Severe neutropenia
Main Determinants of Severe Neutropenia in Patients with Solid Tumors Receiving Adjuvant Chemotherapy
... had severe neutropenia (Figure ...without severe neutropenia was ...with severe neutropenia and only ...with severe neutropenia and patients without severe ...
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Severe neutropenia in a breastfed infant: a case report and discussion of the differential diagnosis
... Neonatal neutropenia is regularly seen with variable ...of severe isolated neu- ...isolated neutropenia persisted. Bone marrow aspiration indicated severe congenital ...with severe ...
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Severe neutropenia is associated with better clinical outcomes in patients with advanced pancreatic cancer who received modified FOLFIRINOX therapy
... 3-4 neutropenia showed significantly longer survival than those without severe neutropenia in the present ...study. Severe neutropenia was also a significant factor for better survival ...
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Levamisole tainted cocaine causing severe neutropenia in Alberta and British Columbia
... Despite public health notification and media interest in both provinces the true burden of NATC is likely underes- timated by voluntary reporting of NATC cases by clini- cians. As levamisole has a short half-life ...
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Clozapine-Induced Late Agranulocytosis and Severe Neutropenia Complicated with Streptococcus pneumonia, Venous Thromboembolism, and Allergic Vasculitis in Treatment-Resistant Female Psychosis
... The pathophysiologic mechanisms that produce cloza- pine-induced agranulocytosis are not well understood. There is an age-related increase in risk of 53% per decade, with adolescents having the lowest risk of ...
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Pathogenesis of ELANE mutant severe neutropenia revealed by induced pluripotent stem cells
... cyclic neutropenia, with cycles of neutropenia every 21 days ...sorting Severe congenital neutropenia (SCN) is often associated with inherited heterozygous point mutations in ELANE, which ...
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Recurrence of Neonatal Lupus Post-Cord Blood Transplant for Severe Congenital Neutropenia
... the current knowledge of NLE- associated cytopenias is based on small, outdated retrospective studies or case reports. Some case reports have described more critical manifestations such as aplastic anemia, hemorrhagic ...
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Severe congenital neutropenia due to G6PC3 deficiency: early and delayed phenotype in two patients with two novel mutations
... [4,11] severe neutropenia predisposing to severe infections is the most reliable marker of dis- ease, since congenital heart defects (mostly atrial septal defects) are present in around 80% of ...
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Plasma presepsin level is an early diagnostic marker of severe febrile neutropenia in hematologic malignancy patients
... the processed subtype presepsin has strong association with bacterial infections. Nowadays, it is well known that presepsin is a useful early diagnostic marker of sepsis. And there are reports showing its superiority to ...
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Investigation of the molecular pathogenesis of Kostmann's syndrome
... changes may be demonstrated by the use of various techniques for immunophenotyping. In the acute leukaemias prohferation and differentiation are clearly dissociated with an excess of immature undifferentiated or ...
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Primary and secondary autoimmune neutropenia
... for neutropenia in Felty’s syndrome is often the same as the patient needs for the underlying pathology, usually methotrexate [46], cyclosporine A [47], leflunomide [48] and parenteral gold ...in ...
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ANA-Negative Presentation of SLE in Man with Severe Autoimmune Neutropenia
... to severe autoimmune neutropenia only occurs in 5% of patients ...autoimmune neutropenia in SLE is ...Autoimmune neutropenia and its correlation with high anti-neutrophil antibody activity has ...
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Severe Osteopenia in a Young Boy With Kostmann’s Congenital Neutropenia Treated With Granulocyte Colony-Stimulating Factor: Suggested Therapeutic Approach
... ABSTRACT. Kostmann’s syndrome is a congenital dis- order that causes an impairment of myeloid differen- tiation in the bone marrow characterized by severe neutropenia, which can be treated with recombinant ...
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Correction of Neutropenia Associated With Dysgammaglobulinemia
... This report describes the correction of severe neutropenia in a patient with dysgammaglobulinemia type I after administration of unusually high doses of gamma- globulin. It is shown that[r] ...
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A clinical and molecular review of ubiquitous glucose-6-phosphatase deficiency caused by G6PC3mutations
... but severe neutropenia in peripheral blood (neutrophils count below ...constitutional neutropenia syndromes, no cases with myelodysplastic syndrome have been yet reported in untreated or G-CSF ...
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THE RISK FACTOR OF NEUTROPENIA ON LOCALLY ADVANCED BREAST CANCER PATIENTS TREATED WITH FIRST CYCLE CYCLOPHOSPHAMIDE, DOXORUBICINE, 5- FLUOROURACIL CHEMOTHERAPY AT SANGLAH GENERAL HOSPITAL DENPASAR, BALI-INDONESIA
... age neutropenia, presence or absence of chronic obstructive pulmonary disease, hypotension, nutritional status, hemoglobin and neutrophil ...for neutropenia followed by multivariate logistic regression ...
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ASSOCIATION OF DIHYDROPYRIMIDINE DEHYDROGENASE GENE POLYMORPHISM WITH TOXICITY OF 5 FLUROURACIL IN COLORECTAL CANCER IN KHARTOUM STATE
... The 5-fluorouracil pathway is affected by a number of genes that are known to be polymorphic, one of them is dihydropyrimidine dehydrogenase (DPYD) gene. [4] The DPYD gene is located on the short arm of chromosome 1, ...
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Description and outcome of a cohort of 8 patients with WHIM syndrome from the French Severe Chronic Neutropenia Registry
... In 1964, Zuelzer reported an exceptional congenital neu- tropenia associated with hyperplasia of mature neutrophils in the bone marrow (BM) – myelokathexis (retention of white blood cells in the BM) [1]. Its acronym ...
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Morbidity pattern and outcome of therapy in undernourished children with acute lymphoblastic leukemia
... ability. Severe decrease in peripheral blood count, marrow cellularity, stem cell content, self-renewal capacity and long term survival was seen in mice treated with drugs that are toxic for stem ...
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Late-Onset Neutropenia in Very Low Birth Weight Infants
... late-onset neutropenia occurred at postnatal age of 6 ⴞ 2 weeks (range: 3–10 ...of neutropenia was ...late-onset neutropenia were apparent in these ...
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