Sodium Valproate
The efficacy of intravenous sodium valproate and phenytoin as the first-line treatment in status epilepticus: a comparison study
... and sodium valproate group were ...and sodium valproate groups, respect- ively (Table ...while sodium valpro- ate was given intravenously at average loading dose of 1000 (SD ...average ...
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ANXIOLYTIC ACTIVITY OF GABAPENTIN, PREGABALIN, SODIUM VALPROATE AND ALPRAZOLAM IN WISTAR ALBINO RATS A COMPARATIVE STUDY
... In both acute and chronic models of open field test, rats treated with alprazolam, sodium valproate, gabapentin showed a significant (p<0.05) decrease in the number of entries and total time spent ...
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COMPARING THE RESPONSE SPEED TO SODIUM VALPROATE IN THE TREATMENT OF MANIC EPISODE OF PATIENTS SUFFERING FROM BIPOLAR I DISORDER WITH PSYCHOTIC SYMPTOMS BY RAPID ORAL LOADING AND SLOW TITRATION METHODS
... of sodium valproate are compared to gradual titration ...group, sodium valproate 20 mg / kg is started from the beginning and has continued to seventh day (loading group), and the other group ...
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Comparative study of efficacy and safety of intravenous sodium valproate with intravenous phenytoin sodium in the treatment of status epilepticus in children
... phenytoin sodium/phenobarbitone, diazepam infusion in sequential ...(IV) sodium valproate is safe and effective in controlling paediatric ...intravenous sodium valproate with ...
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Cinnarizine in refractory migraine prophylaxis: efficacy and tolerability. A comparison with sodium valproate
... number of responders showed that in the CIN group 61.2% subjects were responders, and 63.8% in the SV group. No statistically significant differences between the treatment groups were found for any of the secondary ...
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Influence of Spirulina Fusiformis on the Sodium Valproate Induced Hepatotoxicity and Oxidative Stress.
... (32). Sodium valproate is metabolized by fatty acid β-oxidation and conjugated by glucuronic acid with a minimal contribution by omega oxidation, chronic or high-dose sodium valproate therapy ...
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COMPARING THE EFFICACY OF PHENYTOIN, LEVETIRACETAM AND SODIUM VALPROATE IN PREVENTION OF POST-TRAUMATIC SEIZURES IN BRAIN INJURY
... 26. Xue YJ, Ming LI, Zhang Y, LI GZ. Sodium valproate for prevention of early posttraumatic seizures. Chinese Journal of Traumatology (English Edition). 2010 Oct 1; 13(5):293-6. 27. Bratton SL, Chestnut RM, ...
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Zolpidem Potentiate Anticonvulsant Activity of Phenytoin, Sodium Valproate and Lamotrigine in Wistar Rats
... phenytoin; sodium valproate; lamotrigine in separate group (n=6, in each) and the animals were subjected for MES, MET and PTZ induced seizures in the same way as in the previous ...
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Sodium valproate-induced congenital cardiac abnormalities in mice are associated with the inhibition of histone deacetylase
... The C57/B6 mice used in this study were maintained as a pathogen-free colony at Florida Atlantic University at Boca Raton, FL. Wild-type (WT) littermates were used as con- trols in the present study. This investigation ...
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Preparation of coated valproic acid and sodium valproate sustained-release matrix tablets
... and sodium valproate sustained-release matrix ...acid-sodium valproate matrix tablets prepared with wet granulation technique was evaluated in pH change ...
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ADJUNCT ALLOPURINOL TO SODIUM VALPROATE AND HALOPERIDOL IN TREATMENT OF IN PATIENTS WITH ACUTE BIPOLAR MANIA
... of Sodium Valproate and Allopurinol impacts treatment procedure of patients affected by bipolar I disorder who are experiencing a manic ...received Sodium Valproate and placebo) for 4 weeks ...
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73. In vivo activity and pharmacokinetic analysis of combination of piperine and subtherapeutic dose of sodium valproate in refractory epilepsy
... whereas, sodium valproate is known to increase the plasma concentration of the co-administered drug, like lamotrigine. However, this drug interaction does not limit the coadministration of SVP and ...
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FORMULATION AND EVALUATION OF SODIUM VALPROATE SUSTAINED RELEASED TABLETS
... HPMC.Sodium valproate, chemically propyl pentanoate, is first line drug used for its unique anticonvulsant ...moiety. Sodium valproate works by stabilizing electrical activity in the ...seizures. ...
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PREPARATION AND EVALUATION OF MUCOADHESIVE MICROCAPSULES OF SODIUM VALPROATE
... The gelation and cross linking are due to stacking of the glucoronic acid (G) blocks of alginate chains with the formation of egg-box–like structure. Alginate microcapsules are non toxic, have a protective effect on ...
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Randomized controlled clinical trial comparing the efficacy and tolerability of aripiprazole and sodium valproate in the treatment of Tourette syndrome
... All subjects were evaluated at baseline by routine labo- ratory tests, electrocardiogram (ECG), resting pulse rate and blood pressure while sitting, height and weight measurement, medical history, and physical and neu- ...
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STUDY OF THE EFFECT OF SODIUM VALPROATE ON ENHANCEMENT OF MONOAMINE MEDIATED BEHAVIOURAL RESPONSES AFTER ELECTROCONVULSIVE SHOCK (ECS) ADMINISTRATION IN RATS
... of sodium valproate on enhancement of monoamines mediated behavioural responses following administration of ECS for ten days to ...3) Valproate group- valproate ...+ valproate ...
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Sodium valproate in pregnancy: what are the risks and should we use a shared decision making approach?
... Whilst the new requirements are therefore in line with current recommended best practice, there is also evi- dence suggesting an evidence-practice gap. For example, a recent study in the UK showed that around half the ...
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The effect of sodium valproate on chronic daily headache and its subgroups
... Divalproex sodium (composed of sodium valproate and valproic acid) has been found to be useful for the treatment of ...divalproex sodium, and to a lesser extent, gabapentin, have shown ...
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Musanga cecropioides (Urticaceae) stem-bark mitigates sodium valproate –induced pantoxicity derangement in albino rats
... Sodium valproate (SVPA) is indicated for the management of partial and generalized epilepsy with major limitation of pan‐toxicity. Musanga cecropioides stem‐bark (MCS) is used in ethnomedicine for multiple ...
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Estimating the Optimal Dosage of Sodium Valproate in Idiopathic Generalized Epilepsy with Adaptive Neuro-Fuzzy Inference System
... of sodium valproate in IGE ...of sodium valproate in IGE patients when the age of onset and the frequency of seizures during the epilepsy, prior to the onset of therapeutic intervention, are ...
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