Stellate cells
Secreted phospholipase A2 of Clonorchis sinensis activates hepatic stellate cells through a pathway involving JNK signalling
... LX-2 cells could be ...LX-2 cells were incubated with 50 μg/ml of CsESPs ...hepatic stellate cells in vivo, and cause accumu- lation of collagen which leads to liver ...Hepatic stellate ...
12
Hepatic stellate cells in liver development, regeneration, and cancer
... hepatic stellate cells in liver regenera- tion will be facilitated by the availability of multiple animal mod- els, which are likely to yield complementary ...hepatic stellate cells in vitro, ...
10
Hepatic stellate cells increase in Toxoplasma gondii infection in mice
... Methods: Acute infection was induced in fifteen 30-day-old normal Swiss albino mice. The mice were infected by intraperitoneal inoculation of 5000 T. gondii RH strain tachyzoites. The mice were sacrificed in groups of 5 ...
6
Discovery of Aptamer Ligands for Hepatic Stellate Cells Using SELEX
... We recently discovered a PCBP2 siRNA that can be potentially used for the treatment of liver fibrosis [25, 26]. However, lack of an efficient system to deliver siRNA to hepatic stellate cells still remains ...
14
Hepatic stellate cells contribute to progenitor cells and liver regeneration
... Hepatic stellate cells (HSCs) are characterized by exception- ally high amounts of retinoids in their quiescent ...collagen-producing cells in the liver, which are responsible for fibrogenesis in ...
14
Hepatic stellate cells: central modulators of hepatic carcinogenesis
... cancer cells and their ...Hepatic stellate cells (HSC) are the major source of extracellular proteins during fibrogenesis, and may directly, or via secreted products, contribute to tumour initiation ...
13
Roles of hepatic stellate cells in liver inflammation: a new perspective
... Hepatic stellate cells (HSCs) are pericytes residing in the perisinusoidal space, between sinusoidal endothelial cells and hepatocytes, store vitamin A, and regulate sinusoidal ...liver cells, ...
6
Hepatic stellate cells and parasite induced liver fibrosis
... hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important event in liver fibrogenesis and has been well investigated over the last few years in a number of liver ...
7
Transcriptome Profiles and Gene Expression of Min6 Cells Are Altered by Pancreatic Stellate Cells
... The functioning of pancreatic β -cells, which perform a pivotal role in maintain- ing glucose homeostasis, is influenced by various factors including nutritional [1] [2] [3], metabolic [4] [5] and hormonal factors ...
16
Experimental techniques for the isolation of pancreatic stellate cells
... cultured cells that have been cryopreserved in Dr Costello’s ...primary cells has revealed three distinct cell ...pancreatic stellate cell, various difficulties encountered during characterisation ...
148
Multiplex quantitative analysis of stroma-mediated cancer cell invasion, matrix remodeling, and drug response in a 3D co-culture model of pancreatic tumor spheroids and stellate cells
... tumor cells and is in- volved in the regulation of ECM remodeling during tumor invasion [52, ...cancer cells and PSCs were accompanied by increased expression of TGF-β1 ...cancer cells and ...
14
Anti fibrotic effects of phenolic compounds on pancreatic stellate cells
... pancreatic stellate cells (PSCs) play a critical role in the development of fibrogenesis in the pancreas, which plausibly a dynamic process of transition to pancre- atic ductal adenocarcinoma ...
7
<p>Targeting Pancreatic Cancer Cells and Stellate Cells Using Designer Nanotherapeutics in vitro</p>
... (stellate cells) CAF-19 were used to assess the effects of nanoconjugate treat- ...CAF-19 cells were a kind gift from ...CAF-19 cells were approved by the institutional review ...pancreatic ...
13
Hepatic stellate cells and parasite induced liver fibrosis
... new cells lines of human ...the cells to parasite antigens using techniques such as microarrays, RNAi and flow cytometry could reveal new insights into the process of parasite-induced ...
8
Synaptic inhibition of cerebellar Purkinje cells
... Lugaro cells, since the identification of Lugaro cells solely on the basis of their position in the slice and the shape of their somata, (as described in Chapter 2, section ...Purkinje cells is less ...
312
Distinct roles of neuroepithelial like and radial glia like progenitor cells in cerebellar regeneration
... removes cells from all three ...granule cells (GC) and inhibitory Golgi neurons ...inhibitory stellate cells (S). Neural stem cells are maintained in the dorsomedial part of the ...
11
Cell specific expression of transforming growth factor beta in rat liver Evidence for autocrine regulation of hepatocyte proliferation
... endothelial cells, Kupffer cells (liver macrophages), and lipocytes (Ito or stellate cells) from normal and regenerating ...endothelial cells and Kupffer ...
10
Novel roles for GATAe in growth, maintenance and proliferation of cell populations in the Drosophila renal tubule
... principal cells induce uncontrolled cell proliferation, resulting in tumorous growth with associated altered expression of apoptotic and carcinogenic key ...of stellate cells and migration of renal ...
11
Heterogeneity of cancer-associated fibroblasts and roles in the progression, prognosis, and therapy of hepatocellular carcinoma
... collagen-producing cells, which not only provide mechanical support but also influence tumor cell prolif- eration, apoptosis, migration, invasion, angiogenesis, immune escape, and drug resistance through communi- ...
9
The hepatic stem cell niche and paracrine signaling by mesenchymal cells in support of human hepatic stem cells
... HeLa cells (American Type Culture Collection, Manassas, VA) were used as positive controls, CHAPS buffer with RNase out served as negative control, and heart tissue was used as ...
276