Sulfur Mustard (SM)
Evaluation of mRNA Expression Levels of TNFα, TNFR1 and IL1β in Lung Tissue 20 Years after Sulfur-mustard Exposure
... to sulfur mustard (SM) gas, there are many exposed subjects who are still suffering from delayed pulmonary ...of SM-exposed subjects and compared them with control (non-exposed) ...
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Evaluation of the LTBP1 and Smad6 Genes Expression in Lung Tissue of Sulfur Mustard-exposed Individuals with Long-term Pulmonary Complications
... Sulfur mustard (SM) exposure injures different organs such as the lungs and leads toshortand long term complications Transforming growth factor beta (TGF-β) has the main role in altering fibroblast ...
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The therapeutic effects of bone marrow-derived mesenchymal stromal cells in the acute lung injury induced by sulfur mustard
... Sulfur mustard (2,2-dichlorodiethyl sulfide, SM), a highly toxic chemical warfare agent, was first used in World War I in 1917, causing the injury or death of thousands of vic- tims ...storage, ...
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Original Article Changes in oxidative stress indices in sulfur mustard (1LD
... Objective: Sulfur mustard (SM) is an important chemical warfare ...underlying SM toxicity have not been completely ...in SM toxicity. In the current study, an animal model of SM ...
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Original Article Downregulation of miR-210 promotes sulfur mustard-induced skin wound healing
... Sulfur mustard (SM; 2,2-dichlorodiethyl sulfide) has been classified as an extremely toxic chem- ical warfare agent since its first use in World War I, remaining a main threat even today for both ...
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Plasma proteomic profile of sulfur mustard exposed lung diseases patients using 2-dimensional gel electrophoresis
... Sulfur mustard is a chemical warfare agent that remains a threat to human ...lethality, SM causes debilitating effects that can leave an exposed individual incapacitated for days, months, or ...
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The injury progression of T lymphocytes in a mouse model with subcutaneous injection of a high dose of sulfur mustard
... the SM exposure, the severely affected victims of the Iran-Iraq war had a lower CD3 + CD4 + level and higher CD3 + CD8 + level in plasma compared to normal controls ...after sulfur mustard gas ...
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Stenger, Bernhard (2018): Transient receptor potential A1 channels and their role in the cytotoxicity of sulfur mustard. Dissertation, LMU München: Medizinische Fakultät
... initial sulfur mustard (SM, bis(2-chlorethyl)sulfide, CAS- ...named SM, by the Belgian-French scientist César-Mansuète Despretz in 1822 ...large-scale SM production process that allowed ...
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Cleft Palate induced by Sulfur Mustard in mice fetus
... Sulfur Mustard (SM) is a chemical warfare agent which was widely used in the World War I and more recently during Gulf war in the early ...1980s'. SM is a strong alkylating agent with known ...
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Sulfur mustard induces expression of metallothionein-1A in human airway epithelial cells
... sulfur mustard-exposed patients and demonstrated that IL-8, IL-1 β , IL-6, IL-12, and tumor necrosis factor alpha levels in sulfur mustard-injured patients were all significantly higher than ...
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Childhood physical abnormalities following paternal exposure to sulfur mustard gas in Iran: a case-control study
... We began this study in 2004, about 17 years after the che- mical attack in Sardasht. We followed children up to March 2009. Sardasht is a western Iranian city that was chemically bombarded with sulfur ...
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Loss of expression of TGF-βs and their receptors in chronic skin lesions induced by sulfur mustard as compared with chronic contact dermatitis patients
... It is well known that regulatory T lymphocytes pro- duce TGF- b and that these cells may also prepare IL-10, which, like TGF- b , has immunosuppressive effects [18]. In agreement with this fact, an interesting study has ...
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Bcl-2 Protein Expression in Pulmonary Specimens of Sulfur Mustard Victims
... patients. Considering the results of this study and their comparison with other studies in the field of pulmonary fibrosis, changes in the percentage of different types of cells in lung specimens of victims was similar ...
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THE PROTECTIVE EFFECT OF INDOMETHACINE ON SULFUR MUSTARD-INDUCED OCULAR DAMAGE IN THE RABBIT EYE
... by sulfur mustard (HD) alone, lOP was increased after 30 ...by sulfur mustard and indomethacine, lOP decreased after 20 min utes and this level was maintained for the whole time of the ...
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CD4/CD8 ratio and cytokine levels of the BAL fluid in patients with bronchiectasis caused by sulfur mustard gas inhalation
... from sulfur mustard gas inhalation, known to cause antigen ...with sulfur mustard gas-induced bronchiectasis an excessive recruitment of CD4 T lymphocytes may occur in response to recurrent or ...
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EVALUATION OF 17 PATIENTS SEVERELY INJURED WITH SULFUR MUSTARD
... Sulfur mustard. or mustard gas. is an alkylating agent with a CI-CH,-CH,-S-CH,-CH,-CI formula. This di chloroethyl sulfide is vesicant and similar to other alkylating agents, undergoes strong ...
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IMMUNOHAEMATOLOGICAL AND CYTOGENETICAL STUDIES ON HUMAN POPULATION EXPOSED TO SULFUR MUSTARD
... Previous reports suggested that human exposure to sulfur mustard results in impaired immune endpoints, especially B and T helper lymphocyte numbers [17]. Low dose exposure to alkylating agents was shown to ...
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Long-term effects of sulfur mustard on civilians’ mental health 20 years after exposure (The Sardasht-Iran Cohort Study)
... Methods: This historical cohort study was conducted on 495 civilians of Sardasht and Rabat in two age matched groups, including 367 sulfur mustard exposed participants from Sardasht and 128 unexposed ...
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Effectiveness of Cytoprotective Agents on Sulfur Mustard Induced Toxicity: The In vitro Model
... The Sulfur Mustard was synthesized in Defence Research and Development Establishment, Gwalior and found to be above 99% pure by gas chromatographic ...
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Evaluation of IL 6 and IL 8 in Tear Fluid of Sulfur Mustard Gas Exposed Patients with Eye Lesions
... In summary, we found out that the eye surface changes in those who were exposed to SM (dry eye, blepharitis, corneal lesions) are in direct relation with inflammatory cytokine (IL-6, IL-8) in their tears. These ...
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