THE SMALL HEAT SHOCK PROTEINS
The molecular evolution of the small heat-shock proteins in plants.
... Additions of other eukaryotic small heat-shock proteins (from yeast and humans) to the data matrix make alignment more difficult and, in addition, do not resolve the re[r] ...
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Structure, function and evolution of small heat shock proteins
... lin-related small heat shock proteins (sHsps), the databases available from the public International Human Genome Sequencing Consortium (IHGSC) and the private Celera human genome project were ...
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The Gordian knot of small heat shock proteins and tissue transglutaminae
... The small heat shock proteins (sHsps) have a little shorter historical background; as a matter of fact our lab was one of the laboratories where their stories all began some 30 years ...of ...
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Small heat shock proteins and apolipoprotein E in Alzheimer's disease.
... Aβ-associated proteins, that may affect the biological function of Aβ (119), amongst which are the small heat shock proteins ...(sHsps). Small Hsps represent a family of ...
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The BAG3-dependent and -independent roles of cardiac small heat shock proteins
... 45. Depre C, et al. H11 kinase is a novel mediator of myocardial hypertrophy in vivo. Circ Res. 2002;91(11):1007–1014. 46. Verschuure P, Tatard C, Boelens WC, Grongnet JF, David JC. Expression of small heat ...
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Small heat-shock proteins: important players in regulating cellular proteostasis
... chaperone proteins, which are present both intra- and ...ubiquitous small heat-shock proteins (sHsps) are a family of intracellular molecular chaperones that interact with partially ...
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The growing world of small heat shock proteins: from structure to functions
... Small Heat Shock Proteins (sHSPs) belong to the superfamily of HSPs and are expressed in all three domains (viruses, archaea, bacteria and eukaryota) (Bult et ...a small molecular ...
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PRION PROTEIN: PHOTO-OXIDATION, AMYLOIDOGENESIS AND INTERACTION WITH SMALL HEAT SHOCK PROTEINS
... propensity. Small heat shock proteins are known to be present in plaques of neurodegenerative ...of small heat shock proteins in prion ...
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Translation of Some Maize Small Heat Shock Proteins Is Initiated From Internal In-Frame AUGs
... A B S T R A C T Etiolated maize radicles (inbred Oh43) subjected to a brief heat shock synthesize a family of small heat shock proteins ( . 18 kD) that is composed of at least 12 ...
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Replica Exchange Molecular Dynamics Simulations Provide Insight into Substrate Recognition by Small Heat Shock Proteins
... The small heat shock proteins (sHSPs) are a virtually ubiquitous and diverse group of molecular chaperones that can bind and protect unfolding proteins from irreversible ...
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Small heat shock proteins: Role in cellular functions and pathology
... inhibits heat shock factor-1 (HSF-1) expression and the binding of HSF-1 to the heat shock element [395] ...general heat shock response inhibitors, developing speci fic functional ...
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Genome wide analysis of small heat shock proteins involved in yeast ageing
... Chapter 5. An unbiased approach to identify genetic interactions of HSP12/HSP26 5.3.5 Synthetic genetic array analysis of HSP26 with glucose depletion. One of the benefits of SGA analysis is that it can give insights ...
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Chemical Approaches for ‘Undruggable’ Targets: The Discovery of Ligands for Small Heat Shock Proteins.
... due"to"small"molecule"binding."C:"The"mixed;solvent"molecular"dynamics"method"may"be"used"for"both"binding"site" ...
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Small Heat Shock Proteins Are Novel Common Determinants of Alcohol and Nicotine Sensitivity in Caenorhabditis elegans
... the heat shock transcription factor, HSF-1, and its downstream effectors played as common genetic modulators of sensitivity to addictive ...a small heat shock protein (HSP) homolog of ...
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The preferential heterodimerization of human small heat shock proteins HSPB1 and HSPB6 is dictated by the N-terminal domain
... a small increase in activity over the individual sHSPs was observed, while with insulin the activity of the heterooligomer was significantly greater than the parent sHSPs ...relevant proteins, as well as ...
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Small heat shock proteins are induced during multiple sclerosis lesion development in white but not grey matter
... of small HSP in reactive astrocytes following acute neurotrauma [39–42] and during chronic neurodegenerative disease [43, ...to small HSP ex- pression in astrocytes being a secondary response to damage, and ...
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Plant heat-shock proteins: A mini review
... Stress; Heat stress; Heat tolerance Abstract Plants as sessile organisms are exposed to persistently changing stress ...of proteins called heat-shock proteins (Hsps) or ...
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Heat Shock Proteins: Functions And Response Against Heat Stress In Plants
... and small heat shock proteins, confirming proteomic ...of heat shock factor 21 suppressed that of Zat12, a water-responsive zinc finger protein required for expression of APX1, ...
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The interaction of small heat shock molecular chaperone proteins with a-synuclein
... cellular proteins, including sHsps, potentially depleting the cell of these essential components (2) Initiation of the heat shock response: An accumulation of toxic α-syn species within the cell ...
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Heat-shock proteins in neuroinflammation
... Extracellular small molecular weight HSPs have also been associated with different pathological states, as HSPB1 has been detected in the serum of patients with several types of cancer, such as breast cancer ( ...
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