• No results found

stress fibers

The eukaryotic translation elongation factor 1A regulation of actin stress fibers is important for infectious RSV production

The eukaryotic translation elongation factor 1A regulation of actin stress fibers is important for infectious RSV production

... actin stress fiber formation, similar to the effect of eEF1A knock- down in HEp-2 cells ...actin stress fibers were reduced in Did B treated cells ...actin stress fiber formation and viral ...

10

Hippo pathway regulation by cell morphology and stress fibers

Hippo pathway regulation by cell morphology and stress fibers

... 2. Stress fiber promotes nuclear Yap downstream of cell ...microdomains. Stress fibers increase in proportion to the cell area ...stress fibers. The graph shows the relationship between ...

8

Requirement of novel amino acid fragments of orphan nuclear receptor TR3/Nur77 for its functions in angiogenesis

Requirement of novel amino acid fragments of orphan nuclear receptor TR3/Nur77 for its functions in angiogenesis

... actin stress fibers, cell proliferation, migration, and monolayer permeability ...actin stress fibers (Figure 3B), cell proliferation, migration and permeability, as TR3 does (Figure 3C, 3D ...

16

Bidirectional signaling between the cytoskeleton and integrins.pdf

Bidirectional signaling between the cytoskeleton and integrins.pdf

... (Cas) [86]. In one study, overexpression of wild-type PTP1B, but not a mutant that failed to bind to or dephos- phorylate Cas, revealed decreased cell spreading and decreased cell migration [87]. These cells developed ...

13

Influence of surface topography on the human epithelial cell response to micropatterned substrates with convex and concave architectures

Influence of surface topography on the human epithelial cell response to micropatterned substrates with convex and concave architectures

... had stress fibers with extended filopodia and immature focal contacts at the sidewalls and bottom corners, similar to those seen on the flat unpatterned substrate (Figure 4A and Figure ...

9

RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signal

RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signal

... of stress fibers caused by insufficient RhoA can result in reducing transcrip- tional activity and nuclear localization of YAP [19, 25, 26], which has been regarded as an anti-apoptosis pro- tein in many ...

12

Agonist stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c Src

Agonist stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c Src

... Thrombin and angiotensin II induce stress fiber formation and rearrangement of focal adhesions in VSMCs. To study the effects of thrombin and angII on VSMC cytoskeleton, cells were serum starved for 24 hours and ...

10

The de adhesive activity of matricellular proteins: is intermediate cell adhesion an adaptive state?

The de adhesive activity of matricellular proteins: is intermediate cell adhesion an adaptive state?

... fibers (Figure 1). The first stage of cell attachment involves the interaction between integrins, along with accessory receptors such as syndecans, and their ECM substrates. Binding of ECM components to integrins ...

7

The Adhesion Modulating Properties of Tenascin-W

The Adhesion Modulating Properties of Tenascin-W

... of stress fibers ...form stress fibers, and instead ac- quire the multipolar morphology described above for C2C12 cells cultured on tenascin-W ...

8

A feedback-loop extended stress fiber growth model with focal adhesion formation

A feedback-loop extended stress fiber growth model with focal adhesion formation

... of stress fibers, which affects the focal adhesion growth, thereby forming a cyclic chain of ...and stress fibers during cyclic loading ...and stress fiber growth, have been coupled by ...

35

In Situ Observation and Measurement of Actin Stress Fiber Deformation in Stretched Osteoblast like Cell

In Situ Observation and Measurement of Actin Stress Fiber Deformation in Stretched Osteoblast like Cell

... actin stress fiber dynamics under stretch application with high spatial and temporal ...actin stress fiber dynamics under uniaxial stretching ...in stress fibers was manually calculated from ...

13

RKI-1447, a Rho-kinase inhibitor causes ocular hypotension, actin stress fiber disruption and increased phagocytosis

RKI-1447, a Rho-kinase inhibitor causes ocular hypotension, actin stress fiber disruption and increased phagocytosis

... intraocular structures, especially on the corneal endothelium and the trabecular meshwork [37]. Our previous study in a porcine eye perfusion model suggested that iris pigment particles induced TM stress ...

17

Fixation methods can differentially affect ciliary protein immunolabeling

Fixation methods can differentially affect ciliary protein immunolabeling

... The effect of fixation on ciliary protein localization via immunocytochemistry can be demonstrated with the cilia-associated protein, CSPP1 [20]. CSPP1 was initially identified as a protein that localizes to centrosomes ...

17

1 An emerin LEM-domain mutation impairs cell

1 An emerin LEM-domain mutation impairs cell

... defective formation of actin stress fibers when myofibroblasts expressing emerin Δ K37 were grown 478. on a hard substrate or subjected to cyclic stretches. Thus, a decrease in the eme[r] ...

22

Mechanotransduction: use the force(s)

Mechanotransduction: use the force(s)

... ile stress fibers and remodeling of the actin fiber network [75, 102, ...the stress distribution depends mainly on the pad’s stiffness and mechanical ...

14

Mechanical and Systems Biology of Cancer.

Mechanical and Systems Biology of Cancer.

... of stress fibers and focal adhesion ...of stress fibers and adhesion bonds was investigated (88, 89), and it was found that cyclic stretch may induce cell reorientation through reduction of ...

18

CXCL16/CXCR6 chemokine signaling mediates breast cancer progression by pERK1/2-dependent mechanisms

CXCL16/CXCR6 chemokine signaling mediates breast cancer progression by pERK1/2-dependent mechanisms

... As previously reported, Rho/ROCK activation could lead to actomyosin-based contractility and actin cytoskeletal reorganization through indirectly phosphorylating cofilin and MLC, which could alter the integrity of ...

14

Endothelin  and oxytocin induced calcium signaling in cultured human myometrial cells

Endothelin and oxytocin induced calcium signaling in cultured human myometrial cells

... A Human skin fibroblasts; B human vascular smooth muscle cells; C human myometrial cells; and D, E, and F fields of myometrial cells at various stages of confluency.. "Stress fibers" are[r] ...

9

Alphaherpesviral US3 Kinase Induces Cofilin Dephosphorylation To Reorganize the Actin Cytoskeleton

Alphaherpesviral US3 Kinase Induces Cofilin Dephosphorylation To Reorganize the Actin Cytoskeleton

... T he US3 kinase is conserved among Alphaherpesvirinae. We and others have shown that this kinase induces dramatic rear- rangements of the actin cytoskeleton, including disassembly of actin stress fibers and ...

6

Cutaneous Human Papillomavirus Type 38 E7 Regulates Actin Cytoskeleton Structure for Increasing Cell Proliferation through CK2 and the Eukaryotic Elongation Factor 1A

Cutaneous Human Papillomavirus Type 38 E7 Regulates Actin Cytoskeleton Structure for Increasing Cell Proliferation through CK2 and the Eukaryotic Elongation Factor 1A

... actin stress fibers by HPV38 E7, suggesting addi- tional mechanisms for HPV38 E7 to disrupt the actin cytoskel- eton; for example, HPV38 E7 could act through a cellular partner that may play a role in actin ...

18

Show all 10000 documents...

Related subjects