skin inflammation
Activated macrophages are essential in a murine model for T cell–mediated chronic psoriasiform skin inflammation
... form skin inflammation and is accompanied by reduced numbers of mac- rophages and decreased expression of MHC class II molecules and ...psoriasiform skin disease in our mouse ...
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IL 21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice
... examined skin lesions from patients with AD and used a mouse model of allergic skin ...acute skin lesions of AD patients and in mouse skin subjected to tape stripping, a surrogate for ...
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Comprehensive, Multimodal Characterization of an Imiquimod-Induced Human Skin Inflammation Model for Drug Development
... human skin inflammation model with IMQ for application in clinical drug ...intact skin (n = 8) or tape stripped (TS) skin (n = ...IMQ skin inflammation challenge model was ...
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Antibody-mediated delivery of VEGF-C potently reduces chronic skin inflammation
... with skin blood vessels being the least ...the skin do not display changes in the blood vasculature ...alleviated skin inflammation in mouse models of psoriasis (34, ...
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Combined deletion of p38γ and p38δ reduces skin inflammation and protects from carcinogenesis
... chronic skin inflammation to the development of squamous cell carcinoma (SCC) is poorly ...blocked skin tumour development in a chemically induced carcinogenesis ...and inflammation; it ...
16
Chronic skin inflammation accelerates macrophage cholesterol crystal formation and atherosclerosis
... systemic inflammation, dyslipidemia, and cardiometabolic ...chronic inflammation and that skin inflammation induces a proatherosclerotic macrophage phenotype with impaired SOD2 function, which ...
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CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation
... allergic skin inflammation induced by repeated epicutaneous sensitization with ovalbumin (OVA), and characterized by eosinophil skin infiltration, local expression of Th2 cytokines, and airway ...
9
Salidroside suppresses solar ultraviolet-induced skin inflammation by targeting cyclooxygenase-2
... causes skin disorders such as inflammation, photoaging, and ...induced skin inflammation, and targeting COX-2 may be a strategy to prevent skin ...human skin keratinocyte HaCaT ...
12
CD1b autoreactive T cells contribute to hyperlipidemia induced skin inflammation in mice
... We detected a higher frequency of CD1a- and CD1b-restrict- ed T cells in the blood of psoriatic patients compared with nor- mal individuals. Even though it is currently unknown whether psoriasis leads to hyperlipidemia ...
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A distinct bacterial dysbiosis associated skin inflammation in ovine footrot
... Ovine footrot is a highly prevalent bacterial disease caused by Dichelobacter nodosus and characterised by the separation of the hoof horn from the underlying skin. The role of innate immune molecules and other ...
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Multi-walled carbon nanotube oxidation dependent keratinocyte cytotoxicity and skin inflammation
... effect of these MWCNTs on normal and inflamed skin, our lab uses hairless C57BL/6 mice treated with either vehicle or a DNFB sensitizer. As we have previously re- ported, topically applied MWCNT High-COOH parti- ...
15
Nrf2 null enhances UVB-induced skin inflammation and extracellular matrix damages
... and/or inflammation [17,18], and we observed that both of Nrf2 WT and KO mice exhibited increased p53 expression in response to UVB exposure, although the p53 expression was higher in KO ...various skin ...
7
Regulation of cytokines by small RNAs during skin inflammation
... atic skin has been carried out by Sonkoly and co-workers ...psoriasis skin, whereas miR-125b was down- regulated ...lesional skin rather than direct contributors to psoriasis ...in ...
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Pathogenic role for skin macrophages in a mouse model of keratinocyte induced psoriasis like skin inflammation
... 2R). Skin areas of the neck and lower back in mice that were not injected with clo- dronate liposomes showed signs of the phenotype, although these seemed to be milder than in mice injected with control liposomes ...
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Chronic, not acute, skin specific inflammation promotes thrombosis in psoriasis murine models
... to skin inflammation have recently been investigated pre-clinically using acute (5 days) topical application of Aldara (5 % imiquimod; a TLR7/8 agonist) ...lesional skin of both models, including ...
10
Mycobacterium bovis BCG Vaccination Induces Divergent Proinflammatory or Regulatory T Cell Responses in Adults
... local skin reactivity 8 weeks after BCG vaccination, but not with TST con- version after vaccination ...high skin reactivity, suggesting that a simple phenotype like vaccine-in- duced skin ...
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Soothing and anti-itch effect of quercetin phytosome in human subjects: a single-blind study
... against skin inflammation induced by different insults, including UV radiation, histamine prick test, skin barrier disruption induced by contact with SLS or GA ...the skin barrier functions, ...
8
Controlling Systemic Inflammation by Careful Formulation of Topical Skin Care Products: Our Bodies Didn’t Evolve With All the Current Chemicals in Skin Care Products
... of skin inflammation inducing systemic inflammation (Ye et al, 2019), a cormorbidity has been described for AD with rheumatoid arthritis (RA) and irritable bowel disease (IBD), and the authors ...
32
The Pro-inflammatory Role of TGFβ1: A Paradox?
... develop skin in- flammatory phenotypes during their lifespan, and visible skin inflammation manifests at around 2-months of ...in skin lesions ...lesional skin, and high-serum IgE ...
8
Anti-inflammatory effect of fullerene C60 in a mice model of atopic dermatitis
... 36. Hussain Z, Katas H, Mohd Amin MC, Kumolosasi E, Sahudin S. Downregu- lation of immunological mediators in 2,4-dinitrofluorobenzene-induced atopic dermatitis-like skin lesions by hydrocortisone-loaded chitosan ...
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