amyloid A production by rheumatoid arthritis synovial tissue

... Introduction: Serum amyloid A (SAA) is the circulating precursor of amyloid A protein, the fibrillar component of amyloid deposits. In humans, four SAA genes have been described. Two genes ...

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Serum amyloid A expression in the breast cancer tissue is associated with poor prognosis

Serum amyloid A expression in the breast cancer tissue is associated with poor prognosis

... Serum amyloid A (SAA), a positive acute-phase protein, is generated primarily by the liver in response to trauma, infection, inflammation, and even neoplastic ...

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Original Article Serum amyloid A expression is associated with breast cancer survival

Original Article Serum amyloid A expression is associated with breast cancer survival

... Abstract: Serum amyloid A (SAA) is an acute-phase inflammatory protein. A growing body of evidence supports the role of SAA in carcinogenesis and metastasis. Thus, SAA has been suggested as a biomarker for ...

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The prognostic value of serum amyloid A in solid tumors: a meta-analysis

The prognostic value of serum amyloid A in solid tumors: a meta-analysis

... [5]. Serum amyloid A (SAA) is an acute-phase, hepatic protein secreted in the course of acute infections and tissue damage, the expression of which is induced by several cytokines, including IL-1, IL-6, and ...

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Agreement between commercial assays for haptoglobin and serum amyloid A in goats

Agreement between commercial assays for haptoglobin and serum amyloid A in goats

... and serum amyloid A (SAA) are considered as the major acute phase proteins (APPs) in ...138 serum samples, respectively, as 5 and 14 paired measure‑ ments, respectively, were excluded from agreement ...

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Human serum amyloid A  Three hepatic mRNAs and the corresponding proteins in one person

Human serum amyloid A Three hepatic mRNAs and the corresponding proteins in one person

... Serum amyloid A protein (SAA) is a major acute-phase protein in humans and most other ...the serum precursor of the major protein constituent of reactive amyloid ...and amyloid A ...

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In vitro interaction of soluble and amyloid form of serum amyloid a protein to bc3h1cells

In vitro interaction of soluble and amyloid form of serum amyloid a protein to bc3h1cells

... of Serum Amyloid A (SAA) and Serum Amyloid A protofibrils with BC3H1 cells of the mouse are dealt with in detail to study the binding of SAA protofibrils in various ...of Serum ...

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In-vitro interaction of b-crystallin on serum amyloid a and serum amyloid a fibrils with bc3h1 cells

In-vitro interaction of b-crystallin on serum amyloid a and serum amyloid a fibrils with bc3h1 cells

... of Serum Amyloid A (SAA) and Serum Amyloid A protofibrils with BC3H1 cells of the mouse are dealt with in detail to study the binding of SAA protofibrils in various ...

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Serum Amyloid A: EVIDENCE FOR ITS ORIGIN IN POLYMORPHONUCLEAR LEUKOCYTES

Serum Amyloid A: EVIDENCE FOR ITS ORIGIN IN POLYMORPHONUCLEAR LEUKOCYTES

... the amyloid A content of the culture medium and of sonicated, 2 × 10 6 cells was determined by ...of amyloid A-related material in the sonicated granulocytes compared with the individuals' serum ...

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Tissue specific expression of serum amyloid A

Tissue specific expression of serum amyloid A

... The human serum amyloid A family o f proteins is comprised o f two acute phase proteins (SAAl and SAA2) and one constitutively expressed protein (SAA4).. The SAAs are predomina[r] ...

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Serum amyloid A primes microglia for ATP-dependent interleukin-1β release

Serum amyloid A primes microglia for ATP-dependent interleukin-1β release

... vitality/function [39, 40]. Cells were primed by pre-treating with 0.1 μg/ml LPS (optimal concentration chosen from preliminary experiments) [18, 37, 41] or different concentrations of recombinant human Apo-SAA (as ...

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Serum Amyloid A Was Correlated with Osteonecrosis of the Femoral Head by Affecting Bone Metabolism

Serum Amyloid A Was Correlated with Osteonecrosis of the Femoral Head by Affecting Bone Metabolism

... SAA serum level of steroid-induced, alcohol-induced, trauma-induced ONFH patients and healthy 76.. volunteers.[r] ...

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Investigation of the solubility and the potentials for purification of serum amyloid A (SAA) from equine acute phase serum – a pilot study

Investigation of the solubility and the potentials for purification of serum amyloid A (SAA) from equine acute phase serum – a pilot study

... dried serum dissolved in Milli-Q water, however, suggests more hydrophilic properties than previously be- lieved, or suggests interactions between SAA and other serum substances with more hydrophilic ...

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The prognostic value of serum C-reactive protein-bound serum amyloid A in early-stage lung cancer

The prognostic value of serum C-reactive protein-bound serum amyloid A in early-stage lung cancer

... Results: CRP‑SAA was identified specifically in serum samples from lung cancer patients by proteomic analysis. CRP binding to SAA was confirmed by co‑IP in serum samples from lung cancer patients and cell ...

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Suppression of LPS-induced tau hyperphosphorylation by serum amyloid A

Suppression of LPS-induced tau hyperphosphorylation by serum amyloid A

... response [13]. However, extrahepatic production of SAA has been implicated as being more relevant to the patho- genesis of chronic inflammatory diseases including AD [13]. In mice, SAA is encoded by a family of three ...

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Validity of serum amyloid A and HMGB1 as biomarkers for early diagnosis of gastric cancer

<p>Validity of serum amyloid A and HMGB1 as biomarkers for early diagnosis of gastric cancer</p>

... of serum CEA at cutoff of ...higher serum levels of both SAA and HMGB1 re fl ected higher tumor grade ...Conclusion: Serum levels of both SAA and HMGB1 could be of great value for early diagnosis of ...

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Analysis of the acute phase responses of Serum Amyloid A, Haptoglobin and Type 1 Interferon in cattle experimentally infected with foot-and-mouth disease virus serotype O

Analysis of the acute phase responses of Serum Amyloid A, Haptoglobin and Type 1 Interferon in cattle experimentally infected with foot-and-mouth disease virus serotype O

... The aim of this study was to investigate the innate immune response to infection with FMDV in cattle by measuring systemic levels of acute phase proteins SAA and HP as well as the biological activity of type 1 IFN in ...

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