Sodium arsenite
Effect of Sodium Arsenite on the Expression of Antioxidant Genes (SOD2 and CAT) in MCF-7 and Jurkat Cell Lines
... Background: Sodium arsenite (NaAsO2) has potent cytotoxic activity in human cancer cells. Oxidative stress has been suggested as a mechanism for arsenic-induced carcinogenesis. The purpose of the present ...
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Histopathological Changes and Antioxidant Enzymes Status in Oxidative Stress Induction Using Sodium arsenite in Rats
... of sodium arsenite show mononuclear inflammatory cell infiltration around myocardial blood vessels as well as fragmentation and degeneration of muscle fibers with pyknotic nuclei in cardiac ...of ...
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Effect of vitamin E on sperm parameters and DNA integrity in sodium arsenite-treated rats
... Materials and Methods: Adult male rats were divided into 4 groups: control, sodium arsenite (8 mg/kg/day), Vit.E (100 mg/kg/day) and sodium arsenite+Vit.E. Oral treatments were performed till ...
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Cytoskeletal Alterations in Lipopolysaccharide-Induced Bovine Vascular Endothelial Cell Injury and Its Prevention by Sodium Arsenite
... Morphological changes, especially cytoskeletal alterations, in lipopolysaccharide (LPS)-induced vascular endothelial cell injury were studied by using LPS-susceptible bovine aortic endothelial cells (BAEC). BAEC in ...
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Hepatoprotective effect of edible Oyster mushroom Pleurotus cornucopiae against Sodium Arsenite induced hepatotoxicity in rats
... arsenite alone treated rats. Similar changes noticed that oral administration of P.cornucopiae and sodium arsenite together treated rats showed SGPT, SGOT, ALP and bilirubin levels were decreased. ...
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Phytoremedial Effect of Pleurotus cornucopiae (Oyster Mushroom) against Sodium Arsenite Induced Toxicity in Charles Foster Rats
... sodium arsenite pre-treated rats. The results show significant decrease in the serum urea, uric acid and creatinine levels in comparison to the arsenic treated denotes the nephroprotective ef- fect of P. ...
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Effect of Irvingia gabonensis Stem Bark on Liver Function in Sodium Arsenite-Exposed Wistar Rats
... to sodium arsenite alone produced vascular congestion and ulceration, infiltration of inflammatory cells and moderate Kupffer cell ...of sodium arsenite [74, ...
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DUAL ROLE OF ARJUNOLIC ACID AND B12 IN MITIGATING SODIUM ARSENITE INDUCED MALFUNCTION OF FEMALE REPRODUCTIVE ORGANS
... minimize the oxidative stress by sustaining the normal cellular level of MT. In chemical structure of AA have hydroxyl groups (one primary and two secondaries) and have one carboxylic hydrogen atom which may important ...
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Silymarin protects plasma membrane and acrosome integrity in sperm treated with sodium arsenite
... In the present study we tested the adverse effects of sodium arsenite on plasma membrane and acrosome integrity of ram epididymal sperm. We also examined the protective effect of silymarin on these ...
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Effects of chronic exposure to sodium arsenite on hypothalamo-pituitary-testicular activities in adult rats: possible an estrogenic mode of action
... matogenesis is may be due to low level of gonadotrophins i.e. LH and FSH [48]. LH and FSH are required for quanti- tatively normal spermatogenesis in pubertal rats [22,49]. The reduction of LH and FSH and consequent ...
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Sodium arsenite induced histochemical changes in the liver of fish Mystus bleekeri (Day)
... the Sodium arsenite causes different degrees of injuries to the fish ...of Sodium arsenite and or may be due to toxicant imposed stress ...
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Emblica Officinalis Protects Against Sodium Arsenite Induced Hepatotoxicity & Nephrotoxicity In Rats
... with Sodium arsenite for 8 weeks to make arsenic model and upon these arsenic pretreated rats Emblica officinalis was administered for 4 weeks to study the antidote effects of this ...
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Co-exposure of Lead Acetate and Sodium Arsenite Causes Alteration in the Markers of Liver and Kidney Functions in Male Wistar Rats
... Adult male albino rats (weighing 120 - 150 g) were obtained from the animal breeding unit at Department of Biochemistry, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria, and were housed in cages, at room ...
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The protective role of vitamin E on the testicular tissue in rats exposed to sodium arsenite during the prenatal stage till sex maturity: A stereological analysis
... with sodium arsenite indicated an increase in the antioxidant enzymes activity and glutathione (GSH) concentration and decrease in lipid peroxidation ...
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Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC)
... cisplatin, sodium arsenite and hyperthermia with different mechanisms of action might be more beneficial than using a single drug to tar- get a single protein or ...
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In vitro Antioxidant/ Radical Scavenging Activities and Hepatoprotective Roles of Ethanolic Extract of Cassia occidentalis Leaves in Sodium Arsenite-Treated Male Wistar Rats
... Sodium arsenite, BHA (butylated hydroxyanisole), BHT (butylated hydroxytoluene) were purchased from Sigma Chemical Co., St Louis, MO, USA. Kits for ALT, AST, ALP and γGT were purchased from Randox ...
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N-acetylcysteine and meso-2,3 dimercaptosuccinic acid alleviate oxidative stress and hepatic dysfunction induced by sodium arsenite in male rats
... Abstract: Environmental exposure to arsenic represents a serious challenge to humans and other animals. The aim of the present study was to test the protective effect of antioxidant N-acetylcysteine (NAC) either ...
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The effects of sodium arsenite on the testis structure and sex hormones in vasectomised rats
... to sodium arsenite leads to pathological damage in the structure of testes (6) and imbalance of sex hormones ...of arsenite and ...of arsenite toxicity and vasectomy together on pathological ...
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GENOPROTECTIVE EFFECTS OF ETHANOLIC STEM EXTRACTS OF TINOSPORA CORDIFOLIA ON SODIUM ARSENITE INDUCED DNA DAMAGE IN SWISS MICE LYMPHOCYTES BY COMET ASSAY
... Sodium arsenite (Sigma, chemical abstracts service [CAS]: 7784-46-5), ethidium bromide (Sigma, CAS: 1239-45-8), normal melting agarose (Biochem Life Sciences, CAS: 9012-36-5), low melting point agarose ...
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Hepatotoxicity and Genotoxicity of Sodium Arsenite and Cyclophosphamide in Rats: Protective Effects of Aqueous Extract of Adansonia digitata L. Fruit Pulp
... Arsenite is a proven human and animal carcinogen. Exposure to arsenic, especially through the intake of polluted well water, has been associated with lesions of the skin and certain forms of cancers [1]. In ...
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