STZ-induced diabetes
ANTI-DIABETIC ACTIVITY OF Pisonia grandis R.Br. LEAVES AGAINST STREPTOZOTOCIN (STZ) INDUCED DIABETES MELLITUS IN RATS
... Pisonia grandis R. Br. (henceforth Pg) leaves is commonly known as “Nachukottai keerai”. The leaf pharmacologically studied for its anti-inflammatory, wound healing, diuretic, analgesic, filariasis, dysentery and ...
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ANTIOXIDANT AND ANTIGLYCATION PROPERTIES OF GYMNEMA SYLVESTRE IN STREPTOZOTOCIN INDUCED DIABETIC RATS
... against STZ- induced diabetes in Albino rats (45 mg/kg body weight ) and was compared with standard hypoglycemic drug, glibenclamide ...Gs, STZ- diabetic control, Diabetic + Gs and Diabetic + ...
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Original Article Inhibitory effect of fucoidan on hypoglycemia in diabetes mellitus anim
... Fucoidan resembles heparin structurally and is a sulfated glycosaminoglycan which exhibits antithrombotic effects in vitro [1, 3]. Fucoidan has been shown to act as a potent anti-prolifer- ative agent against smooth ...
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Effect of Recombinant α1-Antitrypsin Fc-Fused (AAT-Fc) Protein on the Inhibition of Inflammatory Cytokine Production and Streptozotocin-Induced Diabetes
... the STZ-induced diabetic mouse ...in STZ- induced diabetic ...of STZ was injected twice (on d 1 and 3) to induce diabetes, and blood glucose levels were monitored (Figure ...of ...
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Caffeic acid phenethyl amide improves glucose homeostasis and attenuates the progression of vascular dysfunction in Streptozotocin-induced diabetic rats
... chronic diabetes has been in- duced in animal models, such as by chemical, surgical, and genetic manipulation ...induce diabetes and has been useful for the study of multiple aspects of the disease ...in ...
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Effects of Oxidative Stress Induced By Streptozotocin on the Morphology and Trace Minerals of The Testes of Diabetic Wistar Rats
... that STZ-induced diabetes caused 2 major alterations in Leydig cell: (a) a decrease in total Leydig cell number, and (b) an impairment in cell function, as a result of oxidative stress (as shown by ...
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Association Between LncRNA NONRATT021972 and TNF αin Diabetes
... LncRNA NONRATT021972 siRNA Decreased TNF-α in Diabetic Rats STZ-induced diabetes models were successfully established in SD adult male rats.. Further NONRA siRNA decreased blood glucose [r] ...
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Erythropoietin ameliorates hyperglycemia in type 1-like diabetic rats
... Notes: changes in glUT4 expression (A) or phosphorylated aMPK (p-aMPK) (B) in rats with sTZ-induced diabetes are shown as “sTZ” for comparison with the changes in normal rats, “normal”. in ...
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Effect of vitamin D on aortic remodeling in streptozotocin-induced diabetes
... Endothelial dysfunction, characterised by impaired production of nitric oxide (NO), plays an important role in the development of diabetic vascular complications [33]. Several studies have indicated that the impairment ...
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Journal of Applied Pharmaceutical Science
... with STZ-induced diabetes in a period of 21 days, caused no change in physiological parameters (water consumption, feed and urine volume) in biochemical markers (total cholesterol, and ...
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Effects of streptozotocin-induced diabetes on the pharmacology of rat conduit and resistance intrapulmonary arteries
... in diabetes is thought to be peripheral vasoconstriction [4] mediated, at least in part, by endothelial dysfunction [5,6] and enhanced smooth muscle contractility ...of diabetes, induced by strep- ...
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<p>Protein Arginine Methyltransferase 4 Regulates Adipose Tissue Lipolysis in Type 1 Diabetic Mice</p>
... Notes: (A–D) Lipolysis was tested in mice with streptozotocin (STZ)-induced diabetes and in control mice. The gross morphology of the fat pads (A) and the tissue weights (B) of the inguinal white ...
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Effect of C-peptide Alone or in Combination with Nicotinamide on Glucose and Insulin Levels in StreptozotocinNicotinamide-Induced Type 2 Diabetic Mice
... in STZ–NA-induced diabetic mice significantly decreased serum insulin, blood glucose, and FIRI compared to control and type 2 diabetic ...on diabetes-induced complications in kidneys, central ...
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ANTIDIABETIC POTENTIAL OF WHOLE PLANT OF PHYLLANTHUS NIRURI
... (IDF), diabetes has affected 382 million people in 2013 and its incidence is rapidly increasing and expected to affect about 600 million by the year 2035 with the majority of type 2 diabetes ...of ...
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Metabolomic analysis of rat serum in streptozotocin-induced diabetes and after treatment with oral triethylenetetramine (TETA)
... the STZ- induced rat model of DM and compare these changes to metabolic changes observed in published research in rela- tion to other animal models of DM and (ii) to investigate the metabolic response to ...
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ENHANCED GLYCEMIC CONTROL, PANCREAS PROTECTIVE, MODULATED CARBOHYDRATE METABOLIC ENZYME ACTIVITIES BY ZINGERONE IN STREPTOZOTOCIN INDUCED DIABETIC RATS
... of diabetes was 382 million in 2013 and is expected to rise to 592 million by ...combating diabetes through the utilization of herbal remedies due to their natural origin and ...
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Effect of Cichorium intybus L. on the expression of hepatic NF-κB and IKKβ and serum TNF-α in STZ− and STZ+ niacinamide-induced diabetes in rats
... Cichorium intybus L. (Chicory or Kasni) has been used in traditional medicine since the 17th century to treat digestive and hepatic disorders, as well as diabetes and inflammation. Modern research has been able to ...
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Comparative vascular responses three months after paclitaxel and everolimus-eluting stent implantation in streptozotocin-induced diabetic porcine coronary arteries
... following diabetes induction, stents were implanted and randomized to the left anterior descend- ing (LAD), left circumflex (LCX), or right coronary arteries (RCA) (one stent deployed per ...
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MINOCYCLINE DECREASES ACETYLCHOLINESTRASE ACTIVITY IN INTRA CEREBROVENTRICULAR STREPTOZOTOCIN INFUSED RATS
... glucopyranose, STZ) is an antibiotic derived from the soil bacteria Streptomyces achromogenes 6 and is oftenly used to induce diabetes mellitus in experimental animals through its toxic effects on ...
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Histological study on the effect of aqueous extract of citron leaf on pancreas of hyperglycemic wistar rats
... The histological findings showed that hyperglycemic group (Figure 4B and 5B) islet reduced with paucity of cells and presence of fibrotic tissue due to the STZ given to these group which was taken up by β cells, ...
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