Standardisation of the cholesteryl ester analysis method
Cholesteryl ester transfer protein inhibitors for dyslipidemia: focus on dalcetrapib
... This paradox was explained by putative off-target effects not related to CETP inhibition that were specific to torcetrapib. Subsequently, three newer CETP inhibitors, namely dalcetrapib, anacetrapib, and evacetrapib, ...
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Investigation of the physical properties of cholesteryl ester liquid crystal and the interaction with cells
... 1.5 Thesis organisation This thesis is divided into five chapters. Chapter 1 provides an overview of this project and the objectives, scopes and problem statement of the research. Chapter 2 reveals on the CELC background ...
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The effect of cholesteryl ester transfer protein on pancreatic beta cell dysfunction in mice
... For analysis of pancreatic islet apoptosis, double staining of in situ cell death detection fluorescence and insulin fluorescent immu- nohistochemistry were ...
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Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition
... When examining triglycerides in apolipoprotein B–containing particles, CETP expression lowering allele associated with lower circulating triglyceride concentrations in VLDL and IDL subclasses, whereas HMGCR expression ...
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Cholesteryl ester transfer-protein modulator and inhibitors and their potential for the treatment of cardiovascular diseases
... pooled analysis of the rating atherosclerotic disease change by imaging with a new CETP inhibitor) and the ILLUMINATE studies indicated a relationship between increased blood pressure and thickening carotid vessel ...
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Cholesteryl ester transfer protein: A potential target for the treatment of coronary artery disease
... The analysis of the CETP primary sequence (476 amino acids) indicates that the mature protein is composed of 45% of nonpolar residues, suggesting it to be highly hydrophobic in ...
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Influence of time dependent factors to the phases and poisson’s ratio of cholesteryl ester liquid crystals
... least-squares method, the Poisson’s ratio of the CELC and LLC (25 o C) was characterised by a linearised regime up to 160 % of transverse strain (log ε 1 = ...
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Kinetic parameters for high density lipoprotein apoprotein AI and cholesteryl ester transport in the hamster
... detailed analysis of the kinetics of HDL apo AI and cholesteryl ester uptake by the various or- gans of the body in ...and cholesteryl ester transport were studied separately as these ...
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PHARMACOGENOMIC STUDIES OF CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) GENOTYPES IN SUSPECTED CAD PATIENTS
... of Cholesteryl ester transfer protein (CETP) gene polymorphism rs708272 (Taq1B) with cardiovascular diseases, since variations in the CETP gene alters the HDL-C ...PCR-RFLP method followed by agarose ...
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I405V and -629C/A Polymorphisms of the Cholesteryl Ester Transfer Protein Gene in Patients with Coronary Artery Disease
... DNA analysis was collected from the subjects after an overnight ...direct method and apolipoprotein A1 and apolipoprotein B levels were determined by immunoturbidimeteric ...
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Atherogenic diet increases cholesteryl ester transfer protein messenger RNA levels in rabbit liver
... https://doi.org/10.1172/JCI114446. Cholesteryl ester transfer activity is increased in plasma of cholesterol-fed ...measured cholesteryl ester transfer protein (CETP) mass by RIA and CETP mRNA ...
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A Molecular and Biochemical Study for Cholesteryl Ester Transfer Protein (CETP) Taq1B in Iraqi Patients with Hyperlipidemia
... Abstract: Cholesteryl ester transfer protein gene contains some single nucleotide polymorphisms, which have been associated with serum high-density lipoprotein concentration and other ...of ...
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Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: Effects on stability, peroxidation, and cell uptake
... for cholesteryl linoleate than for the other preparations from day 1 onwards, tending to increase further after day 30 of the study ...both cholesteryl oleate and cholesteryl stearate soon after ...
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Diagnostic Algorithm for Cholesteryl Ester Storage Disease: Clinical Presentation in 19 Polish Patients. What Is New
... spot method, introduced by Hamilton in 2012, is very useful in clinical practice and helps to effectively discriminate between individuals with LAL-D and unaffected controls ...
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Patient considerations and clinical impact of cholesteryl ester transfer protein inhibitors in the management of dyslipidemia: focus on anacetrapib
... Further analysis of this study revealed that the concentrations of HDL-C achieved in the gemfibrozil treatment group were strongly correlated with significant reduc- tions in coronary ...
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Ciprofibrate increases cholesteryl ester transfer protein gene expression and the indirect reverse cholesterol transport to the liver
... Total liver RNA was extracted from ~200 mg of tissue using Trizol reagent (Invitrogen, Grand Island, NY). The integrity of the RNA was checked in tris-borate 1.2% aga- rose gels stained with ethidium bromide. The amount ...
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The role of common variants of the cholesteryl ester transfer protein gene in left main coronary artery disease
... The results are expressed as mean ± standard deviation (SD) or as median and interquartile range (IQR) accord- ing to normality of continuous variables. All qualitative variables are presented as absolute or relative ...
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Correlation between the level of cholesteryl ester transfer protein in follicular fluid with fertilization rates in IVF/ ICSI cycles
... Statistical analysis Values are presented as mean± ...Multivariate analysis of variance test were used for comparing means and ratios in different ...significant. Analysis was carried out using SPSS ...
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Association of Cholesteryl Ester Transfer Protein Gene Taqib Polymorphism and the Associated Phenotype Variation with Coronary Artery Disease.
... univariate analysis. In multivariate analysis, when controlling statistically for risk factors such as hypertension, diabetes, and dyslipidemia, obesity is not found to be an independent risk ...
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Macrophage specific transgenic expression of cholesteryl ester hydrolase significantly reduces atherosclerosis and lesion necrosis in Ldlr–/– mice
... 60-mm, f/2.8 Macro Lens. Total area and the area occupied by the lesions in the aortic arch and thoracic and abdominal aortae was determined using BIOQUANT Image Analysis 98 software. The person quantifying the ...
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