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skin tumor

Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors

Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors

... in skin tumors in vivo. We have recently found that in skin carcinomas EGF-R plays an important role in triggering the angio- genic switch necessary for skin tumor growth ...in skin ...

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Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor.

Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor.

... The MAPK Pathway Is Vital for Skin Hyperplasia Induced by Pten Loss. Loss of Pten in keratinocytes has been reported to induce phosphorylation of Erk, the canonical target of Ras–MAPK signaling (6, 8). We ...

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Case Report CD31 is a surrogate marker for blastic plasmacytoid dendritic cell neoplasm: a case of a hematologic skin tumor immunohistochemically false negative for CD45

Case Report CD31 is a surrogate marker for blastic plasmacytoid dendritic cell neoplasm: a case of a hematologic skin tumor immunohistochemically false negative for CD45

... the skin in the adult constitute one of the diagnostic challenges for histopathologists, because their differential diagnosis covers a broad spectrum of tumors of epithelial as well as non-epithelial ori- ...the ...

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Inhibition of skin carcinogenesis by suppression of NF-κB dependent ITGAV and TIMP-1 expression in IL-32γ overexpressed condition

Inhibition of skin carcinogenesis by suppression of NF-κB dependent ITGAV and TIMP-1 expression in IL-32γ overexpressed condition

... Human skin tumor tissue microarrays were purchased from US Biomax (SK801b; Rockville, MD, ...mouse tumor tissue sec- tions were blocked for 60 min with 2% normal horse or goat serum diluted in ...

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17b-Estradiol is Abundant in Skin and Regulates the Hair Follicle Cycle and Mirex Tumor Promotion

17b-Estradiol is Abundant in Skin and Regulates the Hair Follicle Cycle and Mirex Tumor Promotion

... not exhibit sexual dimorphism (86). The hair follicle bulge stem cell may be the target cell for chemical carcinogenesis (33). As mentioned earlier, the dermal papilla of the telogen hair follicle expresses the estrogen ...

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Redox Factor 1 Mediates Inflammatory Response during Tumor Promotion in Skin Epidermal JB6 Cells

Redox Factor 1 Mediates Inflammatory Response during Tumor Promotion in Skin Epidermal JB6 Cells

... stage skin tumor promotion by comparing the expression of the NF-B transactivation subunit p65 in both promotion-sensitive (P+) and promotion-resistant (P−) ...stage tumor promotion in skin ...

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A Literature Review of Some Deseases Can Cured With  Tea Component

A Literature Review of Some Deseases Can Cured With Tea Component

... The polycomb group (PcG) proteins are epigenetic regulators of gene expression that enhance cell survival. The increased expression of key PcG proteins in immortalized keratinocytes and skin cancer cell lines. ...

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Human skin carcinoma arising from kidney transplant–derived tumor cells

Human skin carcinoma arising from kidney transplant–derived tumor cells

... human skin cancer after allogeneic transplantation; however, the donor contribution to the malignant epithelium has not been ...invasive skin squamous cell carcinoma (SCC), which is associated with ...

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Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine KrasG12D induced skin carcinogenesis in vivo

Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine KrasG12D induced skin carcinogenesis in vivo

... focal skin hyperplasia at 10–15 days of age and as early as 4 weeks of age developed massive skin papillomas ...the skin papilloma development was ...accelerated skin tumor formation ...

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Deletion of C/EBPß in Oncogenic Ras-Driven Skin Tumors is a Synthetic Lethal Event Promoting p53-Dependent Apoptosis, a Type I Interferon Response, and Tumor Regression.

Deletion of C/EBPß in Oncogenic Ras-Driven Skin Tumors is a Synthetic Lethal Event Promoting p53-Dependent Apoptosis, a Type I Interferon Response, and Tumor Regression.

... driven skin tumorigenesis. Murine skin tumors initiated with the chemical carcinogen DMBA and promoted with TPA have a reported 95-100% mutation rate in Ha-Ras causing a A to T transversion at the 182 nd ...

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Utilizing Free Skin Grafts in the Repair of Surgical Wounds

Utilizing Free Skin Grafts in the Repair of Surgical Wounds

... the tumor extending over his nasal tip, right nasal side- wall, right alar nose and nostril ...The tumor was ex- cised together with the underlying cartilage (Figure ...

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PET/MRI for Preoperative Planning in Patients with  Soft Tissue Sarcoma: A Technical Report of Two Patients

PET/MRI for Preoperative Planning in Patients with Soft Tissue Sarcoma: A Technical Report of Two Patients

... relevant tumor volumes and evaluated the relations to skeletal periosteum and nerve ...of tumor tissue into important adjacent anatomical structures can be ...

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Glyco-Dendrimers as Intradermal Anti-Tumor Vaccine Targeting Multiple Skin DC Subsets

Glyco-Dendrimers as Intradermal Anti-Tumor Vaccine Targeting Multiple Skin DC Subsets

... human skin explants (Bergman Clinics, Bilthoven, The Nether- lands) obtained within 24 hours following abdominal resection of healthy donors with informed ...

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Case Report Dermatofibrosarcoma protuberans in breast: a case report and review of literature

Case Report Dermatofibrosarcoma protuberans in breast: a case report and review of literature

... painless skin nodules, and grows slowly over a span of several years to several ...superficial skin and subcutaneous tissue of the trunk (50%-60% of all DFSP), followed by that in the limbs, head and ...

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Therapeutic Effects of Holmium 166 Chitosan Complex in Rat Brain Tumor Model

Therapeutic Effects of Holmium 166 Chitosan Complex in Rat Brain Tumor Model

... Brachytherapy, which is performed to enhance the treatment effects and reduce the side effects associated with radiotherapy, is a treatment method that uses a toxic dosage of radiation to the specific tumor while ...

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Anal phyllodes tumor in a male patient: a unique case presentation and literature review

Anal phyllodes tumor in a male patient: a unique case presentation and literature review

... these tumor cells clearly (Figure 4i) [14]. Still another such tumor is fibroadenoma phyllodes, which is a histological feature similar to that of low-grade phyllodes tumor ...phyllodes tumor ...

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Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome

Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome

... irradiation, tumor lesions were treated with antennapedia control peptide or with p50 decoy peptide (Imgenex, San Diego, CA; intralesional; 25 μg/tumor in 50 μl ...The tumor number and size were ...

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Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma

Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma

... Three months post-surgery, imaging by CT scan revealed a large local recurrence in the residual liver segment 4, as well as peritoneal implants, retroperitoneal lymph nodes and surrenal and lung metastases. A few days ...

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Tumor heterogeneity in neoplasms of breast, colon, and skin

Tumor heterogeneity in neoplasms of breast, colon, and skin

... whole tumor genomic profiles ...primary tumor cell subpopulation P1, but doesn’t show a close relationship with the rest of the subpopulations in the primary tumors, implying that only this subpopulation ...

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Feasibility of Sorafenib Combined with Local Radiotherapy in Advanced Hepatocellular Carcinoma

Feasibility of Sorafenib Combined with Local Radiotherapy in Advanced Hepatocellular Carcinoma

... of tumor thrombosis or vessel invasion; and 3) patients with metastasis but the tumor burden could be covered by radiation or main tumor burden was inside or near the ...

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