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severe closed head-injury

THE CRITICALLY ILL CHILD: DIAGNOSIS AND MANAGEMENT OF HEAD INJURY

THE CRITICALLY ILL CHILD: DIAGNOSIS AND MANAGEMENT OF HEAD INJURY

... The long term effects of severe closed head injury and pro- tracted coma have been summarized by Richardson.” He evaluated 10 children, co- matose for 7 to 47 days following severe head [r] ...

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Tumor necrosis factor-mediated inhibition of interleukin-18 in the brain: a clinical and experimental study in head-injured patients and in a murine model of closed head injury.

Tumor necrosis factor-mediated inhibition of interleukin-18 in the brain: a clinical and experimental study in head-injured patients and in a murine model of closed head injury.

... Closed head injury (CHI) is the leading cause of mortality and persisting neurological impairment in young people in industrialized countries ...brain injury are mediated in large part by a ...

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Tau phosphorylation induced by severe closed head traumatic brain injury is linked to the cellular prion protein

Tau phosphorylation induced by severe closed head traumatic brain injury is linked to the cellular prion protein

... brain injury (TBI)- linked chronic traumatic encephalopathy are tauopathies, we examined whether similar mechanistic pathways are responsible for both AD and TBI ...following severe TBI in the form of ...

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Experience with prolonged induced hypothermia in severe head injury

Experience with prolonged induced hypothermia in severe head injury

... suffer severe closed TBI, defined as a Glascow Coma Scale (GCS) score below 9 at any time after 6 h following ...with severe TBI were treated with the follow- ing: controlled mechanical ventilation; ...

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Combined [18F]DPA-714 micro-positron emission tomography and autoradiography imaging of microglia activation after closed head injury in mice

Combined [18F]DPA-714 micro-positron emission tomography and autoradiography imaging of microglia activation after closed head injury in mice

... keep the mice in the right position and to allow a slight movement at the moment of the trauma induction. After identification of the impact area over the right fronto- parietal cortex, TBI was induced by a falling ...

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Neuropragmatics: Extralinguistic communication after closed head injury

Neuropragmatics: Extralinguistic communication after closed head injury

... The impairment of communication that is observed in this disease is particularly interesting in that it is often neither linguistic in nature nor related to a linguistic deficit. Many patients, while scoring more or less ...

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Comparative Clinical-Radiologic-Post mortem Study of Diffuse Axonal Injury in Severe Head Injury Patients

Comparative Clinical-Radiologic-Post mortem Study of Diffuse Axonal Injury in Severe Head Injury Patients

... This study was taken up to analyse the Glasgow Coma Scale, Clinical Signs, Radiological Findings, Gross and Microscopic postmortem findings in death as the result of diffuse closed head trauma sustained ...

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Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury

Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury

... LRR was calculated as the time interval from isoflurane discontinuation to the first sign of righting after each impact. Neurological impairment was assessed using the NSS [29] determined at 1h and at 1, 2, and 7d ...

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The Management of Minor Closed Head Injury in Children

The Management of Minor Closed Head Injury in Children

... stead should cover patients from a wide range of settings, including those managed in clinics and of- fices, and if possible, those managed over the phone. These studies should also address the independent prognostic ...

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Early tracheostomy in closed head injuries: experience at a tertiary center in a developing country – a prospective study

Early tracheostomy in closed head injuries: experience at a tertiary center in a developing country – a prospective study

... with severe head trauma is cerebral ...isolated closed head ...isolated closed head injury, that were not considered for surgery by the neuro-surgeon or shifted to ICU, ...

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HIGH BLOOD LEVELS PROCALCITONIN AS SYSTEMIC IMFLAMATORY RESPONSE SYNDROME PREDICTOR IN SEVERE AND MODERATE HEAD INJURY

HIGH BLOOD LEVELS PROCALCITONIN AS SYSTEMIC IMFLAMATORY RESPONSE SYNDROME PREDICTOR IN SEVERE AND MODERATE HEAD INJURY

... Moderate Head Injuryand 22 samples of Severe Head Injury, 34 (85 %) samples was found with high levels of PCT had SIRS with a PCT level cut off point of ...

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Incidence and outcome of cardiac injury in patients with severe head trauma

Incidence and outcome of cardiac injury in patients with severe head trauma

... of severe TBI. The awareness of the possible pres- ence of cardiac injury in these patients and its impact on patient outcome might raise the attention toward cardiac protection in cases with higher ...

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Relationship of Serum S100B Levels and Intracranial Injury in Children With Closed Head Trauma

Relationship of Serum S100B Levels and Intracranial Injury in Children With Closed Head Trauma

... accidental closed head trauma and who underwent cranial computed tomography were enrolled ...intracranial injury (ICI) and long-bone fractures were evaluated through analysis of ...

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Injuries Resulting When Small Children Fall Out of Bed

Injuries Resulting When Small Children Fall Out of Bed

... must conclude that severe head injury and CNS damage or injury of any type are extremely rare when children, aged 5 years or less, fall out of. bed[r] ...

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Guidelines for the Management of Severe Head Injury: Are Emergency Physicians Following Them?

Guidelines for the Management of Severe Head Injury: Are Emergency Physicians Following Them?

... received an individual copy of the completed guidelines. As mentioned previously, no directed dissemination of the guidelines to EPs was ever un- dertaken. Our survey revealed similar management practice patterns within ...

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Severe traumatic brain injury

Severe traumatic brain injury

... brain injury. A critical aspect of preventing secondary brain injury after TBI is the avoidance of secondary brain insults, which would otherwise be well-tolerated but can exacerbate neuronal injury ...

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Outcome in elderly individuals with moderate and severe head injury: a tertiary centre experience

Outcome in elderly individuals with moderate and severe head injury: a tertiary centre experience

... In developing countries like India with increase in industrialization and urbanization the incidence of head injuries is on the rise. The socio-economic burden due to the loss of resources and increase in ...

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HIGH ARTERIAL BLOOD LACTATE AS SIRS PREDICTOR IN PATIENTS WITH SEVERE HEAD INJURY

HIGH ARTERIAL BLOOD LACTATE AS SIRS PREDICTOR IN PATIENTS WITH SEVERE HEAD INJURY

... after head injury. Some studies had shown that head injury affected mitochondrial function through free radical enhancement, calcium influx, mitochondrial permeability transposition pores ...

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The "Skull Flap" a new conceived device for decompressive craniectomy/cranioplasty: Feasibility study on cadaver specimen.

The "Skull Flap" a new conceived device for decompressive craniectomy/cranioplasty: Feasibility study on cadaver specimen.

... thanking to the large surface. Load‑bearing testing of the craniectomies were completed using the universal test machine Zwick 1485 (Zwick, Inc., Ulm, Germany), applying a defined quasi‑static (V = 5 mm/min) mechanical ...

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Closed Head Injury And Its Ocular Manifestations: A Clinical StudyRamabhilash Dubey, Aditi Dubey, Yogeshwar Prasad Shukla, Salil Kumar

Closed Head Injury And Its Ocular Manifestations: A Clinical StudyRamabhilash Dubey, Aditi Dubey, Yogeshwar Prasad Shukla, Salil Kumar

... head injury cases due to high impact velocity, as the lateral part of face is more exposed floor and lateral wall fractures are more commonly ...of head injury by the ophthalmologist. As the ...

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