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statin treatment

Statin treatment affects cytokine release and phagocytic activity in primary cultured microglia through two separable mechanisms

Statin treatment affects cytokine release and phagocytic activity in primary cultured microglia through two separable mechanisms

... beads. Treatment of microglia with 2 mM mβcd signifi- cantly reduced both the proportion of active phagocytes and the mean uptake per phagocyte, both of which were fully recovered after treatment with ...

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Impact of Statin Treatment on Strut Coverage after Drug Eluting Stent Implantation

Impact of Statin Treatment on Strut Coverage after Drug Eluting Stent Implantation

... of statin with the vascular healing ...received statin therapy. Therefore, we could not evaluate the effect of statin therapy on strut coverage by making comparisons with pa- tients who did not ...

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Statin treatment and adherence to national cholesterol guidelines after ischemic stroke

Statin treatment and adherence to national cholesterol guidelines after ischemic stroke

... from statin therapy. The authors aimed to determine the rate of statin use, its predictors, and the achievement of national guideline target lipid goals among ischemic stroke ...initiating statin ...

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Discontinuation of Statin Treatment in Relation to Chronic Diseases and Laboratory Findings

Discontinuation of Statin Treatment in Relation to Chronic Diseases and Laboratory Findings

... of statin treatment, especially with respect to clinical characteristics and adverse effect measured by clinical laboratory tests indicating muscle damage (plasma creatine kinase, CK) and liver AEs (plasma ...

7

Differences in discontinuation of statin treatment in women and men with advanced cancer disease

Differences in discontinuation of statin treatment in women and men with advanced cancer disease

... prescribed statin treatment for more than 1 month during the last 10 ...discontinued statin use before being diagnosed with cancer and was not included in the ...discontinued statin ...

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The association of HDL-apoCIII with coronary heart disease and the effect of statin treatment on it

The association of HDL-apoCIII with coronary heart disease and the effect of statin treatment on it

... of statin treatment on lipid markers in CHD patients with DM or ...of statin treatment on apoCIII markers in patients with DM (n = ...although statin treatment re- duces the risk ...

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Adherence to statin treatment following a myocardial infarction: an Italian population-based survey

Adherence to statin treatment following a myocardial infarction: an Italian population-based survey

... a statin prescrip- tion at hospital ...with treatment during the follow-up, only 1,431 had an adherence to statins ...to treatment. An important factor in long-term adherence to statin ...

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Statin Treatment Modulates Clinical Response to Amodiaquine in Acute Uncomplicated Falciparum Malaria

Statin Treatment Modulates Clinical Response to Amodiaquine in Acute Uncomplicated Falciparum Malaria

... Pharma AG, Basel-Switzerland) was used to salvage subjects who presented with recrudescence or treatment failure and eventually withdrawn from the study. The Ar temether component was given as 3.2mg/kg/d while the ...

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High HbA1c levels correlate with reduced plaque regression during statin treatment in patients with stable coronary artery disease: Results of the coronary atherosclerosis study measuring effects of rosuvastatin using intravascular ultrasound in Japanese

High HbA1c levels correlate with reduced plaque regression during statin treatment in patients with stable coronary artery disease: Results of the coronary atherosclerosis study measuring effects of rosuvastatin using intravascular ultrasound in Japanese subjects (COSMOS)

... As the relationship between the change in plaque vol- ume and HbA1c was mainly observed in diabetic patients, and not in non-diabetic patients, HbA1c seems to be an important determinant of plaque regression in diabetic ...

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Statin Treatment in Diabetes Mellitus

Statin Treatment in Diabetes Mellitus

... In clinical trials, the risk of developing myopathy and rhabdomyolysis seems to be increased in patients receiving statins concomitantly with other agents metab- olized through the CYP enzyme system, particularly CPY3A4. ...

5

Preoperative statin is associated with decreased operative mortality in high risk coronary artery bypass patients

Preoperative statin is associated with decreased operative mortality in high risk coronary artery bypass patients

... receiving statin treatment, likely reflecting more focused cardiac care following the pre- vious ...of statin treatment was associated with an increase in mortality in the subset of high risk ...

5

Survival benefit of a low ratio of visceral to subcutaneous adipose tissue depends on LDL clearance versus production in sepsis

Survival benefit of a low ratio of visceral to subcutaneous adipose tissue depends on LDL clearance versus production in sepsis

... clearance. Statin therapy lowers LDL in the circula- tion primarily by inhibition of LDL production in hepato- cytes ...[12–14]. Statin treatment is common and therefore sufficiently prevalent in ...

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Pilot randomized trial of short-term changes in inflammation and lipid levels during and after aspirin and pravastatin therapy

Pilot randomized trial of short-term changes in inflammation and lipid levels during and after aspirin and pravastatin therapy

... longer-term statin use; however, one previous study assessed short-term treat- ment and inflammation ...During statin treatment, mean hsCRP de- creased from ...that statin-mediated changes in ...

7

Anti Inflammatory Effects of Statins in Cardiac Surgery Patients

Anti Inflammatory Effects of Statins in Cardiac Surgery Patients

... Tumor necrosis factor alpha (TNF-α) is an important pro-inflammatory cytokine and potent chemoattractant for neutrophils by inducing the expression of adhesive mole- cules on the endothelial cells and facilitating their ...

8

Statin use in Primary Prevention of Coronary Heart Disease: Issues and Perspectives

Statin use in Primary Prevention of Coronary Heart Disease: Issues and Perspectives

... management system (SMS) focused on describing a primary prevention of coronary heart disease in the intermediate-risk population and encouraged par ticipants to discuss their concer ns about cholesterol; including OTC ...

5

The association of the PCSK9 rs562556 polymorphism with serum lipids level: a meta-analysis

The association of the PCSK9 rs562556 polymorphism with serum lipids level: a meta-analysis

... The main function of PCSK9 was binding the LDLR and promoting LDLR degradation in lysosome. It interfaced the recycling of LDLR to cell surface thus regulated the serum LDL-C level. Statins inhibited the cellular biosyn- ...

8

Statin use and risk of haemorrhagic stroke in a community-based cohort of postmenopausal women: an observational study from the Women's Health Initiative

Statin use and risk of haemorrhagic stroke in a community-based cohort of postmenopausal women: an observational study from the Women's Health Initiative

... of statin treatment in patients with a history of cerebrovascular disease showed an increased risk of HS persisting even after excluding patients with a HS as the entry ...Cholesterol Treatment ...

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A Large Grade 5 Mobile Aortic Arch Atheromatous Plaque: Cause of Cerebrovascular Accident

A Large Grade 5 Mobile Aortic Arch Atheromatous Plaque: Cause of Cerebrovascular Accident

... and statin treatment for patients with an ischemic stroke and evidence for an aortic arch atheroma ...endovascular treatment with angioplasty or stenting have been reported, concerns about ...

5

Anti inflammatory and anti lipemic effect of statin therapy in coronary artery disease patients with calcium calcification

Anti inflammatory and anti lipemic effect of statin therapy in coronary artery disease patients with calcium calcification

... before treatment was ...of statin treatment, GII ...of statin treatment (6-8 months) had a reduction effect on the serum levels of hs-CRP (GII; ...before treatment of the same ...

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A Case of Age Related Macular Degeneration Responding to a Statin – Perspective for a New Treatment

A Case of Age Related Macular Degeneration Responding to a Statin – Perspective for a New Treatment

... Taking into account the mechanisms of disease in AMD [2,3] and the mechanism of action of atorvastatin which aside from lowering LDL- cholesterol also improves endothelial function by a direct so called pleiotropic ...

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