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Statistical concepts and issues with subgroup analyses

MSCA Introduction to Statistical Concepts

MSCA Introduction to Statistical Concepts

... important issues in applied time series analysis: a solid knowledge of time series models and their theoretical properties; how to analyze time series data by using mainstream statistical software; ...

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MSCA Introduction to Statistical Concepts

MSCA Introduction to Statistical Concepts

... important issues in applied time series analysis: a solid knowledge of time series models and their theoretical properties; how to analyze time series data by using mainstream statistical software; ...

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Subgroup analyses in confirmatory clinical trials: time to be specific about their purposes

Subgroup analyses in confirmatory clinical trials: time to be specific about their purposes

... positive subgroup finding can be considered confirma- ...reach statistical signifi- ...biomarker-negative subgroup are identified. Historically, these analyses are not common for phase III ...

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Investigating Statistical Concepts, Applications, and Methods

Investigating Statistical Concepts, Applications, and Methods

... of statistical investigations from start to finish, over and over again in new ...present issues of data collection, data description, and statistical inference all in the first ...

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A meta-epidemiological study of subgroup analyses in cochrane systematic reviews of atrial fibrillation

A meta-epidemiological study of subgroup analyses in cochrane systematic reviews of atrial fibrillation

... the subgroup effects identified in these reviews are that most effects were identified be- tween studies rather than within studies and only half of the subgroup effects identified were consistent across ...

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Statistical Analyses of Diverse Issues in Sustainable Agriculture

Statistical Analyses of Diverse Issues in Sustainable Agriculture

... For the Piedmont region of NC, there were a number of variables of which changes were predictive of changes in the number of farms. A small amount of the time increases in the amount of family assistance being paid out ...

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Model-Based Recursive Partitioning for Subgroup Analyses

Model-Based Recursive Partitioning for Subgroup Analyses

... Keywords: subgroup analysis, personalized medicine, treatment efficacy, permutation test, amyotrophic lateral sclerosis 1 Introduction With the rise of personalised medicine, the search for individual treatments ...

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Case Analyses of Accounting Concepts and Methodologies

Case Analyses of Accounting Concepts and Methodologies

... e. A deferred income tax valuation allowance refers to the portion of deferred income tax assets that are deemed unlikely to be realized. If a company predicts that it is more likely than not, the firm will institute a ...

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Exacerbation heterogeneity in COPD: subgroup analyses from the FLAME study

Exacerbation heterogeneity in COPD: subgroup analyses from the FLAME study

... The statistical methods used to analyze the endpoints have been described ...the statistical analyses. The analyses were performed on the full analysis set, which included all randomized ...

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Disability: concepts and statistical information

Disability: concepts and statistical information

... These questions regard level of difficulty and autonomy in daily life activities (such as walking, walking up and down stairs, bending and kneeling down, getting in and out of bed or chair, dressing yourself, washing and ...

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Subgroup analyses and investigations of treatment effect heterogeneity in clinical dose-finding trials

Subgroup analyses and investigations of treatment effect heterogeneity in clinical dose-finding trials

... a statistical perspective subgroup analyses in the settings described above are chal- ...group analyses (Lagakos (2006); Wang et ...population. Statistical tests to detect possible sub- ...

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Methods for estimating subgroup effects in cost-effectiveness analyses that use observational data.

Methods for estimating subgroup effects in cost-effectiveness analyses that use observational data.

... This study is a rare example of a full economic evaluation alongside a crossover trial. This raised certain methodologic issues, in particular that all the results are based on paired differences within patients, ...

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International trade in services: issues and concepts

International trade in services: issues and concepts

... The approach to services taken in the economic literature has pointed to many aspects of services and of trade in services, but has failed to come up with an economic definition (as opposed to the statistical ...

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Interpretation of subgroup analyses in systematic reviews: A tutorial

Interpretation of subgroup analyses in systematic reviews: A tutorial

... a subgroup analysis was performed to investigate whether the intensiveness of Treatment A modifies treatment effect, and this subgroup analysis demonstrated a statistically significant treatment ...

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Analyses: Statistical Measures

Analyses: Statistical Measures

... The SDANN is the standard deviation of all the 5-minute NN interval (normal RR) means (i.e., the standard deviation of 288 NN means), while the SDNN-index is the mean of all the 5-minut[r] ...

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A Critical Review of Graphics for Subgroup Analyses in Clinical Trials

A Critical Review of Graphics for Subgroup Analyses in Clinical Trials

... for subgroup analysis starts with the full population that branches into two or more items, corresponding to the levels of the first subgroup-defining ...the subgroup sample ...

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Statistical Analyses of ASE Noise

Statistical Analyses of ASE Noise

... To avoid the complex noise probability evolution in fibers, in [5] [6] [10], au- thors directly calculated the system performance (BER, Q) by the SNR which was the function of power. This is an approach by measuring ...

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Antigenic and genetic analyses of human rotavirus with dual subgroup specificity

Antigenic and genetic analyses of human rotavirus with dual subgroup specificity

... The reactivity pattern of these four HRV isolates with three monoclonal antibodies (MAbs) directed to an outer capsid protein, VP4, and with one MAb directed to an inner capsid protein, [r] ...

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ABOUT THE CONCEPTS OF STATISTICAL MEASUREMENTS

ABOUT THE CONCEPTS OF STATISTICAL MEASUREMENTS

... There are described four concepts of the statistical measurements and the methods realizing these concepts for processing the observations. There are adduced the examples in which correct and ...

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Bioequivalence: An overview of statistical concepts

Bioequivalence: An overview of statistical concepts

... S. Rani, A. Pargal * ABSTRACT Bioequivalence (BE) means the absence of a greater-than-allowable difference between the sys- temic bioavailability of a test product and that of a reference product. Studies to test the BE ...

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