Stimulatory capacity
Mature Dendritic Cells Infected with Herpes Simplex Virus Type 1 Exhibit Inhibited T-Cell Stimulatory Capacity
... Viruses have developed a broad range of mechanisms to escape the host immune response. These include reduced ex- pression of critical antigen epitopes, genetic variations of MHC epitopes, clonal exhaustion, production of ...
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Bordetella adenylate cyclase toxin differentially modulates toll like receptor stimulated activation, migration and T cell stimulatory capacity of dendritic cells
... the capacity of toxin-treated DCs to induce CD4 + and CD8 + T cell ...the capacity of LPS-stimulated DCs to present soluble protein antigen to CD4 + T cells independently of modulation of ...
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Original Article CD11c antigen presenting cells with high B7-H4 expression in active tuberculosis patients are associated with low stimulatory capacity to T cell proliferation
... brane protein belonging to the Ig superfamily with one IgV domain and one IgC domain. The mRNA expression of B7-H4 has been found in both lymphoid and non-lymphoid tissues [6, 7]. However, B7-H4 protein expression is ...
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Phenotypic and functional analysis of monocyte populations in cattle peripheral blood identifies a subset with high endocytic and allogeneic T-cell stimulatory capacity
... High-binding capacity ELISA plates (Maxisorp, Nunc, Denmark) were incubated with coating antibodies overnight at room temperature and then washed and blocked for 1 ...
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Poor Mixed Lymphocyte Reaction Stimulatory Capacity of Leukemic B Cells of Chronic Lymphocytic Leukemia Patients Despite the Presence of Ia Antigens
... In view of the possible role of these cells in the MLR stressed in other reports 21-23 and because they are so decreased in the peripheral blood of most leukemic patients, the stimulator[r] ...
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Characterisation of and T cell responses to the P91A tumour minus antigen.
... amino terminal truncated peptides P91A 15-24 is identified as the peptide with. highest stimulatory capacity, figure 4.3 A.[r] ...
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Three day dendritic cells for vaccine development: Antigen uptake, processing and presentation
... greater capacity to stimulate naïve T cells compared to 7d mDC ...Improved stimulatory capacity of naïve T cells is achieved if mDC are generated using a cocktail that enables their production of ...
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The immunosuppressive factors IL-10, TGF-β, and VEGF do not affect the antigen-presenting function of CD40-activated B cells
... cell-stimulatory capacity of CD40-activated B cells we compared the ability of CD40-activated B cells which were treated with IL-10, TGF-β, or VEGF to induce the proliferation of CFSE- labeled CD4 + or CD8 ...
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Geldanamycin-mediated inhibition of heat shock protein 90 partially activates dendritic cells, but interferes with their full maturation, accompanied by impaired upregulation of RelB
... Moreover, MAPK members JNK [46], and p38 [47] have been shown to positively regulate DC activation, and both kinases interact with HSP90 (JNK [48], p38 [49]). Both MAPK are known to activate PKC, which in turn mediates ...
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Antimicrobial peptides : immunomodulatory and therapeutic potential for use in Atlantic salmon (Salmo salar)
... Functional assays were used to assess the direct stimulatory capacity of antimicrobial peptides on the induction of phagocytosis, cell proliferation, and respiratory burst which play an [r] ...
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Stimulation of TLR4 by recombinant HSP70 requires structural integrity of the HSP70 protein itself
... the stimulatory effect of recombinant ...the stimulatory capacity of this protein preparation on human macrophages, while leaving levels of contaminating endotoxin unchanged relative to appropriate ...
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Growth, Yield and Economics of Broccoli (Brassica oleracea var. Italica) as Influenced by Organic and Inorganic Nutrients
... the stimulatory (capacity to synthesis and secrete thiamine, riboflavin, pyridoxine, cynocobalamine, nicotinic acid, pantothenic acid, IAA and gibberellic acid) therapeutic (ability of the microbes ...
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A Network of Stimulatory and Inhibitory Gα-Subunits Regulates Olfaction in Caenorhabditis elegans
... Figure 2.—ODR-3 and GPA-3 form the major stimulatory signals in odorant detection. Chemotaxis of odr-3 animals and gpa-2 gpa-3 gpa-5 gpa-6 gpa-13 animals (shown as gpa-2 3 5 6 13) shows that ODR-3 is necessary and ...
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Expressions of heparanase and upstream stimulatory factor in hepatocellular carcinoma
... Background: The expression of heparanase (HPSE) was associated with postoperative metastatic recurrence in patients with hepatocellular carcinoma (HCC). The six E-box binding sites in the core promoter of the HPSE gene ...
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The Stimulatory Effects of Medicinal Plants on β2-adrenoceptors of Tracheal Smooth Muscle
... Cumulative log concentration-response curve (CLCRC) of Isop. of guinea pig tracheal chain was performed in presence of the various extracts of medicinal plants and constituents, propranolol and saline. Abbreviations: ...
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Evidence for a Direct Stimulatory Effect of Prostacyclin on Renin Release in Man
... The objectives of this investigation were: a to characterize the time and dose dependence of the effects of prostacyclin PGI2 on renin release in healthy men; b to define whether PGI2-in[r] ...
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The Stimulatory Effect of Platelets and Platelet Membranes on the Procoagulant Activity of Leukocytes
... To determine Their Enhancement of Leukocyte Procoagulant Activity whether increasing amounts of endotoxin produced a One-stage test Tissue cumulative effect, leukocytes were incubated wi[r] ...
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Stimulatory effects of induced phagocytosis on the function of isolated thyroid cells
... stimulatory effect of microbead-induced phagocytosis on phospholipogenesis only. These studies indicate that in isolated thyroid cells the phagocytotic process, per se, may alter activity of the membrane-bound ...
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Tailored design of NKT-stimulatory glycolipids for polarization of immune responses
... Natural killer T (NKT) cell is a distinct population of T lymphocytes that can rapidly release massive amount of Th1 and Th2 cytokines upon the engagement of their T cell receptor with glycolipids presented by CD1d. The ...
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T cell co stimulatory pathways in autoimmunity
... compatibility complex (MHC) molecule. However, stimulation of the TCR alone does not induce a productive T-cell response, but renders the T cells anergic. A second signal, generally provided by molecules expressed on the ...
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