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Structural and practical identifiability

Practical identifiability of the manipulator link stiffness parameters

Practical identifiability of the manipulator link stiffness parameters

... In the manipulator stiffness modeling, there are three main approaches that can be summarized as follows: the Finite Element Analysis (FEA), the Matrix Structural Analysis (MSA), and the Virtual Joint Method ...

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Input dependent structural identifiability of nonlinear systems

Input dependent structural identifiability of nonlinear systems

... once structural identifiability has been guar- anteed by taking into account the aforementioned issues (a, b, c), a full experiment definition still requires deciding on other aspects, such as the number ...

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On the practical identifiability of a two-parameter model of pulmonary gas exchange

On the practical identifiability of a two-parameter model of pulmonary gas exchange

... Methods: The model considers a shunt as well as ventilation-perfusion-mismatch to simulate a variety of pathologic pulmonary gas exchange states, i.e. different severities of pulmonary impairment. Synthetic patient data ...

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Structural identifiability in mixed effects models : two different approaches

Structural identifiability in mixed effects models : two different approaches

... with identifiability i) Structural identifiability, where assumption of perfect experimental conditions is made, ...ii) Practical identifiability, which concerns how the amount and ...

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Cell-Free Extract Data Variability Reduction in the Presence of Structural Non-Identifiability

Cell-Free Extract Data Variability Reduction in the Presence of Structural Non-Identifiability

... include correcting circuit behavior between cell strains or between in vitro and in vivo environments, or even between wind tunnels [5]. Extensions include generalizing condition 9 and CSP fixing to a prescription of how ...

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Identifiability of large nonlinear biochemical networks

Identifiability of large nonlinear biochemical networks

... that identifiability analysis is embedded in the more general problem of dynamic model building, which consists of a number of tasks with tight links among them, as shown schematically in Figure ...

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Structural identifiability and indistinguishability analyses of glucose insulin models

Structural identifiability and indistinguishability analyses of glucose insulin models

... performing structural identifiability analysis is to find out whether any unknown parameters present within the postulated model are unidentifiable from the observations available on the ...purely ...

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Identifiability of Path-Specific Effects

Identifiability of Path-Specific Effects

... in practical causal reasoning about legal, medical, and public policy domains, among ...linear structural equation models (SEM), but encountered difficulties in non-linear as well as non- parametric ...

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Structural and numerical identifiability of thermal resistances in plate fin-and-tube heat exchangers using manufacturer catalog data

Structural and numerical identifiability of thermal resistances in plate fin-and-tube heat exchangers using manufacturer catalog data

... of practical interest in coil simulation is to identify the thermal resistances on the air and liquid sides using manufacturer catalog ...the structural identifiability problem, that is, the ...

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Parameter identifiability of fundamental pharmacodynamic models

Parameter identifiability of fundamental pharmacodynamic models

... that structural identifiability is a prerequisite, but not a guarantee, for successful parameter estimation and practical parameter ...including structural identifiability as part of ...

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Structural identifiability of polynomial and rational systems

Structural identifiability of polynomial and rational systems

... of structural algebraic controllabil- ity, structural algebraic observability, and structural canonicity by a slight modification of the corresponding notions for polynomial and rational sys- tems ...

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Structural identifiability for mathematical pharmacology : models of myelosuppression

Structural identifiability for mathematical pharmacology : models of myelosuppression

... Promisingly, all four models are identifiable under certain simplifying assumptions. These simplifications, including k prol = k tr were previously arrived at by considering the steady states of the models and some ...

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Structural identifiability and indistinguishability in mixed effects models

Structural identifiability and indistinguishability in mixed effects models

... some structural identifiability issues can be found with a simple visual inspection while other identifiability issues can only be found using more sophisticated ...

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Structural identifiability of large systems biology models

Structural identifiability of large systems biology models

... 3.4. C ONCLUSIONS In this paper, we introduce an efficient method to reparameterise large structurally uniden- tifiable models. Our hybrid method starts with a numerical identifiability analysis. This analysis is ...

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Structural identifiability analysis via symmetries of differential equations

Structural identifiability analysis via symmetries of differential equations

... hence structural identifiability analysis could be ex- tended and performed on such systems with a suitable definition of the observation on such ...of structural identifiability analysis to a ...

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Structural identifiability of equivalent circuit models for Li Ion batteries

Structural identifiability of equivalent circuit models for Li Ion batteries

... Abstract: Structural identifiability is a critical aspect of modelling that has been overlooked in the vast majority of Li-ion battery modelling ...ascertain structural identifiability are ...

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An information-theoretic approach to assess practical identifiability of parametric dynamical systems

An information-theoretic approach to assess practical identifiability of parametric dynamical systems

... parameter identifiability of dynamical systems in a Bayesian setting is ...to practical identifiability of the ...evaluate identifiability proposed in the literature, the proposed approach ...

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Structural identifiability analyses of candidate models for in vitro Pitavastatin hepatic uptake

Structural identifiability analyses of candidate models for in vitro Pitavastatin hepatic uptake

... 1 Tel.: +44 024765 24309. 2 Tel.: +44 01625 512996. models are proposed to characterise the uptake process. In order to perform parameter estimation and compare the mod- els to ascertain those most suitable for ...

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Extending existing structural identifiability analysis methods to mixed effects models

Extending existing structural identifiability analysis methods to mixed effects models

... of structural identifiability for state-space models is expanded to cover mixed-effects state-space ...the structural identifiability of mixed-effects models are ...the structural ...

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Structural Properties of Dynamic Systems Biology Models: Identifiability, Reachability, and Initial Conditions

Structural Properties of Dynamic Systems Biology Models: Identifiability, Reachability, and Initial Conditions

... 3.5.2. Finding Solutions via Optimization An alternative, generally applicable way of answering this question is by formulating it as an optimization problem. In it, the decision variables are the system states, and the ...

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