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Swine fever

African swine fever: an unprecedented disaster and challenge to China

African swine fever: an unprecedented disaster and challenge to China

... African swine fever (ASF), caused by African swine fever virus, is a hemorrhagic and often fatal disease of domestic pigs and wild boar, which is notifiable to the World Organization for ...

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The role of proteolytic processing of the 220kDa polyprotein of African swine fever virus and aggresomes during virion assembly

The role of proteolytic processing of the 220kDa polyprotein of African swine fever virus and aggresomes during virion assembly

... African swine fever virus (ASFV) is a large double stranded DNA virus causing a lethal haemorrhagic disease in domestic pigs. The 170kbp genome encodes 150 open reading frames and virions contain more than ...

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Substitution of Specific Cysteine Residues in the E1 Glycoprotein of Classical Swine Fever Virus Strain Brescia Affects Formation of E1-E2 Heterodimers and Alters Virulence in Swine

Substitution of Specific Cysteine Residues in the E1 Glycoprotein of Classical Swine Fever Virus Strain Brescia Affects Formation of E1-E2 Heterodimers and Alters Virulence in Swine

... Detection of E1-E2 heterodimers in infected SK6 cells. Since formation of E1-E2 heterodimers mediated by disulfide bridges is observed in lysates from cells infected with CSFV (22) and in mature CSFV virions (19), we ...

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N-Linked Glycosylation Status of Classical Swine Fever Virus Strain Brescia E2 Glycoprotein Influences Virulence in Swine

N-Linked Glycosylation Status of Classical Swine Fever Virus Strain Brescia E2 Glycoprotein Influences Virulence in Swine

... classical swine fever virus ...in swine, and ...protected swine from challenge with virulent BICv at 3 and 28 days postinfection, suggesting that glycosylation of E2 could be modified for ...

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Recombinant Antigen Targets for Serodiagnosis of African Swine Fever

Recombinant Antigen Targets for Serodiagnosis of African Swine Fever

... African swine fever (ASF) virus (ASFV) is an icosahedral cytoplasmic DNA virus that infects pigs and soft ticks of the Ornithodoros genus. This virus is the sole member of the family Asfarviridae (6). ASFV ...

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English Pig Farmers' Knowledge and Behaviour towards African Swine Fever Suspicion and Reporting

English Pig Farmers' Knowledge and Behaviour towards African Swine Fever Suspicion and Reporting

... African swine fever (ASF) is a notifiable, virulent swine disease, and is a major threat to ani- mal health and trade for many European Union (EU) ...of fever, lethargy, reduced eating and ...

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African swine fever: a global view of the current challenge

African swine fever: a global view of the current challenge

... currently available, prevention and control must be based on early detection and strict sanitary measures. Early detection should be based on rapid disease recogni- tion in the field, followed by laboratory diagnosis, ...

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The evolution of African swine fever (ASF) in Europe and our country

The evolution of African swine fever (ASF) in Europe and our country

... wild swine in Africa, such as Phacochoerus aethiopicus, but also Potamochoerus ...the fever, 1-2 days, through the secretions of the mucous membranes of the head and the of uro-genital ...(African ...

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African Swine Fever Virus Is Wrapped by the Endoplasmic Reticulum

African Swine Fever Virus Is Wrapped by the Endoplasmic Reticulum

... African swine fever (ASF) virus is a large DNA virus that shares the striking icosahedral symmetry of iridoviruses and the genomic organization of ...

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The E2 Glycoprotein of Classical Swine Fever Virus Is a Virulence Determinant in Swine

The E2 Glycoprotein of Classical Swine Fever Virus Is a Virulence Determinant in Swine

... classical swine fever virus (CSFV) virulence and host range, chimeras of the highly pathogenic Brescia strain and the attenuated vaccine strain CS were constructed and evaluated for viral virulence in ...in ...

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Biosynthesis of Classical Swine Fever Virus Nonstructural Proteins

Biosynthesis of Classical Swine Fever Virus Nonstructural Proteins

... Proteolytic processing of polyproteins is considered a crucial step in the life cycle of most positive-strand RNA viruses. An enhancement of NS2-3 processing has been described as a major difference between the ...

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Purification and properties of African swine fever virus.

Purification and properties of African swine fever virus.

... 337 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest We describe a method for African swine fever ASF virus purification based on equilibrium centrifugation in Percoll d[r] ...

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Classical swine fever virus: independent induction of protective immunity by two structural glycoproteins.

Classical swine fever virus: independent induction of protective immunity by two structural glycoproteins.

... Classical swine fever (CSF), a highly contagious infection of swine, is caused by a small enveloped RNA virus named clas- sical swine fever virus (CSFV) that is classified as belonging ...

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A Proteomic Atlas of the African Swine Fever Virus Particle

A Proteomic Atlas of the African Swine Fever Virus Particle

... ABSTRACT African swine fever virus (ASFV) is a large and complex DNA virus that causes a highly lethal swine disease for which there is no vaccine available. The ASFV particle, with an icosahedral ...

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The African Swine Fever Virus Thymidine Kinase Gene Is Required for Efficient Replication in Swine Macrophages and for Virulence in Swine

The African Swine Fever Virus Thymidine Kinase Gene Is Required for Efficient Replication in Swine Macrophages and for Virulence in Swine

... African swine fever virus (ASFV) is a large icosahedral enveloped DNA virus and is classified as the only member of a new virus family, the Asfaviridae (3, ...African swine fever (ASF) is ...

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Comparison of African Swine Fever Virus Prevalence in Nigerian Indigenous Pig, Its Hybrid and Backcross in an Environment Prone to African Swine Fever

Comparison of African Swine Fever Virus Prevalence in Nigerian Indigenous Pig, Its Hybrid and Backcross in an Environment Prone to African Swine Fever

... [7] Penrith, M.L., Thomson, G.R., Bastos, A.D.S., Phiri, O.C., Lubisi, B.A., Du Plessis, E.C., Macome, F., Pinto, F., Botha, B. and Esterhuysen, J. (2004) An Investigation into Natural Resistance to African Swine ...

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Interferon-Inducible Oligoadenylate Synthetase-Like Protein Acts as an Antiviral Effector against Classical Swine Fever Virus via the MDA5-Mediated Type I Interferon-Signaling Pathway

Interferon-Inducible Oligoadenylate Synthetase-Like Protein Acts as an Antiviral Effector against Classical Swine Fever Virus via the MDA5-Mediated Type I Interferon-Signaling Pathway

... Classical swine fever virus (CSFV) is the causative agent of classical swine fever (CSF), which poses a serious threat to the global pig ...

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Estimating the Basic Reproductive Number for African Swine Fever Using the Ukrainian Historical Epidemic of 1977

Estimating the Basic Reproductive Number for African Swine Fever Using the Ukrainian Historical Epidemic of 1977

... African swine fever is a viral contagious disease of domestic pigs and wild boar, which can be transmitted by direct contacts of susceptible animals with infectious ones or their ...

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Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target

Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target

... African swine fever virus (ASFV), an Asfivirus affecting pigs and wild boars with up to 100% case fatality rate, is currently rampaging throughout China and some other countries in ...

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A decade of research into classical swine fever marker vaccine CP7_E2alf (Suvaxyn® CSF Marker): a review of vaccine properties

A decade of research into classical swine fever marker vaccine CP7_E2alf (Suvaxyn® CSF Marker): a review of vaccine properties

... Due to its impact on animal health and pig industry, classical swine fever (CSF) is still one of the most important viral diseases of pigs. To control the disease, safe and highly efficacious live ...

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