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Spiral Ganglion

Original Article Expression patterns of fibroblast growth factor 8 in the spiral ganglion of rat cochlea

Original Article Expression patterns of fibroblast growth factor 8 in the spiral ganglion of rat cochlea

... Previous studies found that FGF8 binds to FGFR1-4 to exert its functions [8]. In the audi- tory system, FGFR1-3 are present in the epithe- lium of the cochlear duct, whereas FGFR4 is restricted to the mesenchyme ...

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Reduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis

Reduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis

... The neurotrophins are a group of proteins that induce survival, differentiation and neurite outgrowth. Two such neuroprotective agents, neurotrophin-3 (NT-3) and brain-derived neurotrophic factor (BDNF), play a signifi- ...

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P2X receptor signaling inhibits BDNF mediated spiral ganglion neuron development in the neonatal rat cochlea

P2X receptor signaling inhibits BDNF mediated spiral ganglion neuron development in the neonatal rat cochlea

... outer spiral bundles (osb). rf, radial fibers. Spiral ganglion neurite outgrowth is promoted by neurotrophins, particularly BDNF, which is a paracrine factor secreted by the hair ...

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Ouabain Does Not Induce Selective Spiral Ganglion Cell Degeneration in Guinea Pigs

Ouabain Does Not Induce Selective Spiral Ganglion Cell Degeneration in Guinea Pigs

... Copyright © 2018 Timo Schomann et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...

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Sensitivity of spiral ganglion neurons to damage caused by mobile phone electromagnetic radiation will increase in lipopolysaccharide-induced inflammation in vitro model

Sensitivity of spiral ganglion neurons to damage caused by mobile phone electromagnetic radiation will increase in lipopolysaccharide-induced inflammation in vitro model

... Methods: Spiral ganglion neurons (SGN) were obtained from neonatal (1- to 3-day-old) Sprague Dawley® (SD) rats. After the SGN were treated with different concentrations (0, 20, 40, 50, 100, 200, and 400 μ ...

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Type I vs type II spiral ganglion neurons exhibit differential survival and neuritogenesis during cochlear development

Type I vs type II spiral ganglion neurons exhibit differential survival and neuritogenesis during cochlear development

... their postsynaptic targets through competition for limit- ing amounts of trophic support supplied by target tissue [3,43,44]. Studies in the cochlea have shown that neona- tal SGNs rely on connectivity with their ...

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No dramatic age-related loss of hair cells and spiral ganglion neurons in Bcl-2 over-expression mice or Bax null mice

No dramatic age-related loss of hair cells and spiral ganglion neurons in Bcl-2 over-expression mice or Bax null mice

... Functional decline of the nervous system is a cardinal fea- ture of aging, yet the cellular mechanisms underlying this decline are unknown. The current view holds that age- related changes of neuronal connections, rather ...

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The development of the spiral ganglion in the human foetus

The development of the spiral ganglion in the human foetus

... in spiral ganglion neurons in all ...of spiral ganglion development follows that of the stria vas- cularis and organ of Corti, although maturation changes are still observed in the neuronal ...

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Nuclear entry of hyperbranched polylysine nanoparticles into cochlear cells

Nuclear entry of hyperbranched polylysine nanoparticles into cochlear cells

... and placed on the round window membrane. A) Lateral view of reconstructed three-dimensional image of the round window membrane showing the gradient distribution of hPNPs; both condensed homogenous nuclear distribution of ...

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Growth factor eluting cochlear implant electrode: impact on residual auditory function, insertional trauma, and fibrosis

Growth factor eluting cochlear implant electrode: impact on residual auditory function, insertional trauma, and fibrosis

... Cochlear implants (CIs) provide auditory perception to in- dividuals with severe to profound sensorineural hearing loss by electrically stimulating spiral ganglion neurons (SGNs) via an electrode array ...

