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Store Operated Calcium entry

STIM and Orai1 Variants in Store-Operated Calcium Entry

STIM and Orai1 Variants in Store-Operated Calcium Entry

... (2015). Store-operated calcium entry: unveiling the calcium handling ...through store operated calcium entry and EGFR ...

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Systems Modeling of Calcium Homeostasis and Mobilization in Platelets Mediated by Ip3 and Store-Operated Calcium Entry

Systems Modeling of Calcium Homeostasis and Mobilization in Platelets Mediated by Ip3 and Store-Operated Calcium Entry

... of Calcium Homeostasis and Mobilization in Platelets Mediated by Ip3 and Store-Operated Calcium Entry Abstract Platelet aggregation is one of the body's first responses to vascular ...

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Activation of ERK1/2 by Store-Operated Calcium Entry in Rat Parotid Acinar Cells

Activation of ERK1/2 by Store-Operated Calcium Entry in Rat Parotid Acinar Cells

... 57. Chuang TY, Au LC, Wang LC, Ho LT, Yang DM, et al. (2012) Potential effect of resistin on the ET-1-increased reactions of blood pressure in rats and Ca 2+ signaling in vascular smooth muscle cells. J Cell Physiol 227: ...

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FGF2 promotes metastasis of uveal melanoma cells via store-operated calcium entry

FGF2 promotes metastasis of uveal melanoma cells via store-operated calcium entry

... intracellular calcium concentration and expression of ORAI1 and STIM1 – two key regulatory proteins of store-operated calcium entry ...

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Oxidative Stress-Induced STIM2 Cysteine Modifications Suppress Store-Operated Calcium Entry.

Oxidative Stress-Induced STIM2 Cysteine Modifications Suppress Store-Operated Calcium Entry.

... Store-operated calcium entry (SOCE) through STIM-gated ORAI channels governs vital cellular ...this calcium-redox interplay and the functional outcomes are not fully ...and ...

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Activation of the Endoplasmic Reticulum Calcium Sensor STIM1 and Store-Operated Calcium Entry by Rotavirus Requires NSP4 Viroporin Activity

Activation of the Endoplasmic Reticulum Calcium Sensor STIM1 and Store-Operated Calcium Entry by Rotavirus Requires NSP4 Viroporin Activity

... ER calcium, which ultimately leads to calcium ...ER calcium activates store-operated calcium entry (SOCE) through activation of the ER calcium sensor stromal ...

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The Potential Role of Store-Operated Calcium Entry (SOCE) Pathways in the Pathophysiology of Epilepsy and Migraine-Like Headaches in Patients with Neurocysticercosis

The Potential Role of Store-Operated Calcium Entry (SOCE) Pathways in the Pathophysiology of Epilepsy and Migraine-Like Headaches in Patients with Neurocysticercosis

... the store-operated calcium entry (SOCE) pathways are involved in the regulation of the intracellular ionic equilibrium and are determinants of the neuronal excitability ...

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Hepatitis B virus PreS2-mutant large surface antigen activates store-operated calcium entry and promotes chromosome instability

Hepatitis B virus PreS2-mutant large surface antigen activates store-operated calcium entry and promotes chromosome instability

... activates store-operated calcium entry and promotes chromosome instability Tim Ting-Chung Yen 1 , Anderson Yang 1 , Wen-Tai Chiu 2,3 , Tian-Neng Li 1 , Lyu-Han Wang 1 , Yi-Hsuan Wu 1 , ...

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Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells

Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells

... Abstract: Calcium ions regulate a wide array of physiological functions including cell differentiation, proliferation, muscle contraction, neurotransmission, and ...+ store and cellular events that induce ...

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Store-operated calcium entry in human spermatozoa

Store-operated calcium entry in human spermatozoa

... the calcium signalling ‘toolkit’ of a cell with intricate Ca 2+ flux channels, clearance mechanisms and stores, enables control of the speed, amplitude and spatio-temporal patterning of the calcium signal ...

