Structural biology: data collection and refinement
Adapting Federated Cyberinfrastructure for Shared Data Collection Facilities in Structural Biology
... experimental data in structural biology is generally unmaintained and inaccessible to the ...this data, which forms the basis for each macromolecular structure discovered by this field, must ...
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SCIENTIFIC DATA VISUALIZATION AND DIGITAL IMAGE PROCESSING FOR STRUCTURAL BIOLOGY
... of symmetry are considered at this stage: the crystallographic symmetry, independent of the molecules under study, and the non-crystallographic symmetry, occurring within a molecule itself. In order to determine the ...
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X-Ray structure re-refinement. Combining old data with new methods for better structural bioinformatics.
... like refinement software, those programs and practices are subject to continuing developments and improvements, especially in view of the current interest and efforts towards better understanding radiation damage ...
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Structural Biology of the Arterivirus nsp11 Endoribonucleases
... Crystallization and data collection. Initial crystal screening was performed at 18°C and 4°C using the sitting-drop vapor diffusion method, in which 1 l of protein solution was mixed with 1 l of reservoir ...
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Collection of data and information on biology and control of vectors of Xylella fastidiosa
... whose biology/ecology/phenology is very well characterized with respect to host plant preference, life cycle and population dynamics, fecundity, flight dispersal, feeding behaviour and ...and data on host ...
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Collection of Data for Fishery Biology Studies and Fish Stock Assessment
... the data are used to provide advice on the sustainable management of fish stocks, upon which the entire fishing industry ...of data collected and used in fisheries ...fishery data. The ...
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Human motion data refinement unitizing structural sparsity and spatial-temporal information
... motion data still always contains noise and outliers, which highlights the need for the essential motion refinement ...a data-driven-based human motion refinement approach by exploiting the structural ...
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IPFQR Program: Non-Measure Data Collection and Structural Measures
... The facility most commonly used paper documents or other forms of information exchange (for example, email) not involving the transfer of health information using EHR technology at [r] ...
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Bernal and the genesis of structural biology
... molecular biology by means of which the protein of interest and its variants can be produced and purified rapidly and in quantities large enough for crystallographic ...
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Artificial Intelligence in Structural Biology
... We constantly need better and faster algorithms for integrating growing amount of data. The amount of data (genomic and structural) grows faster than our computational resources[r] ...
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Structural Refinement of the OpcA Adhesin Using Molecular Dynamics
... INTRODUCTION It is hard to conceive of modern cell biology in the absence of x-ray crystallography. The advent of this method brought about atomic-detail structures of biomolecules, allowing the mechanisms of ...
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Integrating sequence and structural biology with DAS
... biological data objects with stable identifiers which are targets for ...the data provided for the reference ...the data. Biological sequence data is dynamic: sequences change as new sequence ...
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Development and Applications of Infrared Structural Biology
... experimental data on hydrogen-bonding interactions of tyrosine has revealed that tyrosine as hydrogen-bond donor is almost twice as often as hydrogen-bond ...the data implies that ...
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Structural biology of presenilin 1 complexes
... recent models. This bi-lobed model was carefully vali- dated by multiple independent methods and has since been further confirmed by higher resolution cryo-EM data. The head domain of the bi-lobed shape contains ...
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Structural biology of induced conformational changes
... shaped Ec domain are shown in grey, the linker domain in green and the C-terminal acidic tail in blue Ec domain and the other En domain near the Ec C-terminal end. It has been shown before that GTP hydrolysis is required ...
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Mass spectrometry guided structural biology
... and structural properties of the CSNAP subunit are similar to those of DSS1, a subunit of the related 19S lid proteasome complex (sequence simi- larity of 26% and identity of 18%) [ 21 ...MS data ...
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Template Based Modeling and Structural Refinement of Protein-Protein Interactions.
... 82 5. CHAPTER 5. Conclusions Predicting the structure and function of proteins from sequence is a forefront problem in computational biology. Over the last few years there have been many advances for predicting ...
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Part of the Biochemistry, Biophysics, and Structural Biology Commons, and the Cancer Biology Commons
... CHAPTER IV ISOLATION OF DNA FROM ARCHIVAL MATERIAL Background Much o f the early work to characterize the relationship between K -ras and colorectal cancer (CRC) was done with very small sample numbers of fresh tissue or ...
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Part of the Biophysics Commons, Molecular Biology Commons, and the Structural Biology Commons
... A 100 ns atomistic simulation was performed for each of the six systems described in Table II.1 and data were collected. Each system was visually inspected and, overall, the protein appears to be stable in the ...
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Data integration in systems biology: characterization of biological phenomena from structural and functional information
... Our Proposal 3 Main Keys Network Topology Incorporation Geographic Small-World Scale-Free Random Data Integration Genomics Transcriptomics Proteomics Metabolomics Other Omics System Dyna[r] ...
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