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Spontaneous pain

Manganese enhanced magnetic resonance imaging depicts brain activity in models of acute and chronic pain: a new window to study experimental spontaneous pain?

Manganese enhanced magnetic resonance imaging depicts brain activity in models of acute and chronic pain: a new window to study experimental spontaneous pain?

... and pain behaviour reported herein indicate that in vivo MEMRI at 7 T is sensitive to cumulative neural e ff ects of pain behaviour in awake freely moving ...pinning spontaneous pain in ...

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Effects of NB001 and gabapentin on irritable bowel syndrome-induced behavioral anxiety and spontaneous pain

Effects of NB001 and gabapentin on irritable bowel syndrome-induced behavioral anxiety and spontaneous pain

... discomfort, spontaneous pain, colorectal hypersensitivity and bowel ...IBS-induced spontaneous pain and behavioral ...assessed spontaneous pain and anxiety behaviors in an adult ...

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Repeated administration of mazindol reduces spontaneous pain-related behaviors without modifying bone density and microarchitecture in a mouse model of complete Freund’s adjuvant-induced knee arthritis

Repeated administration of mazindol reduces spontaneous pain-related behaviors without modifying bone density and microarchitecture in a mouse model of complete Freund’s adjuvant-induced knee arthritis

... decreases spontaneous pain in CFA-induced arthritis and increases the locomotor activity at the highest dose ...in spontaneous flinches (A) and time spent guarding (B) with the three different ...

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Reproduction of overall spontaneous pain pattern by manual stimulation of active myofascial trigger points in fibromyalgia patients

Reproduction of overall spontaneous pain pattern by manual stimulation of active myofascial trigger points in fibromyalgia patients

... A two-way analysis of variance (ANOVA) was used to compare the differences in local and referred pain areas between patient and control groups. If significant, post- hoc pair-wise multiple comparisons were ...

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Somatosensation in OA: exploring the relationships of pain sensitization, vibratory perception and spontaneous pain

Somatosensation in OA: exploring the relationships of pain sensitization, vibratory perception and spontaneous pain

... “ spontaneous pain ” in our study is not necessarily a validated ques- tionnaire tool, and it may be subject to variations in in- terpretation [31], it nonetheless appeared to be attested to frequently in ...

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Alkali burn induced corneal spontaneous pain and activated neuropathic pain matrix in the central nerve system in mice

Alkali burn induced corneal spontaneous pain and activated neuropathic pain matrix in the central nerve system in mice

... Corneal alkali burn cause nerve fibers injury in cauterized area 236. The densities of nerve fibers in subbasal level of the cornea were detected by anti- β[r] ...

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Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain

Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain

... OD1-induced spontaneous pain model can be used to assess the in vivo activity of compounds when delivered by both the intraplantar and a systemic ...

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Headache and mechanical sensitization of human pericranial muscles after repeated intake of monosodium glutamate (MSG)

Headache and mechanical sensitization of human pericranial muscles after repeated intake of monosodium glutamate (MSG)

... significant. Spontaneous pain, PPT, PPTol, BP, HR, and glutamate concentration were analyzed with 3-way repeated measurement (RM) analyses of variance (ANOVAs) with intervention (MSG ...

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EFFECT OF ZONISAMIDE ON CHRONIC CONSTRICTION INJURY INDUCED NEUROPATHIC PAIN IN MALE SD RATS

EFFECT OF ZONISAMIDE ON CHRONIC CONSTRICTION INJURY INDUCED NEUROPATHIC PAIN IN MALE SD RATS

... in pain where as chemical allodynia produces pain due to chemokine ...neuropathic pain to the same therapy have been seen ...on spontaneous pain, the effect on mechanical and chemical ...

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Rational treatment of chemotherapy-induced peripheral neuropathy with capsaicin 8% patch: from pain relief towards disease modification

<p>Rational treatment of chemotherapy-induced peripheral neuropathy with capsaicin 8% patch: from pain relief towards disease modification</p>

... Results: Patients reported signi fi cant reduction in spontaneous pain (mean NPRS: − 1.27; 95% CI 0.2409 to 2.301; p=0.02), touch-evoked pain ( − 1.823; p=0.03) and cold-evoked pain ( − 1.456; ...

