SHR=spontaneously hypertensive rat
Association of chronic diabetes and hypertension in sural nerve morphometry: an experimental study
... the SHR + STZ, this number was reduced compared to ...in SHR, with or without ...Wistar rat control group (WR), normotensive Wistar rat chronically induced diabetes group (WR + STZ), ...
9
Behavioural effects of methylphenidate in the spontaneously hypertensive rat model of attention-deficit/hyperactivity disorder: a systematic review and meta-analysis protocol
... the SHR when compared with placebo? In order to achieve this aim, the following objectives were defined: (1) conduct an exten- sive literature research in order to select all studies eval- uating the behavioural ...
5
In vivo assessment of arterial stiffness in the isoflurane anesthetized spontaneously hypertensive rat
... To assess intra- and inter-observer variability of wave propagation time, the intervals between the R-wave of the EKG to the foot of the Doppler carotid and iliac wave- forms were re-measured in a randomly selected ...
8
Original Article Chaihu Shugan Powder attenuates Liver Qi stagnation type of metabolic syndrome in spontaneously hypertensive rats by upregulating liver X receptor-alpha
... Stagnation rat model and to observe the effects of Chaihu Shugan Powder on the main components of MetS and the expression of LXR mRNA in the liver ...in spontaneously hypertensive rats (SHR) ...
8
Hypertension effects on p73 expression in the rat circumventricular organs and cerebrospinal fluid
... that spontaneously hypertensive rats (SHR) show ventricular dilation, changes in CSF proteins and variations in the circumventricular organs (CVO) such as: the subcommissural organ (SCO), the ...
6
Original Article Notoginsenoside R1 reduces blood pressure in spontaneously hypertensive rats through a long non-coding RNA AK094457
... We used the Arraystar Human LncRNA Array v2.0, submitted to the Gene Expression Omnibus (GEO) by Varambally at Sep 17, 2005 and last update at Nov 26, 2014, to analyze dif- ferential LncRNAs expression between hyper- ...
10
Cardiac remodeling and myocardial dysfunction in obese spontaneously hypertensive rats
... In SHR-ob, cardiac protein expression of GLUT1 was increased compared to SHR-lean and normotensive con- ...in SHR-ob suggests an upregulation of GLUT1/ANF-axis being in agreement with the concept of ...
10
Cardiopulmonary responses of Wistar Kyoto (WKY), spontaneously hypertensive rats (SHR) and stroke prone SHR (SHRSP) to particulate matter (PM) exposure
... The selection of exposure dose and method is guided by the hypothesis being evaluated. Ideally, exposures should mimic real world exposures-in this case, long term inhalation of PM at low concentrations. However, it is ...
83
Cerebrospinal fluid is drained primarily via the spinal canal and olfactory route in young and aged spontaneously hypertensive rats
... entire rat brain we developed a novel contrast-enhanced computed tomography (CT) technique to image the rat CSF system in ...aged spontaneously hypertensive rats (SHR) because their ...
9
Role of Nitric Oxide, Produced by nNOS in the Regulation of Water and Electrolyte Excretion in Spontaneously Hypertensive Rats
... male SHR, 12 – 14 weeks old, weighing 280–300 ...and rat chow were provided ad libitum. The SHR group consisted of rats with systolic arterial blood pressure over 170 mmHg previously measured by tile ...
7
Instrumental conditioning for food reinforcement in the spontaneously hypertensive rat model of attention deficit hyperactivity disorder
... the SHR. Previous work has indicated that the SHR do display an increased stress response ...the SHR has an active response to stress [87] and altered escape behaviour ...the SHR at being ...
17
Heterozygous connexin 50 mutation affects metabolic syndrome attributes in spontaneously hypertensive rat
... in spontaneously hypertensive rat strain (SHR hereafter; Rat Genome Database (RGD) [8] ID: 631848) leads to microphthalmia and cataract ...strain SHR-Gja8 ...
9
EXPRESSION OF VASCULAR ENDOTHELIAL GROWTH FACTOR A AND ITS RECEPTORS IN UTEROPLACENTAL TISSUES OF THE NORMOTENSIVE AND HYPERTENSIVE PREGNANT RAT
... normal rat uteroplacental tissues at early, mid and late ...the spontaneously hypertensive rat (SHR) at 7, 11 and 19 days of ...gestation. Spontaneously hypertensive rats ...
197
Role of the D1A dopamine receptor in the pathogenesis of genetic hypertension
... the spontaneously hypertensive rat (SHR), in spite of normal renal production of dopamine and receptor density, there is defective transduction of the D1 receptor signal in renal proximal ...
7
ANTIHYPERTENSIVE AND LIPID LOWERING EFFECT OF TERMINALIA ARJUNA (AQUEOUS EXTRACT) IN SPONTANEOUSLY HYPERTENSIVE RATS (SHR): AN EXPERIMENTAL STUDY
... Essential hypertension, accounting for 90 percent of all cases of hypertension, is the leading member of the so called non communicable diseases and one of the leading causes of death in developed as well as developing ...
8
Erythrocytosis in Spontaneously Hypertensive Rats
... A significant increase in red cell count was observed in spontaneously hypertensive SH rats 8-11 × 106 RBC/mm3 when compared with normotensive rats 6-7 × 106 RBC/mm3 of the same strain..[r] ...
6
Role of the Renal Sympathetic Nerves in the Development and Maintenance of Hypertension in the Spontaneously Hypertensive Rat
... the spontaneously hypertensive rat of the Okamoto ...(early hypertensive) and 18-wk-old (established hypertensive) male spontaneously hypertensive rats were subjected to ...
9
A gene differentially expressed in the kidney of the spontaneously hypertensive rat cosegregates with increased blood pressure
... the spontaneously hypertensive rat, cosegregates with an increase in blood pressure in F2 rats derived from a cross of the spontaneously hypertensive rat with normotensive ...
6
Mapping of quantitative trait loci for blood pressure and cardiac mass in the rat by genome scanning of recombinant inbred strains
... systolic, diastolic, and mean arterial pressure were D19Mit7 on chromosome 19 (P = .0012, r = .55), D2N35 on chromosome 2 (P = .0008, r = .56), and Il6 on chromosome 4 (P = .0018, r = .53), respectively. These studies ...
7
Mechanisms of the anti hypertensive effect of Hibiscus sabdariffa L calyces
... High K + and PE-induced increases in aortic tone by stimulating Ca 2+ influx through voltage and receptor oper- ated Ca 2+ channels (Bolton, 1979; Karaki and Weiss, 1984). The present results demonstrated that HSE ...
6