Shiga Toxin
A Case of a Shiga Toxin Producing Escherichia Coli
... 4. Makino S, Tobe T, Asakura H, Watarai M, Ikeda T, Takeshi K, et al. Distribution of the secondary type III secretion system locus found in enterohemorrhagic Escherichia coli O157:H7 isolates among Shiga ...
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Pathogenesis of Shigella diarrhea XVI Selective targetting of Shiga toxin to villus cells of rabbit jejunum explains the effect of the toxin on intestinal electrolyte transport
... which Shiga toxin alters intestinal water and electrolyte transport, ligated loops of rabbit jejunum were incubated in vivo with purified toxin and then studied in vivo by single pass perfusion and ...
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Comparative genomic analysis of Shiga toxin-producing and non-Shiga toxin-producing Escherichia coli O157 isolated from outbreaks in Korea
... and Shiga toxin-related genes (stx1A, 1B, 2A, and ...the toxin category, alpha-hemolysin was a main virulence gene in STEC ...38. Shiga toxin-related genes (stx1A, 1B, 2A, and 2B) [44] ...
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Simple oxidation of pyrimidinylhydrazones to triazolopyrimidines and their inhibition of Shiga toxin trafficking
... inhibiting Shiga toxin ...Golgi, Shiga toxin cannot reach the endoplasmic reticulum from where it normally translocates a membrane to reach its ribosome substrates in the ...
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Shiga Toxin, Cytolethal Distending Toxin, and Hemolysin Repertoires in Clinical Escherichia coli O91 Isolates
... Shiga toxin (Stx)-producing Escherichia coli (STEC) strains cause diarrhea and a life-threatening hemolytic-uremic syn- drome (HUS) worldwide (23, ...
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Characterization of Shiga toxin – producing Escherichia coli infections in beef feeder calves and the effectiveness of a prebiotic in alleviating Shiga toxin - producing Escherichia coli infections
... model, Shiga toxin-producing Escherichia coli (STEC) challenges result in shedding that reflect the amount of infection and the expression of virulence factors such as Shiga toxins ...
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Protection against Shiga Toxin-Producing Escherichia coli Infection by Transcutaneous Immunization with Shiga Toxin Subunit B
... The striking feature of EHEC infection is the production of potent Shiga toxins (Stx1 and/or Stx2) implicated in the devel- opment of HUS (13, 27, 28). EHEC strains are a subgroup of Shiga ...
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Comparison of a Shiga Toxin Enzyme Linked Immunosorbent Assay and Two Types of PCR for Detection of Shiga Toxin Producing Escherichia coli in Human Stool Specimens
... Shiga toxin (Stx)-producing Escherichia coli (STEC) is an emerging pathogen responsible for sporadic cases of infection as well as serious outbreaks ...
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Entry and Killing of Tetrahymena thermophila by Bacterially Produced Shiga Toxin
... IMPORTANCE Tetrahymena is a bacterial predator and a model for mammalian phagocytosis and intracellular vesicular traffick- ing. Phage-encoded exotoxins apparently have evolved for the purpose of bacterial antipredator ...
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Geographically Distinct Escherichia coli O157 Isolates Differ by Lineage, Shiga Toxin Genotype, and Total Shiga Toxin Production
... Shiga toxin production. Total Stx production was assessed using a method adapted from the work of Shringi et al. (21). Specifically, over- night cultures were prepared with a single colony in 5 ml sterile ...
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Real Time Fluorescence PCR Assays for Detection and Characterization of Shiga Toxin, Intimin, and Enterohemolysin Genes from Shiga Toxin Producing Escherichia coli
... Shiga toxin-producing Escherichia coli (STEC) strains, also referred to as verocytotoxin-producing ...the toxin genes, PCR assays have been used widely to detect small numbers of STEC present in ...
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A Poly N Acetylglucosamine−Shiga Toxin Broad Spectrum Conjugate Vaccine for Shiga Toxin Producing Escherichia coli
... as Shiga toxin (Stx)-producing Escherichia coli (STEC), an important group of gastrointestinal (GI) pathogens for which effective immuno- therapeutics are ...the Shiga toxin 1b subunit (9GlcNH ...
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Subtyping Method for Escherichia coli Shiga Toxin (Verocytotoxin) 2 Variants and Correlations to Clinical Manifestations
... by Shiga toxin-producing Escherichia coli (STEC), alternatively known as verocytotoxin-produc- ing ...produce Shiga toxins (Stx or verocytotoxin) 1 and 2, which are two sequen- tially and ...
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A Rapid Immunoassay for Detection of Shiga Toxin Producing Escherichia coli Directly from Human Fecal Samples and Its Performance in Detection of Toxin Subtypes
... procedure. Toxin production was confirmed by Vero cell cytotox- icity assay (33), and positive samples were neutralized with specific rabbit antisera against Stx1 and Stx2 (TechLab, ...The Shiga ...
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Promoter Sequence of Shiga Toxin 2 (Stx2) Is Recognized In Vivo, Leading to Production of Biologically Active Stx2
... Enterohemorrhagic Shiga toxin (Stx)-producing Escherichia coli (EHEC) infections are a serious public health problem, and Stx is the main pathogenic agent associated with typical hemolytic-uremic syndrome ...
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Serogroups, virulence genes and antibiotic resistance in Shiga toxin-producing Escherichia coli isolated from diarrheic and non-diarrheic pediatric patients in Iran
... 8.33% of 37–48 month-old diarrheic, 11.76% of 25–36 month-old diarrheic, 10.25% of 13–24 month-old diar- rheic and 8.33% of 1–12 month-old diarrheic patients harbored stx1 , stx2 and eaeA genes. Similar findings have ...
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Evaluation of Enzyme Immunoassays and Real Time PCR for Detecting Shiga Toxin Producing Escherichia coli in Southern Alberta, Canada
... Using Shiga Toxin Chek on stool samples, the sensitivity and specificity were ...The Shiga Toxin Quik Chek performed similarly to the Shiga Toxin Chek in stool samples but with a ...
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Bacteriophage-encoded shiga toxin gene in atypical bacterial host
... diphtheria toxin and was responsible for the virulence traits of ...the shiga toxin (stx) gene of Escherichia coli O157:H7 species, the cho- lera toxin gene (ctx) carried by ctx j of Vibrio ...
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9-2-2015 12:00 AM A Plant-Made Vaccine Candidate To Protect Ruminants Against Shiga Toxin-Producing Escherichia Coli
... Several Shiga toxin-producing ...the Shiga toxin is also a potential vaccine antigen as Stx2 promotes STEC colonization in cattle intestine (Baines et ...
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Detection of Shiga toxin producing Shigella dysenteriae type 1 and Escherichia coli by using polymerase chain reaction with incorporation of digoxigenin 11 dUTP
... A technique has been developed for the detection of Shiga toxin- and Shiga-like toxin type I ShT/SLT-Iproducing Shigella dysenteriae type 1 and Escherichia coli by using the polymerase c[r] ...
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