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Spontaneous inflammatory pain model from a mouse line with N-ethyl-N-nitrosourea mutagenesis

Spontaneous inflammatory pain model from a mouse line with N-ethyl-N-nitrosourea mutagenesis

... inflammatory pain, the present animal model of spontaneous pain has a longer duration of ...carrageenan-induced pain have been recognized as short-term inflammatory pain ...inflammatory ...

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Efficacy of isothiocyanate-based compounds on different forms of persistent pain

Efficacy of isothiocyanate-based compounds on different forms of persistent pain

... persistent pain related to neuropathy or articular diseases is unsatisfactory, due to the large number of unresponsive patients and side ...and spontaneous pain induced by nerve injury and ...

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Differential drug effects on spontaneous and evoked pain behavior in a model of trigeminal neuropathic pain

Differential drug effects on spontaneous and evoked pain behavior in a model of trigeminal neuropathic pain

... the two different classes of neuropathic sensory dysfunctions in the IoN-CCI model follow a different time course and sug- gested that this may indicate that different neuropathological mechanisms underlie these ...

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PKCδ targeted intervention relieves chronic pain in a murine sickle cell disease model

PKCδ targeted intervention relieves chronic pain in a murine sickle cell disease model

... chronic pain severity, were on the same order of magnitude as those in mice after spinal nerve ligation (11), which is in agreement with the clinical obser- vation of high pain scores in SCD ...to ...

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A retrospective study on persistent pain after childbirth in the Netherlands

A retrospective study on persistent pain after childbirth in the Netherlands

... a spontaneous vaginal delivery, 42 an instrumental vaginal delivery, 95 a (secondary) CS, and there were 12 missing ...labor pain was 133 and 119, respectively; 199 women received no pain ...

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A retrospective study on persistent pain after childbirth in the Netherlands

A retrospective study on persistent pain after childbirth in the Netherlands

... the Netherlands were randomized to RPCA (30 µ g bolus with a lockout time of 3 minutes) or EA (either with ropivacaine/ sufentanil, bupivacaine/sufentanil, levobupivacaine/sufentanil, or bupivacaine/fentanyl), should ...
Spontaneous Intracranial Hypotension Treated with a Targeted CT-Guided Epidural Blood Patch

Spontaneous Intracranial Hypotension Treated with a Targeted CT-Guided Epidural Blood Patch

... neck pain or stiffness, nausea, or ...facial pain, facial weakness, facial spasm, dysgeusia, parkinsonism, or ...interscapular pain, quadriplegia, upper extremity radicular symptoms, ...

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BONDING AND ATTACHMENT EXPERIENCE AMONG POSTNATAL MOTHERS WITH SPONTANEOUS CHILDBIRTH

BONDING AND ATTACHMENT EXPERIENCE AMONG POSTNATAL MOTHERS WITH SPONTANEOUS CHILDBIRTH

... A study of Nilsson et al. (2013) found that mothers feel so happy when they are able to give birth to children normally, so that it is an incomparable experience. An indescribable feeling of happiness occurs when the ...

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EFFICACY OF PLANTAR IONTOPHORESIS WITH AQUEOUS SOLUTION OF GUGGULU RESIN IN THE MANAGEMENT OF PADAKANTAKA (PLANTAR FASCIITIS): A PILOT STUDY

EFFICACY OF PLANTAR IONTOPHORESIS WITH AQUEOUS SOLUTION OF GUGGULU RESIN IN THE MANAGEMENT OF PADAKANTAKA (PLANTAR FASCIITIS): A PILOT STUDY

... Pada-kantaka is a pathological condition caused by the vitiated vata and kapha. Aggravated vata takes ashraya in gulfa sandhi & padatala leading to the development of Pada-kantaka. As per the textual references ...

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Ultrasound assessment of haemoperitoneum in ectopic pregnancy: derivation of a prediction model

Ultrasound assessment of haemoperitoneum in ectopic pregnancy: derivation of a prediction model

... The diagnostic values of the variables associated with hae- moperitoneum ≥ 300 ml in the univariate analysis are shown in Table 3. Three variables had a high sensitivity with sufficiently low negative LR: any pelvic ...

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