Site selective
Protecting group free site selective reactions in a metal–organic framework reaction vessel
... the site isolation ...the site-selective conversion of dialkynes into alkyne-substi- tuted triazoles when the structure metrics of the dialkyne are smaller than the azide group spacing in the ...
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Atomistic Analyses of Competition between Site Selective Segregation and Association of Point Defects at Grain Boundary in Y2O3 Doped ZrO2
... most of anion sites within ³5 ¡ of the GB plane. Although this trend may not be called as “site-selective occupation”, we conclude that an isolated V €O also has the significant driving force for segregation ...
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Palladium-unleashed proteins: gentle aldehyde decaging for site-selective protein modification
... Protein bioconjugation frequently makes use of aldehydes as reac- tive handles, with methods for their installation being highly valued. Here a new, powerful strategy to unmask a reactive protein aldehyde is presented. A ...
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Influence of hole shape/size on the growth of site selective quantum dots
... QD nucleation can be controlled by several methods. In prior works, we investigated the influence of hole spac- ing and post-growth annealing [23,24]. It was also shown by other groups that growth parameters like flux ...
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Site-selective deuteration of N-heterocycles via iridium-catalyzed hydrogen isotope exchange
... To understand the origins of this notable selectivity, the reaction was studied computationally, in order to establish the relative energies of binding and C − H activation for each of the possible labeling sites. In ...
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Site selective real-time measurements of atmospheric N 2O isotopomers by laser spectroscopy
... is laboratory-based isotope-ratio mass-spectrometry (IRMS) in combination with flask-sampling (Brenninkmeijer and R¨ockmann, 1999; Toyoda and Yoshida, 1999). It is a well- known method with excellent precision of up to ...
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Site selective substitutional doping with atomic precision on stepped Al (111) surface by single atom manipulation
... We also try other approaches to position the dopant. For instance, when the tip reaches 7.1 Å, we withdraw the tip vertically in the Z direction instead of moving the tip laterally in the X direction. For the Ag dopant, ...
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Iridium-catalyzed formyl-selective deuteration of aldehydes
... also be employed in a one-pot process leading to derivatization of the labeled formyl moiety. DFT analysis supports competition between an Ir(III) catalytic cycle for aryl labelling, and previously unreported ...
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Na_unc_0153D_19300.pdf
... of site- selective C–H oxidations, halogenations, and azidations, with practical applications in the late- stage derivatization of natural products and drug derivatives (see Chapter ...
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Development of artificial metalloenzymes via covalent modification of proteins
... covalent, site-selective introduction of a phosphane-ligand is the aforementioned modification of the active site serine of a lipase with a diphosphane coupled to a phosphonate ...covalent, ...
227
Anti-Angiogenesis Therapy in the Vx2 Rabbit Cancer Model with a Lipase-cleavable Sn 2 Taxane Phospholipid Prodrug using αvβ3-Targeted Theranostic Nanoparticles
... Docetaxel (AvaChem Scientific), a clinically rel- evant broad-spectrum anticancer agent, was utilized in the present study for site-specific anti-angiogenesis therapy. Docetaxel has a low solubility in water ...
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Tunable Pt nanocatalysts for the aerobic selox of cinnamyl alcohol
... Selective oxidation activity scales with Pt dispersion in the order KIT-6 ≥ SBA-15 > SiO2, evidencing surface PtO2 as the active site for cinnamyl alcohol selox to cinnamaldehyde.. Kinet[r] ...
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De-intensification of adjuvant therapy in human papillomavirus-associated oropharyngeal cancer
... Of note, while in theory eliminating the primary tumor bed as a target would theoretically lead to a substantial decrease in radiation to normal tissues, dosimetric stud- ies comparing primary plus neck irradiation with ...
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Enzymes in lipid modification: From classical biocatalysis with commercial enzymes to advanced protein engineering tools
... butanol (Borgdorf and Warwel, 1999). After we could establish functional expression of CAL-A in E. coli, we performed computer modeling based on the 3D-structure of the lipase and inspected all residues comprising the 30 ...
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Biphasic effects of losartan potassium on immobility in mice
... However, the selectivity is not absolute, and large concentrations of AT1 selective receptor antagonists can displace Ang II from AT1 receptors to the alternative site AT2 receptors.26 [r] ...
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Gadolinium enhanced nerve roots in lumbar disk herniation
... The selective enhancement of intradural roots, affected with corresponding L5-S 1 disk herniation arrowh ead, is seen extending from the site of compression arrows, G along their whole l[r] ...
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Selective Binding Site for [3H]Prostacyclin on Platelets
... capacity of 2,700±700 sites per platelet. The relative ability of PGI 2 , PGE 1 , PGE 2 , and 6- keto-PGF 1a to displace [ 3 H]PGI 2 initially bound to the higher affinity class of sites were 100:5:<0.3: <0.3. ...
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Site specific chromatin immunoprecipitation: a selective method to individually analyze neighboring transcription factor binding sites in vivo
... this site-specific ChIP, we were able to confirm four previously described Sp1 binding sites within egfr promoter region to be occupied by Sp1 in ...this site-specific ChIP could be demonstrated by ...
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Adapt Globally, Act Locally: The Effect of Selective Sweeps on Bacterial Sequence Diversity
... the selective sweep rate sequence-similarity cluster, as described in cases 1 is complete in population 2, most of the diversity at the B and 2 above (Cohan 1994a, 1995; Palys et ...the selective sweep ...
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A Novel Aluminum (III)-selective PVC Membrane Electrode Based on a Schiff Base Complex of bis(5-sulphonate salicylaldehyde) 2,3-diaminobenzene
... Ion selective electrode with its excellent features is widely used to determine many elements in real ...Ion selective electrode includes many parts, in which the neutral carrier is playing the most ...
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