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Smooth muscle contraction

Epithelium generated neuropeptide Y induces smooth muscle contraction to promote airway hyperresponsiveness

Epithelium generated neuropeptide Y induces smooth muscle contraction to promote airway hyperresponsiveness

... airway smooth muscle ...underlying smooth muscle to induce AHR and suggest that therapies targeting epithelial induction of this phenotype may prove useful in treatment of noneosinophilic ...

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The effects of interleukin-8 on airway smooth muscle contraction in cystic fibrosis

The effects of interleukin-8 on airway smooth muscle contraction in cystic fibrosis

... Many inflammatory cytokines are produced in the air- ways in CF patients [13]. Several studies have docu- mented increased levels of interleukin-8 (IL-8; CXCL8) in bronchoalveolar lavage fluid and sputum and increased ...

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Yu, Qingfeng
  

(2018):


	Inhibition of human prostate smooth muscle contraction by the LIM kinase inhibitors, SR7826 and LIMKi3.


Dissertation, LMU München: Medizinische Fakultät

Yu, Qingfeng (2018): Inhibition of human prostate smooth muscle contraction by the LIM kinase inhibitors, SR7826 and LIMKi3. Dissertation, LMU München: Medizinische Fakultät

... Herbal drugs are made of seeds, pollen, roots, bark, or fruits. Up to date, a growing number of plant extracts, such as izalpinin and phellodendron amurense have been reported to show effects on reducing smooth ...

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Assessment of Myogenic Power Expenditure Due to Arterial Wall Smooth Muscle  Contraction Based upon the Fractal Nature of Vascular Trees

Assessment of Myogenic Power Expenditure Due to Arterial Wall Smooth Muscle Contraction Based upon the Fractal Nature of Vascular Trees

... vascular smooth muscle contraction (VSMC) and 2) to assess the total power expenditure in the entire systemic arterial tree by utilizing the fractal nature of the branching ...

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IQGAP1 dependent scaffold suppresses RhoA and inhibits airway smooth muscle contraction

IQGAP1 dependent scaffold suppresses RhoA and inhibits airway smooth muscle contraction

... airway smooth muscle ...airway smooth muscle contractility, was activated in airway smooth muscle lysates from Iqgap1 –/– ...airway smooth muscle cells increased ...

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Nelumbo nucifera leaves extracts inhibit mouse airway smooth muscle contraction

Nelumbo nucifera leaves extracts inhibit mouse airway smooth muscle contraction

... the contraction of ASM was hard to recover after rinsing, which indicated that the crude extract might have a high affinity and hard to be totally washed ...

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... The present study demonstrates that the aqueous ethanolic leaf extract of M. pruriens induced uterine smooth muscle contraction. This contractile effect was concentration -dependent, and was found to ...

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Involvement of RhoA-mediated Ca2+ sensitization in antigen-induced bronchial smooth muscle hyperresponsiveness in mice

Involvement of RhoA-mediated Ca2+ sensitization in antigen-induced bronchial smooth muscle hyperresponsiveness in mice

... airway smooth muscle ...airway smooth muscle contraction in the airway ...airway smooth muscle cells associated with the ...

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Contraction of atrial smooth muscle reduces cardiac output in perfused turtle hearts

Contraction of atrial smooth muscle reduces cardiac output in perfused turtle hearts

... atrial smooth muscle contraction may benefit turtles during ...atrial smooth muscle contraction (Bottazzi, 1900, 1906; Fano, 1887; Fano and Fayod, 1888; Meek, ...atrial ...

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Original Article Advanced glycation end products inhibit distal colon contraction in rats via protein kinase C-dependent modulation of intracellular calcium

Original Article Advanced glycation end products inhibit distal colon contraction in rats via protein kinase C-dependent modulation of intracellular calcium

... In recent years, an increasing number of gas- trointestinal (GI) complications such as consti- pation, dysphagia, reflux, and nausea have been seen in diabetic patients. The prevalence of GI dysfunction was found to be ...

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Vascular Smooth Muscle Cell Stiffness and Adhesion to Collagen I Modified by Vasoactive Agonists

Vascular Smooth Muscle Cell Stiffness and Adhesion to Collagen I Modified by Vasoactive Agonists

... The alterations in VSMC adhesion to COL-I and FN [4] following treatment with vasoactive agents (constrictor and dilator) may function as a means of tuning adhesion to cellular force generation. As such, when the VSMC is ...

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FENOTEROL BETA- AGONIST ON CONTRACTION AND RELAXATION OF INTESTINAL SMOOTH MUSCLE OF MALE ALBINO BALB-C MICE

FENOTEROL BETA- AGONIST ON CONTRACTION AND RELAXATION OF INTESTINAL SMOOTH MUSCLE OF MALE ALBINO BALB-C MICE

... Visceral smooth muscle contraction occurs spontaneously, meaning that muscle cell action potentials are generated without input from either the motor or autonomic nervous ...The muscle ...

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Microfluidic chest cavities reveal that transmural pressure controls the rate of lung development

Microfluidic chest cavities reveal that transmural pressure controls the rate of lung development

... (the contraction of smooth muscle) is connected to the morphogenesis of an adjacent tissue (the branching of the ...systemic smooth muscle contraction and synchronized epithelial ...

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Pleiotropic microRNA-21 in pulmonary remodeling: novel insights for molecular mechanism and present advancements

Pleiotropic microRNA-21 in pulmonary remodeling: novel insights for molecular mechanism and present advancements

... controls smooth muscle contraction and relaxation, and thus has a major role in the regulation of cell shape and function ...vascular smooth muscle cell (PVSMC) contractility ...in ...

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Coagulation dependent mechanisms and asthma

Coagulation dependent mechanisms and asthma

... airway smooth muscle contraction and airway hyperresponsiveness may be associated with accumulation of extravascular fibrin, plasma exudates, and inflammatory cells that can lead to airway ...

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Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin

Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin

... events through via activation of the protease activated receptors, it is proposed that F2R is the main receptor responsible for mediating these responses [8]. It had pre- viously been demonstrated that thrombin is ...

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Gene expression analysis in asthma using a targeted multiplex array

Gene expression analysis in asthma using a targeted multiplex array

... Other genes in the 5 most differentially up or down regulated genes that were nominaly significant include: Cyclic ADP Ribose (CD38), Interleukin 13 Receptor Alpha 1 (IL13RA1), Prostaglandin F Receptor (PTGFR), Heat ...

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Increased vascular contractility in hypertension results from impaired endothelial calcium signaling

Increased vascular contractility in hypertension results from impaired endothelial calcium signaling

... evoke contraction of quiescent arteries (Figure S5), suggesting that acetylcholine does not cause the release of endothelium-dependent contractile factors in this ...

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Dismantling the pathophysiology of asthma using imaging

Dismantling the pathophysiology of asthma using imaging

... airway smooth muscle mass and reticular basement membrane thickness [46, 47], and this has been confirmed by CT scans taken before and after treatment, where airway wall thickness was less after treatment ...

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Cyclosporine induced synthesis of endothelin by cultured human endothelial cells

Cyclosporine induced synthesis of endothelin by cultured human endothelial cells

... Endothelin (ET), a peptide synthesized by endothelial cells (EC), causes a decreased renal blood flow and glomerular filtration rate and an increased mean arterial pressure when infused in animals. In tissue culture, ET ...

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