SMMC-7721
Antitumor effects of a new compound TW9183 on human A549 lung cancer and SMMC 7721 hepatoma cell lines
... and SMMC-7721 cell lines were caused by cellular senescence, ...on SMMC-7721 cell lines was better than on A549 cell lines, this result was consistent with the animal experimental results ...
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<p>Chrysin inhibits sphere formation in SMMC-7721 cells via modulation of SHP-1/STAT3 signaling pathway</p>
... Chrysin (5, 7-dihydroxy fl avone) is a natural fl avone widely found propolis and honey. Chrysin is well docu- mented to possess multiple biological activities, such as antioxidant, anti-in fl ammatory, especially anti- ...
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Dicranostigma leptopodum (maxim) fedde induced apoptosis in SMMC 7721 human hepatoma cells and inhibited tumor growth in mice
... on SMMC-7721 Human Hepatoma Ce- lls in an apoptosis-inducing manner, through MTT assaying, Trypan blue exclusion assaying and cytometric analysis of cell cycle distribu- ...
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Ethylacetate extract from <em>Tetrastigma hemsleyanum</em> inhibits proliferation and induces apoptosis in HepG2 and SMMC-7721 cells
... EET inhibits the proliferation and colony formation of HepG2 and SMMC-7721 cells and regulates apoptosis via the Caspase family and Bcl-2 gene family signaling pathways. EET exhibits a significant ...
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Synergistic Effect of Functionalized Nickel Nanoparticles and Quercetin on Inhibition of the SMMC 7721 Cells Proliferation
... On the basis of these observations, the cytotoxicity sup- pression effect of quercetin on SMMC-7721 cells in the absence and presence of Ni nanoparticles has been further explored by MTT assay. As shown in ...
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Pure paclitaxel nanoparticles: preparation, characterization, and antitumor effect for human liver cancer SMMC-7721 cells
... China). SMMC-7721 cell lines, Tris-buffered saline Tween solution (TBST), PBS, RPMI 1640 medium, Annexin V-fluores- cein isothiocyanate (FITC), MTT, propidium iodide (PI), fetal bovine serum (FBS), and ...
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Intestinal probiotics E. coli Nissle 1917 as a targeted vehicle for delivery of p53 and Tum-5 to solid tumors for cancer therapy
... of SMMC-7721 tumor-bearing BALB/c nude ...hepatoma SMMC-7721 cells, and the antitumor effect of EcN (Tum 5-p53) expressing the Tum 5-p53 fusion protein was significantly better than those of ...
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Anti-tumor effects of brucine immuno-nanoparticles on hepatocellular carcinoma
... Effects of BIN on cell adhesion of liver cancer cells Serum-free 1640 was used to dilute Matrigel (100 µ g/mL), and 25 µ L of the solution was then added to each of the 96 wells in the plate and left to dry in a ...
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Lrig1 is a positive prognostic marker in hepatocellular carcinoma
... To elucidate the biological significance of Lrig1 in HCC, we examined the expression of Lrig1 in primary paired HCC tissue samples. While normal liver specimens showed posi- tive protein expression, primary liver cancer ...
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Methylation mediated Gadd45β enhanced the chemosensitivity of hepatocellular carcinoma by inhibiting the stemness of liver cancer cells
... with 5‑azacytidine increased sensitivity of liver cancer cells to cisplatin, and decreased the stemness of HCC cell lines 5-azacytidine (5-AZA) is the DNA methyltransferase (DNMT) inhibitor, thus we hypothesized that ...
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MALAT1 functions as a competing endogenous RNA to regulate SMAD5 expression by acting as a sponge for miR-142-3p in hepatocellular carcinoma
... The role of MALAT1 in cell migration and invasion of hepatocellular carcinoma cells was further explored. As shown in Fig. 5a–c, the ectopic expression of SMAD5 significantly increased migration and invasion viabil- ity ...
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Oxidative phosphorylation activation is an important characteristic of DOX resistance in hepatocellular carcinoma cells
... in SMMC- 7721/DOX cells ...in SMMC-7721 cells ...in SMMC-7721/DOX cells ...in SMMC-7721 cells ...in SMMC-7721 cells ...in SMMC-7721/DOX ...
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Hypoxia-inducible gene 2 promotes the immune escape of hepatocellular carcinoma from nature killer cells through the interleukin-10-STAT3 signaling pathway
... and SMMC-7721 ...and SMMC-7721 cells transfected with siR-HIG2 were sig- nificantly lower than that in the cells transfected with siR-NC (P < ...and SMMC-7721 cells trans- ...
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Biscarbamate cross-linked low molecular weight Polyethylenimine polycation as an efficient intra-cellular delivery cargo for cancer therapy
... PEI 25 K was used as a positive transfection agent in vivo, but cytotoxicity has largely prohibited its clinical use in vivo. Combined the low toxicity and high transfection efficiency of PEI derivatives, biscarbamate ...
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Long noncoding RNA miR503HG, a prognostic indicator, inhibits tumor metastasis by regulating the HNRNPA2B1/NF-κB pathway in hepatocellular carcinoma
... that SMMC-7721 and Huh7 cells overexpressing miR503HG had dramatically reduced migratory and invasive capacity compared with the vector control (Figure ...Furthermore, SMMC-7721 cells infected ...
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miR-15b-5p induces endoplasmic reticulum stress and apoptosis in human hepatocellular carcinoma, both in vitro and in vivo , by suppressing Rab1A
... treated SMMC-7721 ...in SMMC-7721 or Hep3B cells reversed the miR-15b-5p-inhibitor-induced growth enhancement and resulted in apoptosis inhibition (Figure ...
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Anti-insulin-like growth factor-IIP3 DNAzymes inhibit cell proliferation and induce caspase-dependent apoptosis in human hepatocarcinoma cell lines
... ie, SMMC-7721, HepG2, and Huh7, were analyzed after DRz-mediated IGF-IIP3 ...in SMMC-7721 cells after the first 24 hours and dropped to ∼ 15% over the next 48 ...the SMMC-7721 ...
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TPP-related mitochondrial targeting copper (II) complex induces p53-dependent apoptosis in hepatoma cells through ROS-mediated activation of Drp1
... In many cases, the cytotoxicity of copper complexes originates from the generation of ROS driven by the metal. Meanwhile, ROS plays a significant role in apop- tosis activation by many chemotherapeutical drugs and ...
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Tensin4 is up-regulated by EGF-induced ERK1/2 activity and promotes cell proliferation and migration in hepatocellular carcinoma
... in SMMC-7721, we demonstrated that Tensin4 was required for cell proliferation and EGF-induced cell migration in HCC cells, suggesting an oncogenic role of Tensin4 in HCC ...affected SMMC-7721 ...
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Original Article Down-expression of homeobox A9promotes cancer cell invasion in human hepatocellular carcinomas
... shHOXA9, SMMC-7721-HOXA9 and their corre- Figure ...HHL-5-shHOXA9, SMMC-7721-HOXA9 or their control ...(B), SMMC-7721-HOXA9 (C) ortheir control ...
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