Sesquiterpene lactones
Acetyl and butyryl cholinesterase inhibitory sesquiterpene lactones from Amberboa ramosa
... As the anti cholinesterase activity of chloroform soluble fraction from Amberboa ramosa has previously been reported [3], keeping in view this point we evaluated the guaianolides (sesquiterpenes) isolated from chloroform ...
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A QSAR study of sesquiterpene lactones from Inula falconeri as potent anti inflammatory agents
... Sesquiterpene lactones from Inula falconeri possess diverse biological activities i.e., anticancer, antibacterial, hepaprotective, cytotoxic, and anti-inflammatory activity. In this work we calculated ...
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Germacranolide type sesquiterpene lactones from Smallanthus sonchifolius with promising activity against Leishmania mexicana and Trypanosoma cruzi
... Literature data indicate that the leaves of this plant have antibacterial, anti-inflammatory and antifungal properties [24 – 26]. We have previously reported the cytotoxicity of six sesquiterpene lactones ...
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Artemisia annua L : evidence of sesquiterpene lactones’ fraction antinociceptive activity
... in sesquiterpene lactones has been significant in eliciting potent inhibitory activity against iNOS-dependent ...of sesquiterpene lactones include activation of p53 and an increase in ROS as ...
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ENHANCEMENT OF ARNICA MONTANA IN VITRO SHOOT MULTIPLICATION AND SESQUITERPENE LACTONES PRODUCTION USING TEMPORARY IMMERSION SYSTEM
... The multiplication rate was significantly increased; moreover, this system ensured obtaining of healthy plants of high quality. TIS integrates advantages of both solid and liquid media, namely maximum gas exchanges and ...
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Sesquiterpene lactones of Iranian Compositae Family (Astraceae); their Chemical Constituents and Anti-Plasmodial Properties of Tehranolide (A.Review)
... Sesquiterpene lactones constitute a large and diverse group of biologically active plant chemical that have been identified in the several plant ...the sesquiterpene lactones are their ...
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Actions of sesquiterpene lactones isolated from Moquiniastrum polymorphum subsp. floccosum in MCF7 cell line and their potentiating action on doxorubicin
... of sesquiterpene lactones, studies have demonstrate, in general, that they act in the signaling pathway of NF-kB, a transcription factor that regulates the expression of more than 150 genes related to the ...
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Antimicrobial activity of sesquiterpene lactones isolated from traditional medicinal plant, Costus speciosus (Koen ex Retz ) Sm
... Sesquiterpene lactones are the most distinctive second- ary metabolites of the members of the Compositae (Asteraceae). However, they have been reported from several plant families, such as Acanthaceae, ...
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Sesquiterpene lactones isolated from indigenous Middle Eastern plants inhibit tumor promoter induced transformation of JB6 cells
... Sesquiterpene lactones isolation and cell treatments Extraction, purification, and identification of the SL β- tan and Sal A from Achillea falcata and Centaurea aine- tensis, respectively, were performed as ...
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Molecular Targets of Dietary Polyphenols with Anti inflammatory Properties
... Several sesquiterpene lactones demonstrated anti-inflammatory properties by inhibiting the binding of the transcription factor NF-κB, as assessed by a gel shift assay.70 Quercetin was re[r] ...
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Phytopharmacological review of Xanthium strumarium L. (Cocklebur)
... Xanthium strumarium L. (Family: Compositae) a medicinal plant commonly found as a weed, is widely distributed in North America, Brazil, China, Malaysia and hotter parts of India. The herb is traditionally used mostly in ...
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A REVIEW ON THE THERAPEUTIC POTENTIALS OF PARTHENOLIDE: A SESQUITERPENE LACTONE
... Although current research focuses on the isolation of major compounds from plant sources, it is still not clear which mechanism of action of the various sesquiterpene lactones is important in the treatment ...
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Dihydroparthenolide diol, a novel sesquiterpene lactone
... The absolute con®guration was determined by re®nement of the Flack parameter. The reported con®guration, which agrees with that of sesquiterpene lactones from higher plants (Fischer et al., 1979), yielded x ...
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PHYTOCHEMICAL AND PHARMACOLOGICAL REVIEW OF PROMISING ANTICANCER ROOT OF SAUSSUREA LAPPA CLARKE (FAMILY: ASTERACEAE)
... the sesquiterpene lactones, dehydrocostus lactone and costunolide, from Saussurea lappa, inspection was done on the cytotoxic and movement/intrusion inhibitory impacts of these mixes against neuroblastoma ...
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PHYTOCHEMICAL AND PHARMACOLOGICAL PROPERTIES OF Vernonia amygdalina: A REVIEW (PAGE 80-96)
... of sesquiterpene lactones (Erasto et ...literature. Sesquiterpene lactones (vernodalinol, vernolepin, vernomygdin, hydroxyvernolide, vernolide and vernodalol) had been reported to inhibit ...
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Identification and quantification of selected metabolites in differently pigmented leaves of lettuce (Lactuca sativa L.) cultivars harvested at mature and bolting stages
... Lettuce, one of the most popular vegetables in terms of production and economic value, ranks second to potato in per capita consumption [1]. It is planted annually in backyards, containers, shade net, and greenhouses ...
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López Antón, Nancy (2006): Identification of novel mechanisms of action contributing to the biological activity of cytotoxic natural compounds. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... This work sought to characterise the mode of cell death induced by distinct sesquiterpene lactones (SQTL) and investigate its consequence on macrophage function as a putative anti-infl[r] ...
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Aromaticine, a sesquiterpene lactone from Amblyopappus pusillus
... Sesquiterpene lactones are known to have biological activity, and some guaianolides have antitumor and citotoxic activities (Rodríguez et al. , 1976). The title compound was isolated from aerial parts of ...
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New Sesquiterpene Hydroquinones from Marine Brown Alga
... the 13 C NMR was characteristic of an exocyclic double bond. These data suggested that compound 1 was a sesquiterpene hydroquinone. On the basis of spectral data structure proposed for this compound, which was ...
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Hydrogen peroxide from cellular metabolism of cystine A requirement for lysis of murine tumor cells by vernolepin, a glutathione depleting antineoplastic
... The evidence presented below implicates cystine metabolism as a previously unappreciated source of intracellular oxidant The sesquiterpene lactone antineoplastic vernolepin acutely stres[r] ...
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