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Sickle cell disease therapy

Effectiveness of Hydroxyurea Therapy in Sickle Cell Disease and Sickle Cell Trait

Effectiveness of Hydroxyurea Therapy in Sickle Cell Disease and Sickle Cell Trait

... of sickle cell disease (36 homozygous and 9 ...in sickle-cell opd for compliance, effectiveness and adverse ...hydroxyurea therapy, baseline investigations and HPLC were ...of ...

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The role of the arginine metabolome in pain: implications for sickle cell disease

The role of the arginine metabolome in pain: implications for sickle cell disease

... Notes: (A) Arginine supplementation (unfilled circles) led to a significant and clinically relevant reduction in total opioid use by 54% over the course of the hospital stay compared to total opioid use in the placebo ...

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Uncovering How Occupational Therapy Could Benefit Individuals Living with Sickle Cell Disease in Ghana, Carolyn D'Olympio

Uncovering How Occupational Therapy Could Benefit Individuals Living with Sickle Cell Disease in Ghana, Carolyn D'Olympio

... occupational therapy evaluations during naturally occurring ...occupational therapy students from UNH led to a new occupational therapy assessment tool now used ...with sickle cell ...

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Genetic polymorphisms linked to susceptibility to malaria

Genetic polymorphisms linked to susceptibility to malaria

... up sickle cell trait as a bench mark reference protective factor, utility of these studies in understanding genes associated with malaria severity continues to be limited to identifying only broad asso- ...

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Retinopathy Revealing Cerebral Venous Thrombosis in Sickle Cell Disease in Niger

Retinopathy Revealing Cerebral Venous Thrombosis in Sickle Cell Disease in Niger

... in sickle cell disease has been rarely de- scribed in the ...consider sickle cell disease as a risk factor for ...as sickle cell, followed at the National Reference ...

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Study of clinical profile of painful crisis in hospitalized children of sickle cell anemia

Study of clinical profile of painful crisis in hospitalized children of sickle cell anemia

... hydroxyurea therapy due to financial ...of Sickle cell disease in Central India and high burden of morbidity and mortality due to Sickle cell disease it is recommended to ...

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Comparative Study between Cholecystectomy in Sickle Cell Patients and Non Sickle Cell Patients

Comparative Study between Cholecystectomy in Sickle Cell Patients and Non Sickle Cell Patients

... of sickle cell patients was carried out by the doctors of the Anesthesia-Resuscitation Department, the Center for Research and Control of Sickle Cell Disease (CRLD) and the Surgical ...

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SICKLE CELL ANEMIA DISEASE TREATMENT BY BLOOD TRANSFUSION

SICKLE CELL ANEMIA DISEASE TREATMENT BY BLOOD TRANSFUSION

... Transfusion therapy leads to major enhancement in blood viscosity, red cell deformability, and red cell accumulation, but there may be major rheologic and physiologic differences between simple ...

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Current challenges in the management of patients with sickle cell disease – A report of the Italian experience

Current challenges in the management of patients with sickle cell disease – A report of the Italian experience

... erythrocytapheresis (initiated at 10.7 ± 5.2 weeks of gestation) improved maternal and fetal outcomes in SCD women with a history of severe SCD-related organ complications [53]. The generation of SITE recommen- dations ...

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Health-related quality of life of adolescents with sickle cell disease in sub-Saharan Africa: a cross-sectional study

Health-related quality of life of adolescents with sickle cell disease in sub-Saharan Africa: a cross-sectional study

... Hydroxyurea therapy re- ported better physical functioning and overall HRQoL than those not taking the medication despite disease severity and older age ...

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Static and dynamic rigidities of normal and sickle erythrocytes  Major influence of cell hemoglobin concentration

Static and dynamic rigidities of normal and sickle erythrocytes Major influence of cell hemoglobin concentration

... of sickle cells increased with increasing cell hemoglobin concentration while that of normal cells was independent of the state of cell ...Moreover, sickle cells were found to exhibit ...

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Growth and metabolism in homozygous sickle cell disease

Growth and metabolism in homozygous sickle cell disease

... There is a dearth of formal dietary information in SS disease. Published data suggest that energy intake in SS patients is similar to that of AA controls (Phebus et al, 1988, Tangney et al, 1989). However, these ...

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“HÉMODYA”: A PHYTOMEDECINE FOR SICKLE CELL DISEASE MANAGEMENT IN CAMEROON

“HÉMODYA”: A PHYTOMEDECINE FOR SICKLE CELL DISEASE MANAGEMENT IN CAMEROON

... The present study, evaluates the role of “hémodya” as a phytomedicine in the management of sickle cell disease. The phenolic content, free radical, and reactive oxygen scavenging ability of “hémodya” ...

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Clinical utility of carotid and transcranial ultrasound in cerebrovascular diseases

Clinical utility of carotid and transcranial ultrasound in cerebrovascular diseases

... Abstract: Carotid and transcranial (CTU) ultrasound is a useful tool in a number of clinical settings, particularly in cerebrovascular diseases. CTU is the only method that provides real-time determination of velocity ...

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Original Research Article A study on C-reactive protein as an early marker of vasococclusive crisis in homozygous sickle cell disease (HbSS) and sickle cell- thalassemia disease (Hb S- thal)

Original Research Article A study on C-reactive protein as an early marker of vasococclusive crisis in homozygous sickle cell disease (HbSS) and sickle cell- thalassemia disease (Hb S- thal)

... Although the sickling test and haemoglobin solubility test detect the presence of HbS, haemoglobin electrophoresis is mandatory for precise diagnosis of sickle haemoglobinopathies. The principle of ...

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Amelioration of Sickle Cell Pain after Parathyroidectomy in Two Patients with Concurrent Hyperparathyroidism: An Interesting Finding

Amelioration of Sickle Cell Pain after Parathyroidectomy in Two Patients with Concurrent Hyperparathyroidism: An Interesting Finding

... Sickle cell disease (SCD) is a genetic disorder which affects approximately 100,000 Americans ...This disease is char- acterized by production of an abnormal hemoglobin (Hb) molecule which ...

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The Warped One: Nationalist Adaptations of the Cuchulain Myth

The Warped One: Nationalist Adaptations of the Cuchulain Myth

... Sickle cell disease (SCD) is a genetic blood disorder that can adversely affect the physical and psychosocial wellbeing of those with the disease, including elevated rates of internalizing ...

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Significant Reduction of Vitamin B12 Levels in Sudanese Sickle Cell Disease Patients

Significant Reduction of Vitamin B12 Levels in Sudanese Sickle Cell Disease Patients

... Result: In this study the mean of serum Cobalamin in the sickle cell patients was statistically significantly lower compared with the normal non-sickle cell disease group with p value = [r] ...

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ANESTHETIC RISKS IN SICKLE CELL TRAIT

ANESTHETIC RISKS IN SICKLE CELL TRAIT

... Most clinical disease associated with sick- ling of red blood cells has been described in sickle cell anemia ( S-S hemoglobinopathy),. sickle cell-hemoglobin C disease ( S-C hemo-[r] ...

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The financial burden of sickle cell disease among parents of children with sickle cell disease in Lagos, Nigeria

The financial burden of sickle cell disease among parents of children with sickle cell disease in Lagos, Nigeria

... with sickle cell disease have been hospitalized in the last one year and most for about one week, with an average hospital bill of about N30, ...

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