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Severe sepsis/septic shock

The impairment of small nerve fibers in severe sepsis and septic shock

The impairment of small nerve fibers in severe sepsis and septic shock

... Skin biopsies (Fig. 2) revealed a considerable decrease in small nerve fibers in the septic patients early in the course of disease. Eleven of the patients (34 %) showed IEFND values lower than the 0.05 quantile ...

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Cardiac Dysfunction in Patients with Sepsis, Severe Sepsis and Septic Shock

Cardiac Dysfunction in Patients with Sepsis, Severe Sepsis and Septic Shock

... with septic shock, 7 patients had ...the septic shock patients (P = ...with septic shock as compared to sepsis patients but was not significantly ...the severe ...

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The impact of smoking on patient outcomes in severe sepsis and septic shock

The impact of smoking on patient outcomes in severe sepsis and septic shock

... Sepsis is one of the most expensive conditions treated in US hospitals, and its impact on the morbidity and mor- tality of those afflicted is substantial [23]. Tobacco smoking has well-documented effects on immune ...

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Fluid Overload in Children with Severe Sepsis and Septic Shock

Fluid Overload in Children with Severe Sepsis and Septic Shock

... with severe sepsis and septic shock is one of the most useful and first-line hemodynamic treatments; but, if administered liberally, they could produce a water overload with the aforementioned ...

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Systemic inflammatory response syndrome in adult patients with nosocomial bloodstream infections due to enterococci

Systemic inflammatory response syndrome in adult patients with nosocomial bloodstream infections due to enterococci

... 52%. Septic shock occurred in 62% and severe sepsis in an additional ...to septic shock was associated with death (OR ...(severe sepsis, septic shock ...

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Epidermal wound healing in severe sepsis and septic shock in humans

Epidermal wound healing in severe sepsis and septic shock in humans

... with sepsis than in the controls [36,37]. Early sepsis is characterised by hyper-inflammation and excess of pro- inflammatory mediators such as tumour necrosis factor-alpha and interleukin-1 and ...

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Plasma protein C levels in immunocompromised septic patients are significantly lower than immunocompetent septic patients: a prospective cohort study

Plasma protein C levels in immunocompromised septic patients are significantly lower than immunocompetent septic patients: a prospective cohort study

... a septic patient is well ...in severe sepsis ...in severe sepsis (PROWESS), based on understanding of the pathophysi- ology, demonstrated a mortality benefit of APC therapy in ...

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Implementation of an Inpatient Pediatric Sepsis Identification Pathway

Implementation of an Inpatient Pediatric Sepsis Identification Pathway

... for sepsis within 12 hours after an abnormal ...with severe sepsis/septic shock were not missed by the vital sign screen, we also used EMR reports to identify all children with an EMR ...

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Expression of cell surface receptors and oxidative metabolism modulation in the clinical continuum of sepsis

Expression of cell surface receptors and oxidative metabolism modulation in the clinical continuum of sepsis

... for sepsis (14 patients), severe sep- sis (12 patients) and septic shock (15 patients) as previously described by Bone et ...or shock in sepsis, severe sepsis and ...

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TREM 1 expression on neutrophils and monocytes of septic patients: relation to the underlying infection and the implicated pathogen

TREM 1 expression on neutrophils and monocytes of septic patients: relation to the underlying infection and the implicated pathogen

... at severe sepsis who are suffering either from an intra-abdominal infection or from VAP/HAP compared with patients at sepsis suffering from similar ...at septic shock. Modulation of the ...

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Sepsis-3 definitions predict ICU mortality in a low–middle-income country

Sepsis-3 definitions predict ICU mortality in a low–middle-income country

... using sepsis, severe sepsis or septic shock as an [All field] search term in the syndromic diag- nosis fields of the ...previous Sepsis-2 ...have severe sepsis, ...

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Phosphoinositide 3 kinase gamma kinase activity significantly contributes to the pathophysiology of sepsis and multiorgan failure

Phosphoinositide 3 kinase gamma kinase activity significantly contributes to the pathophysiology of sepsis and multiorgan failure

... Methods HMGB1 and sRAGE were measured using ELISA. Results Eleven out of 16 volunteers had measurable levels of HMGB1 at baseline, before endotoxin injection. Within 2 hours of endotoxin injection, parallel to the rise ...

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Vitamin A deficiency in critically ill children with sepsis

Vitamin A deficiency in critically ill children with sepsis

... with sepsis: Pediatric Risk of Mortality (PRISM) scores (within the first 24 h of admission), temperatures, lactate levels, and basic hematological and biochemical test ...in sepsis patients, including the ...

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Plant-Powered: A Digital Plant-Based Nutrition Intervention for Low-Income Patients with Type II Diabetes

Plant-Powered: A Digital Plant-Based Nutrition Intervention for Low-Income Patients with Type II Diabetes

... for severe sepsis and septic shock for each Joint Commission-accredited hospital during its latest data collection period from 04/01/2017 - ...mandated sepsis core measure a priority ...

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Bench to bedside review: The initial hemodynamic resuscitation of the septic patient according to Surviving Sepsis Campaign guidelines – does one size fit all?

Bench to bedside review: The initial hemodynamic resuscitation of the septic patient according to Surviving Sepsis Campaign guidelines – does one size fit all?

... of severe sepsis or septic shock [10] (Table ...of sepsis which recommend filling pressures of between 12 and 15 mm Hg for the optimization of cardiac output ...and septic ...

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Outcome prediction in sepsis: Speckle tracking echocardiography based assessment of myocardial function

Outcome prediction in sepsis: Speckle tracking echocardiography based assessment of myocardial function

... with severe sepsis or septic shock admitted over an 18- month period at ...for severe sepsis or septic shock [14]. Sepsis was defined by two or more cri- ...

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CD4+ lymphocyte adenosine triphosphate determination in sepsis: a cohort study

CD4+ lymphocyte adenosine triphosphate determination in sepsis: a cohort study

... Surviving Sepsis Campaign Guidelines Committee, American Association of Critical-Care Nurses, American College of Chest Physicians, American College of Emergency Physicians, Canadian Critical Care Society, ...

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Significance of serum procalcitonin as a prognostic indicator in  patients with sirs/sepsis

Significance of serum procalcitonin as a prognostic indicator in patients with sirs/sepsis

... Severe sepsis with septic shock is a major cause of morbidity and mortality in the ...of sepsis. Clinically, once the diagnosis of sepsis is made, the prediction of survival is ...

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Sepsis and antimicrobial therapy in trauma patients

Sepsis and antimicrobial therapy in trauma patients

... in sepsis. Sepsis is a dynamic disease with progress to severe sepsis or a septic ...in sepsis is highly heterogeneous and ...

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