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Molecular composition and pharmacology of store-operated calcium entry in sensory neurons

Molecular composition and pharmacology of store-operated calcium entry in sensory neurons

... YM and Synta are pyrazole-derivative drugs that were developed as SOCE inhibitors. However, their mechanism of action remains unknown. Recent literature determined that YM can interact with other Ca 2+ handling proteins ...

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The role of the Sigma1 receptor (σ1R) in Store-operated calcium entry (SOCE) microdomains

The role of the Sigma1 receptor (σ1R) in Store-operated calcium entry (SOCE) microdomains

... by sterile alpha motif (SAM) which is required for protein-protein interaction and transmembrane domain. The cytosolic portion of STIM proteins consists of three coiled-coil domains (CC1,CC2, and CC3), inhibitory domain ...

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Phenotype-specific store-operated calcium entry and the differentiation response in neuroblastoma cells /

Phenotype-specific store-operated calcium entry and the differentiation response in neuroblastoma cells /

... 2+ entry for replenishment of depleted Ca 2+ stores (Liou 2005; Roos ...2+ store is full, STIM1 monomers are sequestered in the ER (Stathopulos ...2+ store and inactivation of SOCE, STIM1 dissociates ...

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RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry

RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry

... Keywords: ciliopathy; RPGR complex; actin cytoskeleton; endoplasmic reticulum; store-operated Ca 2+ entry Received: December 11, 2017 Accepted: April 07, 2018 Published: May 01, 2018 Copyright: ...

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Store-operated calcium entry in neural cells. A  role in Charcot-Marie-Tooth disease

Store-operated calcium entry in neural cells. A role in Charcot-Marie-Tooth disease

... the store-operated pore, and in a lesser extent, TRPC4, similar to results reported for cortical and hippocampal neurons (Gruszczynska-Biegala et ...

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FGF4 induces epithelial-mesenchymal transition by inducing store-operated calcium entry in lung adenocarcinoma

FGF4 induces epithelial-mesenchymal transition by inducing store-operated calcium entry in lung adenocarcinoma

... Once the STIM protein senses a Ca 2+ level drop in the endoplasmic reticulum, it binds with Orai channels and elicits Ca 2+ influx. This process is known as SOCE [19, 25, 26, 35]. In this study, we observed that the ...

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Role of Dicer Enzyme in the Regulation of Store Operated Calcium Entry (SOCE) in CD4+ T Cells

Role of Dicer Enzyme in the Regulation of Store Operated Calcium Entry (SOCE) in CD4+ T Cells

... 2+ entry in activated Dicer fl/fl and Dicer Δ/Δ CD4 + T cells The increase of [Ca 2+ ]i plays a decisive role during the initial phase of T cell activation, particularly for the production of cytokines, cell ...

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Inhibition of store-operated calcium entry in microglia by helminth factors: implications for immune suppression in neurocysticercosis

Inhibition of store-operated calcium entry in microglia by helminth factors: implications for immune suppression in neurocysticercosis

... There is convincing evidence that Ca 2+ entry through SOCE channels differentially activates different down- stream signaling pathways. This is supported by our earl- ier studies showing contributions of ...

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Activation of store operated calcium entry in airway
smooth muscle cells: insight from a mathematical model

Activation of store operated calcium entry in airway smooth muscle cells: insight from a mathematical model

... Experiments of longer duration were performed to test the model predictions. Fig. 7A shows that if CPA is applied in the presence of agonist for 5 minutes, followed by CPA only for a further 10 minutes, ½Ca 2 z i still ...

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Associations Of Stim1 During Store-Operated Calcium Entry And Development Of A Novel Method For Multi-Biomolecule Patterning

Associations Of Stim1 During Store-Operated Calcium Entry And Development Of A Novel Method For Multi-Biomolecule Patterning

... Because of its capacity to produce patterns as small as 10 nm over large areas, with high-reproducibility and high-throughput capacity, imprint lithography has also found applications [r] ...

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