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Distinct capacity for differentiation to inner ear cell types by progenitor cells of the cochlea and vestibular organs

Distinct capacity for differentiation to inner ear cell types by progenitor cells of the cochlea and vestibular organs

... the spiral ganglion (containing Schwann cells and cell bodies of cochlear ...and spiral ganglion progenitors (described in Figs 5 – ...

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Original Article The transplantation of induced pluripotent stem cells into the cochleae of mature mice

Original Article The transplantation of induced pluripotent stem cells into the cochleae of mature mice

... and spiral ganglion ...and spiral ganglion cells in vitro [11]; however, the distribution, migration, and survival of undifferentiated iPSCs after trans- plantation into the inner ear remains ...

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MPZL2, Encoding the Epithelial Junctional Protein Myelin Protein Zero-like 2, Is Essential for Hearing in Man and Mouse

MPZL2, Encoding the Epithelial Junctional Protein Myelin Protein Zero-like 2, Is Essential for Hearing in Man and Mouse

... In a Dutch consanguineous family with recessively inherited nonsyndromic hearing impairment (HI), homozygosity mapping com- bined with whole-exome sequencing revealed a MPZL2 homozygous truncating variant, c.72del ...

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Animal Model of Sensorineural Hearing Loss Associated with Lassa Virus Infection

Animal Model of Sensorineural Hearing Loss Associated with Lassa Virus Infection

... the spiral limbus, stria vascularis, and spiral gan- glion ...the spiral ganglion, stria vascularis, and also within the scala tympani cell infiltrates in Stat1 ⫺/⫺ mice infected with ...

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Biocompatibility of Liposome Nanocarriers in the Rat Inner Ear After Intratympanic Administration

Biocompatibility of Liposome Nanocarriers in the Rat Inner Ear After Intratympanic Administration

... including spiral ligament, spiral limbus, and stria vascularis were se- lected using freehand selections ...cells, spiral ganglion cells, spiral ligament, and spiral limbus were ...

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Bilateral tympanokeratomas (cholesteatomas) with bilateral otitis media, unilateral otitis interna and acoustic neuritis in a dog

Bilateral tympanokeratomas (cholesteatomas) with bilateral otitis media, unilateral otitis interna and acoustic neuritis in a dog

... the spiral ganglion of the ves- tibulocochlear nerve (cranial nerve VIII) and inflamma- tory infiltrates and haemorrhage were observed within the spiral ganglion and in the surrounding bone ...

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Equiangular Spiral Slot Antenna for C  band Applications

Equiangular Spiral Slot Antenna for C band Applications

... Equiangular Spiral Slot Patch Antenna has been designed and simulated at operating frequency range between 4 GHz to 10 ...equiangular spiral slot on the circular ...of Spiral slot. The results of the ...

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FAST COMPUTATION OF ALL PAIRS OF GEODESIC DISTANCES

FAST COMPUTATION OF ALL PAIRS OF GEODESIC DISTANCES

... As for the geodesic extrema method, we compare the filling rates of the method based on the filling rate of the distances array and the spiral method versus the number of propagations (fig. 8). We notice that the ...

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Apparent Diffusion Coefficient Mapping Using a Multi Shot Spiral MRI Sequence of the Rat Brain

Apparent Diffusion Coefficient Mapping Using a Multi Shot Spiral MRI Sequence of the Rat Brain

... ratio. Spiral MRI sequence (SPIRAL) has characteristics similar to these of EPI, but it has rarely been used for diffusion-weighted imaging ...multi-shot spiral acquisition MRI for apparent diffusion ...

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Implantable In Body Antenna Design At Medical Implant Communication Service Band For Telemedicine Application

Implantable In Body Antenna Design At Medical Implant Communication Service Band For Telemedicine Application

... 4.8 b Return Loss Of Antenna for Three Different Number of Spiral 77 4.9 a Bandwidth of Spiral Shape Micro Strip Antenna 78 4.9 b Reference Impedance of Spiral Shape Micro Strip Antenna [r] ...

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