Sulfate binding
Adaptation of Tick-Borne Encephalitis Virus to BHK-21 Cells Results in the Formation of Multiple Heparan Sulfate Binding Sites in the Envelope Protein and Attenuation In Vivo
... specific binding sites that can serve to perform defined biological functions ...GAG binding of viruses in their natural hosts remains rather speculative, there is solid evidence from a number ...
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Impact of Heparan Sulfate Binding on Transduction of Retina by Recombinant Adeno-Associated Virus Vectors
... Heparin binding assay and electron micrographs of various AAV2-based recombinant vectors containing tyrosine-to-phenylalanine and/or threonine- to-valine ...heparin binding elution profiles of AAV2 ...
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Heparan Sulfate Binding Can Contribute to the Neurovirulence of Neuroadapted and Nonneuroadapted Sindbis Viruses
... heparan sulfate (HS) ...HS binding pheno- type, most SB strains do not cause fatal disease in adult mice, whether inoculated subcutaneously ...HS binding in order to exhibit virulence for adult mice ...
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Heparan Sulfate Binding Promotes Accumulation of Intravitreally Delivered Adeno-associated Viral Vectors at the Retina for Enhanced Transduction but Weakly Influences Tropism
... HSPG binding is met with a reduction in IVit ...ILM binding once the vector has penetrated the ...ture, binding to the ILM can be used to accumulate vectors at the retina for ...
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Symmetry-Related Clustering of Positive Charges Is a Common Mechanism for Heparan Sulfate Binding in Enteroviruses
... HSPG binding from sequence alone is compli- cated by our results on ...HSPG binding in our E6 isolates. HSPG binding in isolates studied by Goodfellow et ...
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Efficient infection of cells in culture by type O foot-and-mouth disease virus requires binding to cell surface heparan sulfate.
... integrin binding site, type O strains of FMDV share with natural ligands of a v b 3 ...that binding to the cellular form of this sulfated glycan, heparan sulfate, is required for efficient infection ...
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Identification of Positively Charged Residues in Enterovirus 71 Capsid Protein VP1 Essential for Production of Infectious Particles
... heparan sulfate binding sites ...heparan sulfate binding, leading to a defective (mutants K242A and K244A) or lethal (mutant R166A) phenotype; therefore, another possibility for compensa- tory ...
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Control of binding and movement of fibroblast growth factors by heparan sulfate in extracellular matrix
... possible binding sites (Duchesne et al., 2012). Moreover, these heparan sulfate-binding proteins also have very extensive networks of protein-protein interactions (Ori et ...free binding sites ...
214
PubMedCentral-PMC5450942.pdf
... Heparan sulfate was less potent (Figure 7a, black bars), but the inhibitory effect was enhanced through 3-O-sulfation, in particular by Hs3st2 (Figure 7a, blue ...heparan sulfate preparations with heparin ...
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PubMedCentral-PMC4934739.pdf
... glycan binding and subsequent tissue ...SIA binding site(s), the structure of the AAV1-SIA complex was determined by X-ray crystallography to ...heparan sulfate binding serotype, followed by ...
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Sulfated glycofuranans as inhibitors of melanoma lung metastasis
... Natural potysaccharide derivatives (i.e., a xylan sulfate and a curdlan sulfate) also inhibited heparin binding to B16-BL6 cell lysate. In general, sulfated polysacchar[r] ...
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Lipoprotein lipase enhances binding of lipoproteins to heparan sulfate on cell surfaces and extracellular matrix
... enhanced binding by ...the binding of lipoproteins to heparan sulfate deficient mutant Chinese hamster ovary cells while it promotes binding to wild type cells that is abolished after ...
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Binding of thrombin to subendothelial extracellular matrix Protection and expression of functional properties
... the binding was independent of its catalytic ...thrombin binding to ECM, indicating that the binding site may reside in the vicinity of "loop B" ...dermatan sulfate in the ECM, as ...
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The Binding of Androsterone Sulfate, Etiocholanolone Sulfate, and Dehydroisoandrosterone Sulfate by Human Plasma Protein
... The binding of androsterone sulfate A-S, etiocholanolone sulfate E-S, and dehydroisoandrosterone sulfate D-S to human plasma, serum, and two albumin preparations Tritiated steroid plus a[r] ...
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Herpesvirus-induced cell fusion that is dependent on cell surface heparan sulfate or soluble heparin.
... Glycoprotein C-independent binding of herpes simplex virus 1 to cells depends on the presence of cell surface heparan sulfate and virion glycoprotein B.. Virol., in press.[r] ...
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The Binding of Cations by Chondroitin Sulfate
... In fact, if the activity coeffinow possible to calculate the activity coefficients of the sodium inside the bag, y Na+i, in the presence cients are calculated using the free sodium ion i[r] ...
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Organosulfates in atmospheric aerosol: synthesis and quantitative analysis of PM2.5 from Xi'an, northwestern China
... phenyl sulfate, 0.96 min for benzyl sulfate, ...hydroxyacetone sulfate and 5.78 min for glycolic acid sulfate, ...phenyl sulfate and hydroxyacetone sulfate when analyzing the ...
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Glycosaminoglycan Binding Properties of Natural Venezuelan Equine Encephalitis Virus Isolates
... in binding to cell surface glycosaminoglycans (GAGs) may mediate VEE ...the binding of natural enzootic and epizootic VEEV isolates to Chinese hamster ovary (CHO) cells expressing normal, high levels of ...
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Herpesviruses and heparan sulfate: an intimate relationship in aid of viral entry
... for binding to heparin or heparan ...for binding to heparin and heparan sulfate and for gB-mediated binding of virus to cells, but not for other aspects of gB function in viral entry ...
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Proposed heparin binding site in antithrombin based on arginine 47 A new variant Rouen II, 47 Arg to Ser
... heparin binding site in antithrombin and that it forms part of a proposed positively charged linear site (to which heparin binds) that stretches across the surface of the molecule from the A to the D ...
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