Stem cells and progenitors
Neural Crest Stem Cells/Progenitors and Their Potential Applications in Disease Therapies
... crest progenitors harbor stem cell characteristics with self-renewal capacity and contribute to a variety of differentiated cell types from cranio-facial skeletal tissues to peripheral nervous system in the ...
9
Production of Neural Progenitors from Bone Marrow Mesenchymal Stem Cells
... still progenitors and can be redirected into specific neurons by further treatments [36] [47] ...senchymal stem cells and the possibility of using them for further maturation into highly specialized ...
12
Astrocytes derived from trisomic human embryonic stem cells express markers of astrocytic cancer cells and premalignant stem-like progenitors
... differentiated cells rather than the pluripotent stem ...genitor cells (APCs) suitable for global gene expression profiling using high-density exon-specific ...malignant progenitors for ...
18
Keeping Neural Progenitors on a Short Leash: Distinguishing Intermediate Progenitors from Stem Cells in Developing Drosophila Optic Lobe and Central Brain.
... intermediate progenitors by raising the threshold of response to ...neural progenitors (INPs) needs to be actively maintained after correct specification and identified a novel transcription factor earmuff ...
133
Pericyte-Like Progenitors Show High Immaturity and Engraftment Potential as Compared with Mesenchymal Stem Cells
... Mesenchymal stem cells (MSCs) and pericyte progenitors (PPs) are both perivascular cells with similar multipotential properties regardless of tissue of ...(mesenchymal stem cell medium ...
14
Prospective isolation of NKX2 1–expressing human lung progenitors derived from pluripotent stem cells
... these progenitors for detailed ...pluripotent stem cells (PSCs) in vitro to generate and isolate human primordial lung progenitors that express NKX2-1 but are initially devoid of ...
19
GMP-compatible and xeno-free cultivation of mesenchymal progenitors derived from human-induced pluripotent stem cells
... mesenchymal stem cells are a strong candidate for cell therapies owing to their regenerative potential, paracrine regulatory effects, and immunomodulatory ...mesenchymal stem cells for routine ...
13
A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates
... marrow cells and skeletal muscle progenitors has had only marginal positive benefits in clinical trials, perhaps because adult stem cells have limited ...pluripotent stem cells, ...
16
Role of CD44-dependent pathway in the adhesion and homing of human haemopoietic stem cells and progenitors
... PA STEM CELLS TO FIBRONECTIN AND HYALURONIC ACID AND THE ROLE OF CD44 ...haemopoietic stem cells (HSC) within the bone marrow micro-environment (ME) in close proximity with the stromal ...
211
Cellular and molecular architecture of hematopoietic stem cells and progenitors in genetic models of bone marrow failure
... myeloid progenitors in patients with FA/SDS suggests that these cells feature higher survival or growth properties and possibly harbor some of the initial transformational events that lead to ...GMP-like ...
18
Temporal specification of blood progenitors from mouse embryonic stem cells and induced pluripotent stem cells
... – cells generated from either T-EGFP ESCs (columns 1+2) or Sox17-EGFP ESCs (column 3) were isolated, reaggregated in the indicated conditions for 48 hours and then analyzed for expression of T-EGFP, Sox17-EGFP, ...
11
Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells
... -expressing cells) for both EMP and HSC formation, as deletion with VEC-Cre ERT at any time resulted in essentially no EMPs or no HSCs with two deleted Runx1 ...
12
HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells
... HNF4A-depleted cells may be particularly important because Lokmane et ...ES cells into hepatocyte-like ...ES cells expresses key hepatic transcription factors, including FOXA2, FOXA3, GATA4, GATA6 ...
11
Differentiation of human pluripotent stem cells into two distinct NKX6.1 populations of pancreatic progenitors
... + cells that may have the potential to generate endocrine islet ...+ cells were surrounded, in between, or adjacent to other MPC populations, indicating that these two populations may normally develop close ...
11
Inducible Gata1 suppression expands megakaryocyte erythroid progenitors from embryonic stem cells
... to genetic manipulation, which can be used to reduce the immuno- genicity of platelet progeny and/or engineer them for targeted drug delivery to thrombi. Nakamura et al. showed that ectopic expression of dox-regulated ...
7
Developmental potential of defined neural progenitors derived from mouse embryonic stem cells
... RA-treated cells, they also differentiated into Lim1/2+ interneurons, and into Mnr2+ and Isl1+ motoneurons, extending long axons towards the periphery that were positive both for Trk and p75 neurotrophin ...ES ...
8
Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1
... pancreatic progenitors in vitro under adher- ent culture ...creatic progenitors produced by our protocol (P2-D) efficiently express key markers necessary for generating functional β ...
15
Bobby Sox homology regulates odontoblast differentiation of human dental pulp stem cells/progenitors
... Result: New transcription factors that control the odontoblast differentiation of human DPSCs/progenitors were analyzed using a microarray. The result revealed bobby sox homolog (BBX) to be expressed most strongly ...
9
Cellular responses to Sindbis virus infection of neural progenitors derived from human embryonic stem cells
... infection [29]. It has been recently shown that Coxsackie virus B (CVB3) and Cytomegalovirus (CMV) can both induce apoptosis in hNPCs, and thus achieve optimal viral dissemination [34,35]. Consistent with these re- ...
10
Neuro mesodermal progenitors (NMPs): a comparative study between pluripotent stem cells and embryo derived populations
... allocate cells from the different protocols to our ...few cells allocated to the ...Epi-NMP cells, which are derived from Epi-CE (Materials and Methods), contained the most ...CLE-like cells ...
15