Spleen Focus Forming Virus
Genetic Structure of Rauscher Spleen Focus-Forming Virus
... 1217-1222 0022-538X/83/031217-06$02.00/0 Copyright C 1983, American Society for Microbiology Genetic Structure of Rauscher Spleen Focus-Forming Virus RICHARD BESTWICK,1 MARTIN RUTA,1 ANN[r] ...
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Erythroblast Transformation by the Friend Spleen Focus-Forming Virus Is Associated with a Block in Erythropoietin-Induced STAT1 Phosphorylation and DNA Binding and Correlates with High Expression of the Hematopoietic Phosphatase SHP-1
... Friend spleen focus-forming virus (SFFV) results in a multistage ...rare virus-infected erythroid cell that expresses nonphysiological levels of the myeloid transcription factor ...
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Glycoprotein encoded by the Friend spleen focus-forming virus.
... 564 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The Friend spleen focus-forming virus F-SFFV released from cultured erythroleukemia cells cell line F4-6/K was clone[r] ...
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Cell surface activation of the erythropoietin receptor by Friend spleen focus-forming virus gp55.
... Friend spleen focus-forming virus (SFFV), induces erythroid cell proliferation through its interaction with the erythropoietin receptor ...
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Specific neutralization of defective spleen focus-forming virus in Friend virus complex by rat antiserum.
... With regard to the Friend virus FV -complex 5 consisting of defective spleen focus-forming virus SFFV and a helper murine leukemia virus Friend-associated murine leukemia virus [F-MuLV] [r] ...
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The potent enhancer activity of the polycythemic strain of spleen focus-forming virus in hematopoietic cells is governed by a binding site for Sp1 in the upstream control region and by a unique enhancer core motif, creating an exclusive target for PEBP/CBF.
... the spleen focus-forming virus (SFFVp) contains the most potent murine retroviral enhancer configuration known so far for gene expression in myeloerythroid hematopoietic ...leukemia ...
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Role of Phosphatidylinositol 3-Kinase in Friend Spleen Focus-Forming Virus-Induced Erythroid Disease
... Friend spleen focus-forming virus (SFFV) leads to acute erythroid hyperplasia in mice due to expression of its unique envelope glycoprotein, ...
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Defective Friend Spleen Focus-Forming Virus: Interfering Properties and Isolation Free from Standard Leukemia-Inducing Helper Virus
... HETTRICK Department of Microbiology and Pathology, Boston University School of Medicine, Boston, Massachusetts 02118 Defective Friend spleen focus-forming virus SFFV is able to interfere[r] ...
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Identification of a spleen focus-forming virus in erythroleukemic mice infected with a wild-mouse ecotropic murine leukemia virus.
... 230-238 0022-538X/83/040230-09$02.00/0 Copyright © 1983, American Society for Microbiology Identification of a Spleen Focus-Forming Virus in Erythroleukemic Mice Infected with a Wild-Mou[r] ...
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Molecular cloning of biologically active Rauscher spleen focus-forming virus and the sequences of its env gene and long terminal repeat.
... Friend strain of spleen focus-forming virus: a recombinant between mouse type C ecotropic viral sequences and sequences related to xenotropic virus.. Friend strain of spleen focus-formin[r] ...
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Intracellular transport and leukemogenicity of spleen focus-forming virus envelope glycoproteins with altered transmembrane domains.
... We constructed a chimeric envelope gene which codes for a molecule with an external domain derived from the SFFV envelope gene and membrane-spanning and cytoplasmic domains derived from [r] ...
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Reduced leukemogenicity caused by mutations in the membrane glycoprotein gene of Rauscher spleen focus-forming virus.
... Southern blot analysis of unintegrated proviral DNA from cells infected with either wild-type R-SFFV lane 2 or mutant R-SFFVs clones 3-25 and 4-3 In lanes 3 and 4.. Infection conditions [r] ...
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Spleen focus-forming virus: specific neutralization by antisera to certain gag gene-encoded proteins.
... Virus stocks were prepared as 10% wt/vol spleen perfusates in phosphate-buffered saline; those containing SFFV were harvested from adult mice injected 2 weeks previously with a high dose[r] ...
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Three laboratory strains of spleen focus-forming virus: comparison of their genomes and translational products.
... To determine whether SFFV isolated from other strains of the Friend virus complex also encode for an MCF-related env gene product, we analyzed extracts of nonproducer cells containing SF[r] ...
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Analysis of spleen focus-forming virus-specific RNA sequences coding for spleen focus-forming virus-specific glycoprotein with a molecular weight of 55,000 (gp55).
... P47 formed in vitro was found to be structurally related to the protein portion of a glycoprotein, gp55, specifically found in SFFV-infected cells in vivo., It is concluded from the resu[r] ...
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Loss of pathogenicity of spleen focus-forming virus after pseudotyping with Akv.
... This helper-free SFFV can infect erythropoietic target cells, as shown by its erythroid burst-inducing activity in vitro, but it cannot induce spleen foci or FV disease in normal adult m[r] ...
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Analysis of translational products of Friend strain of spleen focus-forming virus.
... AARONSON' * Laboratory of Cellular and Molecular Biology' and Laboratory of Tumor Virus Genetics,2 National Cancer Institute, Bethesda, Maryland 20014 We have analyzed normal rat kidney [r] ...
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Conversion of Friend mink cell focus-forming virus to Friend spleen focus-forming virus by modification of the 3' half of the env gene.
... The recombinant plasmid containing the mutant F-SFFVp genome in which the F-MCFV env-related sequence in the 5' half of the gp55 sequence was substituted by the corresponding ecotropic e[r] ...
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Recovery of biologically active spleen focus-forming virus from molecularly cloned spleen focus-forming virus-pBR322 circular DNA by cotransfection with infectious type C retroviral DNA.
... Goat anti-Rauscher MuLV gp70 serum was used to precipitate cells cotransfected with undigested pBR322-SFFV recombinant DNA plus infectious FMuLV clone 57 DNA lane 1, cloned SFFV DNA rele[r] ...
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Cas spleen focus-forming virus. II. Further biological and biochemical characterization.
... RNA was prepared from an AKR thymoma lane 1, NIH 3T3 cells infected with Cas-Br-M ecotropic MuLV lane 2, erythroleukemic spleens from NIH Swiss mice infected with FV-P Mirand lane 3, FV-[r] ...
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