Severe hypertriglyceridemia
Compound but non-linked heterozygous p.W14X and p.L279 V LPL gene mutations in a Chinese patient with long-term severe hypertriglyceridemia and recurrent acute pancreatitis
... The proband had long-term hypertriglyceridemia and had several fasting serum TG measurements on record since 1982. After first checking his recovery in our center in May 2017, we measured his fasting blood glucose ...
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Management of severe hypertriglyceridemia due to lipoprotein lipase deficiency in children
... ketoacidosis, hypertriglyceridemia and acute pancreatitis, in which rapid lowering of TG was observed ...monogenic hypertriglyceridemia, rapid accumulation of TG can occur after plasmapheresis if dietary ...
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Severe hypertriglyceridemia in a subject with disturbed life style and poor glycemic control without recurrence of acute pancreatitis: a case report
... severe hypertriglyceridemia. And total care for T2DM and hypertriglyceridemia is very important for the improve- ment of very severe ...very severe hypertriglyc- eridemia alone does not ...
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A novel APOC2 gene mutation identified in a Chinese patient with severe hypertriglyceridemia and recurrent pancreatitis
... Paradoxically, both excess and deficiency of ApoCII are associated with hypertriglyceridemia. Transgenic mice overexpressing human ApoCII had marked hypertriglyc- eridemia and the ApoCII levels positively ...
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Frequency of rare mutations and common genetic variations in severe hypertriglyceridemia in the general population of Spain
... Another objective our study was to determine the fre- quency of pathogenic mutations causing high TG levels in LPL, LMF1, APOA5, GPIHBP1, APOC2 and APOE genes in subjects with primary HTG. The analysis of the ...
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A novel lipoprotein lipase gene missense mutation in Chinese patients with severe hypertriglyceridemia and pancreatitis
... to severe HTG while one defective LPL allele may have normal to moderately increased blood levels of fasting triglyceride ...a severe HTG and acute ...
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Identification of a novel and heterozygous LMF1 nonsense mutation in an acute pancreatitis patient with severe hypertriglyceridemia, severe obesity and heavy smoking
... The patient was a 32-year-old man with severe obesity (Body Mass Index (BMI) = 35) and heavy smoking (ten cigarettes per day for more than ten years). He was diagnosed to have moderate HTG (fasting serum TG ...
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Update on the management of severe hypertriglyceridemia – focus on free fatty acid forms of omega-3
... Abstract: High levels of plasma triglycerides (TG) are a risk factor for cardiovascular diseases, often associated with anomalies in other lipids or lipoproteins. Hypertriglyceridemia (HTG), particularly at very ...
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Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes
... chylomicrons. This is especially significant in the lung where marginated chylomicrons prevent red cell contact with the endothelium, a phenomenon which is presumably the cause of cyanosis and death in these mice. ...
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Incidence of pancreatitis, secondary causes, and treatment of patients referred to a specialty lipid clinic with severe hypertriglyceridemia: a retrospective cohort study
... At initial visit, almost as many patients were being trea- ted by their referring physician with statin monotherapy as fibrate monotherapy, the recommended first line treatment for severe HTG. Lipid specialists, ...
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Icosapent ethyl for the treatment of severe hypertriglyceridemia
... Abstract: Hypertriglyceridemia is a highly prevalent lipid abnormality and it is associated with atherosclerosis, with a growing body of evidence linking elevated triglycerides (TGs) with cardiovascular ...
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Severe hypertriglyceridemia in Norway: prevalence, clinical and genetic characteristics
... All individuals >18 years treated for sHTG at the Lipid Clinic from January 1st 2002 to December 31st 2007 were identified by searching the medical records for the diagnoses (ICD-10 classification): pure hypertriglyc- ...
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Use of Plasmapheresis in Acute Pancreatitis Secondary to Hypertriglyceridemia
... of hypertriglyceridemia in patients with sudden onset severe hypertriglyceridemia and acute pancreatitis; however, only limited reports of plasmapheresis as a treatment modality have been ...
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Lowering triglycerides to modify cardiovascular risk: will icosapent deliver?
... at severe levels is an important risk factor for pancreatitis, and persistently high triglyceride levels despite optimal LDL-C control conveys increased residual risk of cardiovascular ...in ...
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Plasmapheresis to Treat Hypertriglyceridemia in a Child With Diabetic Ketoacidosis and Pancreatitis
... and severe persistent hypertriglyceridemia. The severe hypertriglyceridemia was treated with 1 course of plasmapheresis, which corrected the triglyceride level and was temporally associated ...
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Moderate Hypertriglyceridemia Revealed by Acute Chest Syndrome, a Milky Appearance Serum and Prior History of Recurrent Acute Pancreatitis in a Type 2 Diabetes Black Patient: A Case Report
... that hypertriglyceridemia is less frequent in Blacks and the risk of pancreatitis increases with severe hypertriglyceridemia, we herein report on a case of moderate hypertriglyceridemia ...
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A novel homozygous mutation in the glycerol-3-phosphate dehydrogenase 1 gene in a Chinese patient with transient infantile hypertriglyceridemia: a case report
... primary hypertriglyceridemia with onset in in- fancy ...of hypertriglyceridemia in GPD1 deficiency is un- clear and remains to be further ...of hypertriglyceridemia on patients with HTGTI is unknown, ...
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Original Article Complement activation in the arteries of patients with severe atherosclerosis
... with severe AS who were enrolled in Zhongshan Hospital for curative sur- gery between 2011 and 2013 and stained the deposition of C3b/iC3b and MAC, two impor- tant complement activation products by ...79 ...
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CLEARANCE OF POSTPRANDIAL LIPIDS IS DELAYED IN SUBJECTS WITH CARDIOVASCULAR DISEASE
... postprandial hypertriglyceridemia and significant delay in postprandial- triglyceride clearance following a standardized fat load in patients with cardiovascular ...
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Metabolic Syndrome and Perioperative Complications during Scheduled Surgeries with Spinal Anesthesia
... studied during perioperative period along with some strategies to reduce such risks [32] [33], leading to the knowledge of MS implications in scenarios such as an intensive care unit and general anesthesia [34], ...
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