SK-N-SH Cells
Pro-inflammatory cytokines derived from West Nile virus (WNV)-infected SK-N-SH cells mediate neuroinflammatory markers and neuronal death
... infected SK-N-SH cells with cell toxicity (Figures 1 and 2), we next investigated the effect of these cytokines by using specific neutralizing antibodies against these cyto- ...positive ...
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Curcumin Attenuates Hydrogen Peroxide-Induced Cytotoxicity in Human Neuroblastoma SK-N-SH Cells
... 25,000 cells were cultured in each well of a 96-well plate and incubated ...The SK-N-SH cells were kept in a 37 ˚ C incubator with 5% CO 2 for an ...
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Protective Effects of Pre-Germinated Brown Rice Extract against Amyloid β-Peptide Induced Neurotoxicity in Neuronal SK-N-SH Cells
... neuronal SK-N-SH ...of cells viability had no significantly different to decrease. The cells survival were up to ...neuronal SK-N-SH cells (Figure ...
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Glycoprotein D or J Delivered in transBlocks Apoptosis in SK-N-SH Cells Induced by a Herpes Simplex Virus 1 Mutant Lacking Intact Genes Expressing Both Glycoproteins
... The third potential mechanism may involve interaction of gD, modified by addition of mannose-phosphate with one of the two mannose-phosphate receptors. It has been reported that during productive infection, a small ...
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Original Article Identification of genes involved in enterovirus 71 infected SK-N-SH cells
... Labeled cDNA was prepared from the different RNA samples and then hybridized to cDNA microarrays as instruction of Beijing Boao Company. The area of a gene filter is displayed in Figure 2 and showing several genes were ...
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Arsenic trioxide induces cell cycle arrest and affects Trk receptor expression in human neuroblastoma SK-N-SH cells
... Results: Immunohistochemical and real-time PCR analyses indicated that TrkA and TrkC were over-expressed in NB, and specifically during stages 1, 2 and 4S of the disease progression. TrkB expression was increased in ...
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Ataxia-telangiectasia mutated ( ATM ) silencing promotes neuroblastoma progression through a MYCN independent mechanism
... on SK-N-SH or CLB-Ga cells do not appear to require ...in SK-N-SH cells stably transfected with ATM shRNA vectors 3650 or with LacZ shRNA ...for N-myc or ...
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Changes in cytokine and chemokine profiles in mouse serum and brain, and in human neural cells, upon tick-borne encephalitis virus infection
... TBEV-infected SK-N-SH cells influ- enced naïve ...neuroblastoma cells did not increase the production of any of the analyzed soluble ...fected SK-N-SH can activate ...
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Suppression of the phenotype of gamma(1)34.5- herpes simplex virus 1: failure of activated RNA-dependent protein kinase to shut off protein synthesis is associated with a deletion in the domain of the alpha47 gene.
... neuroblastoma SK-N-SH cell lines used were obtained from the American Type Culture ...lung cells were the kind gift of ...The cells were propagated in Dulbecco’s modified Eagle’s medium ...
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Nanoformulated cell-penetrating survivin mutant and its dual actions
... cancerous SK-N-SH neuroblastoma cell lines and differentiated SK-N-SH ...cancerous cells and proliferative toward the differentiated ...(undifferentiated ...
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Piperine induces autophagy by enhancing protein phosphotase 2A activity in a rotenone-induced Parkinson’s disease model
... protected SK- N-SH cells and primary neurons against mitochondrial damage resulting from rotenone treatment by activating autophagy via inhibition of AKT-mTORC1 signaling, with PP2A mediating ...
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Long noncoding RNA DLX6-AS1 promotes neuroblastoma progression by regulating miR-107/BDNF pathway
... Lentivirus expressing shDLX6-AS1 or shRNA control were designed and packaged by Genechem (Shanghai, China). Stable cell lines were established by infecting lentivirus into SK-N-SH cells and ...
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The Effects of Boswellia Resin Extract on Dopaminergic Cell line, SK-N-SH, against MPP+-Induced Neurotoxicity
... of SK-N-SH cell-line to oxidative stress, acti- vates caspase 3 and 9 and results in significant increase in number of apoptotic cells (Baratchi, Kanwar, & Kan- war, ...of ...
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Enterovirus 71-induced autophagy increases viral replication and pathogenesis in a suckling mouse model
... neuronal SK-N-SH cells induces an autophagic ...EV71-infected SK-N-SH cells, EV71 structural protein VP1 and nonstructural protein 2C co-localized with LC3 and ...
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Autophagic flux induced by graphene oxide has a neuroprotective effect against human prion protein fragments
... (106–126)-treated cells. (A) sK-N-sh cells were treated with gO (8 mg/l, 12 h) with or without cQ (10 µM, 12 h) and then exposed to 50 µM of PrP (106–126) for 24 ...(D) ...
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Dynasore Disrupts Trafficking of Herpes Simplex Virus Proteins
... neuronal cells were infected with HSV-1(KVP26GFP) (10 PFU/cell) for 1 h at ...and cells were trypsinized and cocultured on a layer of untreated CaSki cells ( ⬃ 90% confluence) on glass coverslips at ...
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Antioxidative and Neuroprotective Activities of the Pre Germinated Brown Rice Extract
... neuronal SK-N-SH cells was ...to SK-N-SH cells for 24 ...of cells survival showed that ...viability cells had no significantly decrease cell survivals ...
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Neuroprotection via RNA-binding protein RBM3 expression is regulated by hypothermia but not by hypoxia in human SK-N-SH neurons
... in SK-N- SH cells that were exposed to hypoxia or 8% O 2 concentra- tion for 24 hours before induction of hypothermia, as well as in the cells that were kept under atmospheric normoxia ...
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The Domains of Glycoprotein D Required To Block Apoptosis Depend on Whether Glycoprotein D Is Present in the Virions Carrying Herpes Simplex Virus 1 Genome Lacking the Gene Encoding the Glycoprotein
... viruses. SK-N-SH cells were obtained from the American Type Culture Collection (Rockville, ...HEp-2 cells than those of gD⫺/⫹ ...
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Cation-Independent Mannose 6-Phosphate Receptor Blocks Apoptosis Induced by Herpes Simplex Virus 1 Mutants Lacking Glycoprotein D and Is Likely the Target of Antiapoptotic Activity of the Glycoprotein
... experiments, SK-N-SH cells were infected with 10 PFU of a recombinant baculovirus carrying the CI-MPR gene in the antisense ...from cells harvested 24 h after infection and processed by ...
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