SLE, systemic lupus erythematosus
Systemic Lupus Erythematosus (SLE)
... of lupus in the body brings forth the question of what the etiology ...(CDC), lupus primarily occurs in women approximately four to twelve women for every man, and more frequently occurring in the ...
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Successful use of Ustekinumab in a Patient with Psoriasis, Psoriatic Arthritis and Systemic Lupus Erythematosus: A Case report and Review of literature
... of systemic and cutaneous lupus included “SLE”, “systemic lupus erythematosus”, “discoid lupus”, “acute cutaneous lupus erythematosus”, “subacute cutaneous ...
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Systemic lupus erythematosus and pulmonary arterial hypertension: links, risks, and management strategies
... pressure; SLE-PAH, SLE-associated PAH; SLE, systemic lupus erythematosus; PAH, pulmonary arterial hypertension; PDE5, phosphodi-esterase type 5 inhibitors; RVSP, right ...
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Neuropsychological patterns in systemic lupus erythematosus patients with depression
... All statistical analyses were conducted with the SAS statistical analysis package (version 9.1; SAS Institute Inc., Cary, NC, USA). Data are presented as means ± SDs for continuous var- iables and as numbers of subjects ...
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Serum Vascular Endothelial Growth Factor (VEGF) as a Biomarker for Disease Activity in Lupus Nephritis
... Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder with a broad spectrum of clinical presentations ...(1). Lupus nephritis (LN) is a common manifestation of ...
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Population and family studies of three disease related polymorphic genes in systemic lupus erythematosus
... multiplex SLE families, 41 unrelated lupus patients, and 88 unrelated healthy ...and SLE in these ...sporadic SLE, the study fails to support this association in familial SLE ...in ...
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Increased Tim-3 expression on peripheral T lymphocyte subsets and association with higher disease activity in systemic lupus erythematosus
... While Fas/FasL is the main pathway for cell death in SLE pathogenesis, signaling by Tim-3/galectin-9 also con- tributes to lymphocyte apoptosis. Tim-3 is a powerful im- munosuppressive molecule involved in immune ...
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Chicken or the Egg: Anorexia Nervosa and Systemic Lupus Erythematosus in Children and Adolescents
... of SLE and had ...of SLE (Table ...the lupus anticoagulant was negative in all 6 ...a Systemic Lupus Disease Activity Index score of $ ...
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Cathepsin G and Its Role in Inflammation and Autoimmune Diseases
... in systemic lupus erythematosus (SLE), and the CTSG antibodies in the sera of active SLE patients were significantly increased than inactive patients and healthy controls, and rapidly ...
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New onset non infectious pulmonary manifestations among patients with systemic lupus erythematosus in Sweden
... The SLE cases and general population comparators were predominantly adults and approximately 85% were fe- male (Table ...prevalent SLE cases starting follow up when prescription data were available (mid ...
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A circulating inhibitor of fluid phase amplification C3 convertase formation in systemic lupus erythematosus
... amplification convertase, C3b,Bb, in 37 serum specimens from 24 patients with systemic lupus erythematosus (SLE). C3b,Bb formation was measured by the concentration of Ba, released when C3b,B ...
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IL-22 production of effector CD4+ T-cells is altered in SLE patients
... Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown ...of SLE. Although the pre- cise pathogenesis of SLE has not been fully elucidated, T-cell-dependent ...
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Anti C1q antibodies antedate patent active glomerulonephritis in patients with systemic lupus erythematosus
... A major pathogenic hypothesis is that SLE involves defective renal clearance of immune complexes. Among immunological parameters, consumption of the early components of the clas- sical complement pathway, such as ...
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Concerns of patients with systemic lupus erythematosus and adherence to therapy – a qualitative study
... female Specialist Registrar in Rheumatology with a special interest in SLE, but with no previous relationship with the participants. Interviews, with an approximate duration of 30–40 minutes, were conducted in ...
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ASSOCIATION LUPUS AND TUBEROUS SCLEROSIS: IS IT POSSIBLE? THE INVOLVEMENT OF MTOR PATHEWAY
... Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of autoantibodies against nuclear antigens, and a strong female ...
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Spectrum of paediatric rheumatic diseases in Nigeria
... of systemic onset JIA. Others were 18 (24.6%) cases of juvenile systemic lupus erythematosus (JSLE), 3 ...juvenile systemic sclerosis, 2 ...polymyositis-systemic lupus ...
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Systemic lupus erythematosus and thrombosis
... in SLE pathogen- esis ...of SLE showed that Atorvastatin reduces the level of autoanti- bodies and improves proteinuria and renal histology, how- ever, there is still no general consensus for its extensive ...
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Biomarkers of Systemic Lupus Erythematosus and Systemic Sclerosis Diseases Activity in a Sample of Egyptian Patients :Soluble Intercellular Adhesion Molecule-1 and Soluble Interleukin-2 Receptor, Case Control Study
... higher concentrations of sIL-2R in the cell culture in the active phase of SLE in their study. They explained this by that cells from patients with active SLE have marked response to stimulation by TLR3 and ...
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Five year retrospective study of mortality in systemic inflammatory rheumatologic disorders
... are systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), ankylosing spondylitis, autoimmune myositis, systemic sclerosis and related disorders and various types of ...
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Tumor necrosis factor α release in peripheral blood mononuclear cells of cutaneous lupus and dermatomyositis patients
... Several studies have examined TNFa in skin lesions and serum of patients with CLE and DM. TNFa is increased in lesional skin of patients with DLE and SCLE compared to controls [12-15]. DM lesional skin expresses TNFa, ...
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