Sodium current
Patch clamp Study of the Properties of the Sodium Current in Cockroach Single Isolated Adult Aminergic Neurones
... Kinetics of the STX-sensitive inward current The kinetic properties of the inward sodium current inactivation were studied using the time course of sodium current decay during a single p[r] ...
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Deterministic and stochastic dynamics of multi variable neuron models : resonance, filtered fluctuations and sodium current inactivation
... We introduced a modified model of the EIF model referred to as the EIFh model which incorporates the dynamics of fast inactivation of the sodium current, h. The steady-state and dynamics response properties ...
204
Breakdown of accommodation in nerve: a possible role for persistent sodium current
... persistent sodium chan- nels are modeled as discrete ...transient sodium channels. Three discrete persistent and late sodium currents have been identified on the basis of inac- tivation kinetics [11] ...
11
Pharmacological properties of axonal sodium channels in the cockroach Periplaneta americana L II Slowing of sodium current turn off by Condylactis toxin
... In particular, the application of voltage-clamp techniques to isolated cockroach giant axons has resulted in the demonstration of a transient, inward sodium current and a late, outward, [r] ...
10
Predicting Function from Structure Using the Poisson Nernst Planck Equations: Sodium Current in the Gramicidin A Channel
... the sodium current through an ion channel of known structure s gramicidin A (gA) s using an electrostatic model of the ion channel and an electrodiffusion model of ion ...
6
Pumilio binds para mRNA and requires nanos and brat to regulate sodium current in drosophila motoneurons
... in differing neurons or disease states (Song et al., 2004). The known mechanism of action of Pum-dependent transla- tional repression is absolutely dependent on additional cofactors. The most studied example, that of hb ...
12
Development and Function of the Voltage-Gated Sodium Current in Immature Mammalian Cochlear Inner Hair Cells
... Inner hair cells (IHCs) of the mature mammalian cochlea relay sound information transduced by mechano-sensitive channels [1] to the central nervous system with high temporal precision [2] via the coordinated release of ...
10
Concomitant SK current activation and sodium current inhibition cause J wave syndrome
... um current I Na and L-type calcium current I Ca,L ) with the concomitant gain of function of the repolarizing currents (such as transient outward potassium current I to and adenosine triphosphate ...
17
The Revitalization of the Community based Management of Acute Malnutrition Program in Haiti
... fast sodium, persistent sodium, and calcium currents at the spike ...persistent sodium current reproduced the dantrolene effects on spike shape and reduced the calcium influx through membrane ...
58
Effect of neutrophil elastase and its inhibitor EPI-hNE4 on transepithelial sodium transport across normal and cystic fibrosis human nasal epithelial cells
... on sodium current in human nasal epithelial cells and in rat alveolar epithelial cells [15,21], suggesting that in these primary cells, ENaC was fully activated by epithelium-derived serine proteases such ...
9
Mechanisms contributing to the dopamine induction of crawl like bursting in leech motoneurons
... a sodium-influx-dependent timing mechanism capable of setting the crawl rhythm and that multiple DA receptor subtypes are involved in shaping and modulating the phase relationships and membrane properties of ...
9
Sodium channels gone wild: resurgent current from neuronal and muscle channelopathies
... Voltage-dependent sodium channels are the central players in the excitabil- ity of neurons, cardiac muscle, and skeletal ...in sodium channels have been associated with human disease, particularly genetic ...
6
Sudden infant death syndrome due to long QT syndrome: a brief review of the genetic substrate and prevalence
... SIDS cases concealed a phenotype of LQTS. More spe- cifically, the majority of the mutations were detected in the SCN5A gene. These mutations caused either an increased persistent sodium current or ...
6
Leptin modulates electrophysiological characteristics and isoproterenol-induced arrhythmogenesis in atrial myocytes
... larger sodium current, but a smaller ultra-rapid delayed rectifier potassium current, and sodium-calcium exchanger current than the ...late sodium current, inward ...
9
Form of Nerve Impulse and its Features of Propagation along the Nerve Fiber cells in Living Systems
... electric current or field, in which the sodium current is formed due to the action of sodium pump and the bio-energy, meanwhile, where the electric-potential of the membrane is also varied to ...
10
Pharmacological properties of axonal sodium channels in the cockroach Periplaneta americana L I Selective block by synthetic saxitoxin
... From the concentration dependence of sodium, current suppression it is concluded that individual sodium channels are blocked by single molecules of synthetic saxitoxin which bind reversi[r] ...
8
Pulse Galvanostatic Synthesis of Zinc-Sulfur Nanocomposites and Application as a Novel Negative Material of Rechargeable Zinc-Manganese Dioxide Alkaline Batteries
... and sodium thiosulfate were used as the ...and sodium thiosulfate ...pulsed current with 18 Hz frequency and 14 ms pulse time was applied for 2 ...
18
TIME COURSE OF THE SODIUM INFLUX IN SQUID GIANT AXON DURING SINGLE VOLTAGE CLAMP PULSE
... The ratio 'measured extra sodium influx/calculated ionic influx from the inward current record' is close to unity and is independent of the duration of the rectangular pulse of membrane [r] ...
14
The Antibiofilm efficacy of nitric oxide on soft contact lenses
... In the current study, we used sodium nitrite (NaNO2) as a NO donor and investigated the inhibitory effects of NO on soft contact lens-associated biofilms by Staphylococcus aureus and Pse[r] ...
8
Energetics of discrete selectivity bands and mutation-induced transitions in the calcium-sodium ion channels family
... treats sodium and calcium ions explic- itly, it fails to include their counter-ions (chloride), either explicitly or implicitly, in the Poisson continuum treat- ment and BD ...
18