Surfactant Proteins
Surfactant Proteins and Anti-Surfactant Antibodies in Sera from Infants With Respiratory Distress Syndrome With and Without Surfactant Treatment
... Respiratory Distress Syndrome With and Without Surfactant Treatment Surfactant Proteins and Anti-Surfactant Antibodies in Sera from Infants With. Services[r] ...
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Surfactant proteins, SP-A and SP-D, in respiratory fungal infections: their role in the inflammatory response
... Surfactant proteins are produced by different cell types, and in the lung, the four types are synthesized by type II pneumocytes ...These proteins have been found in sebaceous and sweat glands, where ...
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Spatial and temporal expression of surfactant proteins in hyperoxia-induced neonatal rat lung injury
... with surfactant deficiency, oxidative stress, barotrauma, inflammation, alveolar fibrin deposition, nutrition, and genetic background ...[4-9]. Surfactant deficiency and immaturity are pivotal risk fac- ...
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Surfactant proteins A and D inhibit the growth of Gram negative bacteria by increasing membrane permeability
... collectins, surfactant proteins A (SP-A) and D (SP-D), have been reported to bind lipopolysaccharide (LPS), opsonize microorganisms, and enhance the clearance of lung ...
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Coccidioides posadasii infection alters the expression of pulmonary surfactant proteins (SP)-A and SP-D
... hand, surfactant proteins also induce phagocytosis, activation and killing of A. fumigatus conidia and C. neo- formans by alveolar macrophages and neutrophils [28,29]. In support of these findings, further ...
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The effect of interleukin-13 (IL-13) and interferon-γ (IFN-γ) on expression of surfactant proteins in adult human alveolar type II cells in vitro
... of surfactant proteins in response to IFN-g, our results differ from a previous report that showed in human fetal alveolar epithelial cells, IFN-g increased the SP-A protein level and mRNA levels, but did ...
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Expression profiles of hydrophobic surfactant proteins in children with diffuse chronic lung disease
... Here we defined the presence and characteristics of SP-B, SP-C and their processing forms in bronchoalveolar lavage fluids from children with severe chronic respiratory distress and in comparison groups of normal ...
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Novel surfactant proteins are involved in the structure and stability of foam nests from the frog Leptodactylus vastus
... of proteins with unusual primary structures and remarkable surfactant activity, named ...surfactant proteins. Analyses of the foam fluid composition showed proteins and carbohydrates ...
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Exudative Lung Injury Is Associated With Decreased Levels of Surfactant Proteins in a Rat Model of Meconium Aspiration
... aggregate surfactant phos- pholipids, this pattern suggests decreased secretion of surfactant protein from alveolar type II cells dur- ing ...of surfactant proteins to near normal with the ...
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Surfactant proteins A and D protect mice against pulmonary hypersensitivity induced by Aspergillus fumigatus antigens and allergens
... Lung surfactant proteins SP-A and SP-D can interact with the glycosylated antigens and allergens of Afu, inhibit specific IgE binding to these allergens, and block histamine release from sensitized ...
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Intravenous insulin therapy during lung resection does not affect lung function or surfactant proteins
... Our goal was to examine whether insulin affects the quality of breathing via affecting lung physiology and gene transcription. For our purposes, lung physiology was defined as blood gas levels and the genes of interest ...
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The Expression of Surfactant Proteins A and D in the Intestines and Pancreas of Murine Fetuses
... ficient surfactant proteins in the digestive tract may develop life-threatening intestinal complications, such as necrotizing enterocolitis (NEC), meconium-related ileus (MRI) [16] and focal intestinal ...
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Regulation of messenger RNAs for the hydrophobic surfactant proteins in human lung
... pulmonary surfactant proteins SP-B (8,000 D) and SP-C (4,000 D) accelerate surface film formation by surfactant ...these proteins in human fetal ...
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Ageing and smoking contribute to plasma surfactant proteins and protease imbalance with correlations to airway obstruction
... was significantly higher in middle-aged/older non-smok- ing women when compared to the men (p = 0.012). This was also a cross-sectional study, and therefore the value of these proteins in COPD will require further ...
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Influence of genetic variability at the surfactant proteins A and D in community acquired pneumonia: a prospective, observational, genetic study
... In the lung, under normal conditions, microorganisms at first encounter components of the innate immune response, particularly alveolar macrophages, dendritic cells and the lung collectins, the surfactant protein ...
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Lipopolysaccharide-induced expression of surfactant proteins A1 and A2 in human renal tubular epithelial cells
... bacteria, such as E. coli, are one of the major causes of urinary tract infection. LPS is the major component of E. coli. Thus, the severity and time course of kid- ney inflammation may depend on the amount of LPS. SP-A ...
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Surfactant Trials
... of surfactant proteins, particularly SP-B, although none of the trials that compared animal-derived surfactants to colfosceril used similar doses of ...endogenous surfactant protein ...
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Tumor necrosis factor alpha inhibits expression of pulmonary surfactant protein
... Tumor necrosis factor-alpha (TNF-alpha) decreased the expression of pulmonary surfactant proteins SP-A and SP-B in human pulmonary adenocarcinoma cell lines. The effect of TNF alpha on SP-A content and mRNA ...
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Surfactant protein Bpolymorphisms are associated with severe respiratory syncytial virus infection, but not with asthma
... hydrophilic proteins and mainly involved in the innate immune system, whereas SP-B and SP-C are hydrophobic and essential constituents of lung ...All surfactant proteins are mainly synthesised in the ...
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Pulmonary epithelial cell expression of GM CSF corrects the alveolar proteinosis in GM CSF deficient mice
... While alveolar macrophage numbers were not substantially altered in the lungs of GM2/2 mice (16), macrophages be- came increasingly foamy and laden with lipids and surfactant proteins. Marked perivascular ...
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