small heat shock protein
Differential Subcellular Localization of Members of the Toxoplasma gondii Small Heat Shock Protein Family
... The results of this study describe the identification and characterization of the Toxoplasma gondii ␣ -crys- tallin/small heat shock protein (sHsp) family. By database (www.toxodb.org) search, ...
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Small Heat Shock Protein aa-crystallin Prevents Photoreceptor Degeneration in Experimental Autoimmune Uveitis
... Intravenous administration of aA selectively protects retina in aA2/2 mice against autoimmune induced inflammation and cell death in EAU (Fig. 1). This remarkable protection of the retinal phenotype in aA2/2 EAU mice ...
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The small heat shock protein aA-crystallin negatively regulates pancreatic tumorigenesis
... the small heat-shock protein family (sHSPs) with multiple ...functions. Small HSPs act as molecular chaperones, and participate in signaling transduction, cell proliferation, cell ...
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Use of the Immunodominant 18-Kilodalton Small Heat Shock Protein as a Serological Marker for Exposure to Mycobacterium ulcerans
... While it is well established that proximity to wetlands is a risk factor for contracting Buruli ulcer, it is not clear what proportion of a population living in an area where the etiologic agent, Mycobacterium ulcerans, ...
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Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis
... this longevity phenotype of CL2070. Independent on this basic longevity phenotype of CL2070, the animals show a hormetic stress response allowing the worms to cope properly with the increased ROS challenge caused by ...
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Drosophila small heat shock protein CryAB ensures structural integrity of developing muscles, and proper muscle and heart performance
... IF protein desmin, helps to maintain cytoskeletal integrity in skeletal and cardiac muscle cells (Golenhofen et ...IF protein) orthologs exist in Drosophila (Sparrow and Schöck, 2009), suggesting that other ...
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Maternal loading of a small heat shock protein increases embryo thermal tolerance in Drosophila melanogaster
... of heat shock protein expression on whole-organism thermal tolerance, with one study showing that targeted gene knockdown of Hsp22 and Hsp23 in adult ...the heat shock response (Hofmann ...
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Small heat shock protein 20 (Hsp20) facilitates nuclear import of protein kinase D 1 (PKD1) during cardiac hypertrophy
... Cardiac myocytes respond to pathological stress via activation of the fetal gene programme (reviewed in [1]). Essential to this process, is the activation of cardiac protein kinase D (PKD). PKD1 is a ubiquitously ...
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The role of small heat-shock protein αB-crystalline (HspB5) in COPD pathogenesis
... Plasma levels of MMP-9 were measured only in 26 COPD patients with GOLD III (GOLD, 2008) using RayBiotech (Norcross, GA) Human MMP-9 ELISA kit (Cat # ELH MMP9-001) according to the manufacturer’s instructions. In brief, ...
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Neuroprotection by heat shock protein 27 in sensory and motor neurons
... the small heat shock protein 27 (Hsp27) to prevent apoptotic neuronal death has been examined in primary sensory and motor ...very small proportion (-5% ) o f injured ...
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The Gordian knot of small heat shock proteins and tissue transglutaminae
... The small heat shock proteins (sHsps) have a little shorter historical background; as a matter of fact our lab was one of the laboratories where their stories all began some 30 years ...of ...
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Heat shock protein and heat shock factor 1 expression and localization in vaccinia virus infected human monocyte derived macrophages
... a heat shock in human blood adherent monocytes was also found [32], therefore the heat shock response seems to be similar in this aspect to the vaccinia virus ...stress-inducible ...
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The BAG3-dependent and -independent roles of cardiac small heat shock proteins
... and protein structure studies reveal that this muta- tion results in an irregular structure that stabilizes a closed-groove dimer, forms large oligomers, and is prone to aggregation (11, ...
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The Heat Shock Protein Story—From Taking mTORC1,2 and Heat Shock Protein Inhibitors as Therapeutic Measures for Treating Cancers to Development of Cancer Vaccines
... Heat shock protein 90 (HSP90), together with its co-chaperones, can help over 200 nascent polypeptides to fold correctly, eventually leading to synthesis of the proper proteins for constitutive cell ...
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PRION PROTEIN: PHOTO-OXIDATION, AMYLOIDOGENESIS AND INTERACTION WITH SMALL HEAT SHOCK PROTEINS
... prion protein and to investigate the effect of UV-light and metal ions on the ...copper-prion protein interaction in terms of its conformation and its aggregation ...propensity. Small heat ...
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Anti-Vpr Activities of Heat Shock Protein 27
... another heat-shock protein, HSP70, has activities similar to those described here for HSP27: it suppresses Vpr-induced cell cycle arrest and apoptosis, and inhibits HIV replication ...the ...
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Nuclear p26, a small heat shock/α crystallin protein, and its relationship to stress resistance in Artemia franciscana embryos
... with heat shock or anoxia, and those from homogenates incubated at acid pH contained p26 distributed unevenly throughout ...contain small amounts of p26 and prompting us to determine the exact ...
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Characterization of Heat Shock Protein-Specific T Cells in Atherosclerosis
... The cytokine profiles of the peripheral blood T-cell lines and the PHA-expanded artery lines showed a trend toward a Th2 profile particularly in the CD8 cells with a higher percentage positive for IL-4 than for IFN- ␥ ...
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Original Article Differential expression of heat shock protein 90 isoforms in small cell lung cancer
... In conclusion, this study is the first to investi- gate the differential expression of 4 types of HSP90 isoforms and the correlation of their expression levels with various clinicopathologi- cal factors and patient ...
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Response of circulating heat shock protein 70 and anti heat shock protein 70 antibodies to catheter ablation of atrial fibrillation
... Heat shock proteins (HSPs) are characterized as molecu- lar chaperones and have important functions in the pres- ervation and protection of cells and organs from stress and ...and small HSP families ...
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