Short-acting beta-2 agonists
High oral corticosteroid exposure and overuse of short-acting beta-2-agonists were associated with insufficient prescribing of controller medication: a nationwide electronic prescribing and dispensing database analysis
... The over-prescription of SABA with insufficient con- troller medication prescription remains frequent. In a 1-year study on asthma patients from primary care healthcare records, 6.6% of the SABA over-users were not on ...
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1. Beta2-adrenoceptor agonists a. Short-acting: To prevent/treat wheezing/coughing acutely. 2. Anticholinergic (muscarinic) drugs
... • No daily medications, only as needed to relieve symptoms with inhaled short-acting beta-2 agonists (quick relief/rescue).. • Intensity of treatment depends on severity![r] ...
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Role of indacaterol and the newer very long-acting β2-agonists in patients with stable COPD: a review
... as short-acting β 2-agonists on the first day of use, 42 and this favors patient recognition of ...β 2-agonists, once-daily dos- ing of a VLABA appears to be more convenient for ...
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Hospital readmissions following initiation of nebulized arformoterol tartrate or nebulized short-acting beta-agonists among inpatients treated for COPD
... Patients with COPD discharge diagnoses in the hospital were assumed to have met formal COPD diagnostic criteria, but no spirometry results were available to confirm the diagnoses. Although the analyses controlled for a ...
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Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis.
... regular short-acting medications for patients with exacerbations or persistent breath- lessness (NICE 2011), otherwise referred to as those with moder- ate (stage II) or severe (stage III) COPD ...fell ...
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Long-acting beta-agonists in the management of chronic obstructive pulmonary disease: current and future agents
... b 2 - agonist; LAMA: Long-acting Muscarinic Antagonists; MCID: Minimal Clinically Important Difference; MDI: Metered-dose Inhaler; SABA: Short-acting b 2 - agonist; SAMA: ...
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Once-daily long-acting beta-agonists for chronic obstructive pulmonary disease: an indirect comparison of olodaterol and indacaterol
... An important difference among the studies included in the evidence base is whether concomitant use of noninvestiga- tional COPD treatments was permitted in the trials by design. Specifically, the olodaterol trials ...
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Comparative study of inhaled steroids versus inhaled steroids plus long acting beta agonists in childhood asthma: a randomized controlled study
... Salmeterol and formoterol are highly selective, third generation LABAs that have been available for use since the early 1990s. Salmeterol and formoterol, however, differ in their pharmacological properties. One important ...
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Indacaterol: a new once daily long-acting beta<sub>2</sub> adrenoceptor agonist
... daily beta 2 agonists, formoterol and salmeterol, and the once daily anticholinergic, ...to short-acting agents with multiple daily ...daily beta 2 agonist as compared to ...
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Bronchodilators in COPD: Impact of β-agonists and anticholinergics on severe exacerbations and mortality
... It is unfortunate that there was not enough information to evaluate the protective effect of concomitant inhaled corticosteroids on the adverse effects of β -agonists. Furthermore, it was not possible to perform ...
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Prescribing of long-acting beta-2-agonists/inhaled corticosteroids after the SMART trial
... Background The Salmeterol Multicentre Asthma Research Trial (SMART) [1] was a large randomized controlled trial in asthma patients evaluating the safety of salmeterol (i.e., a long-acting ...
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Tolerance to bronchodilation during treatment with long-acting beta-agonists, a randomised controlled trial
... no beta-ago- nists were used, subjects were computer randomised to receive coded bottles of capsules containing formoterol 12 µ g or matching placebo for use with the Foradil aerolizer device (Foradil, Novartis, ...
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The effect of adding inhaled corticosteroids to tiotropium and long-acting beta(2)-agonists for chronic obstructive pulmonary disease (Review)
... long-acting beta 2 - agonist (LABA) Inhaled beta 2 -agonists activate beta 2 -receptors in the smooth mus- cle of the airway leading to a cascade of reactions that ...
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Comparative efficacy of long-acting β2-agonists as monotherapy for chronic obstructive pulmonary disease: a network meta-analysis
... Future prospective studies evaluating the thresholds for clinically meaningful differences between active treatments in COPD therapy trials are needed. The results of this study add to and update the pre-existing ...
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The effect of adding inhaled corticosteroids to tiotropium and long-acting beta 2 -agonists for chronic obstructive pulmonary disease (Review)
... long-acting beta 2 - agonist (LABA) Inhaled beta 2 -agonists activate beta 2 -receptors in the smooth mus- cle of the airway leading to a cascade of reactions that ...
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Short-acting β2-agonists (SABA) bronchodilator sales and outdoor mould in central France
... Martin 2 , C. Ségala 2 , ...of short-acting β2-agonists (SABA), a specific and frequent treatment for control of mild asthma exacerba- tions in children and young adults, and outdoor ...
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Efficacy and safety of the CRTh2 antagonist AZD1981 as add-on therapy to inhaled corticosteroids and long-acting β2-agonists in patients with atopic asthma
... group 2 innate lymphoid cells (ILC2s), 6 and CRTh2 is activated by the proinflammatory mediator prostaglandin D 2 (PGD 2 ...PGD 2 is a major arachi- donic acid metabolite released by airway ...
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The impact of acute and chronic administration of short-acting β2-agonists on urinary pharmacokinetics and athletic performance
... β 2 -agonists in sporting competition has been a constant matter of debate for doping ...β 2 -agonist salbutamol at therapeutic doses has so far been unable to ascertain any performance enhancing ...
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Do beta –2 Agonists reduce Admission rate in children with bronchiolitis?
... within 2-4 days, this virus mainly affects the distal part of the respiratory tract (bronchioles), which results in direct damage to epithelial surface in the small airway and indirect damage to the respiratory ...
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<p>Comparative Effectiveness of Long-Acting GLP-1 Receptor Agonists in Type 2 Diabetes: A Short Review on the Emerging Data</p>
... Albiglutide has not been directly compared with either semaglutide or dulaglutide but was assessed versus once- daily liraglutide in the HARMONY 7 trial. 17 Comparison with liraglutide is of interest since this agent was ...
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