Synthetic peptide
Approaches to Improve Chemically Defined Synthetic Peptide Vaccines
... Synthetic peptide vaccination also holds high potential for the novel field of cancer vaccination against mutation-derived neo- ...a peptide that spans the amino acid sequence on either side of the ...
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An antibody- and synthetic peptide-defined rubella virus E1 glycoprotein neutralization domain.
... To determine whether the synthetic peptides of the E1202-E1283 domain could induce a polyvalent antibody response, BALB/c mice were immunized with synthetic peptide emulsified first in c[r] ...
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Abstract: After screening nearly 1000 synthetic peptides, a synthetic peptide termed JAL-AK22
... Identification of auto-proteolysis activity of JAL-AK22 (a) time dependent 83.. analysis (b) peak collection 84.[r] ...
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Priming for rotavirus neutralizing antibodies by a VP4 protein-derived synthetic peptide.
... However, this does not rule out the possibility that some other region of the peptide, comprising the amino acid differences mentioned, could be the responsible for the priming of neutra[r] ...
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Recombinant Protein and Synthetic Peptide Based Immunoblot Test for Diagnosis of Neurocysticercosis
... One of the most well-characterized tests for diagnosing neurocysticercosis (NCC) is the enzyme-linked immunoelectrotransfer blot (EITB) assay developed at the CDC, which uses lentil lectin-bound glycoproteins (LLGP) ...
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Chagas disease specific antigens: characterization of epitopes in CRA/FRA by synthetic peptide mapping and evaluation by ELISA peptide assay
... The antigenic determinants used as binding targets for antibodies can be divided into two categories: linear or nonlinear. Linear epitopes consist of amino acid residues that are adjacent to each other in the primary ...
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Vaccine Delivery Methods into the Future
... Synthetic peptide chemistry has greatly contributed to vaccinology, where peptides (2–100 amino acids) could be synthesized and used as immunogens, in addition to synthesizing T and B cell epitopes and used ...
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Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters
... portant negative finding in this study is the absence of stimula- tion of human islets and moderately differentiated adult tumor islet-like HIT-T15 cells. This argues against a potential role of INGAP in replication of ...
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Vaccine and Monoclonal Antibody That Enhance Mouse Resistance to Candidiasis
... six synthetic peptide carriers presented on dendritic cells (DCs) for the priming and first booster immunizations and emulsified in complete Freund adjuvant (CFA) for the second booster were tested by ELISA ...
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A Novel Peptide Interfering with proBDNF-Sortilin Interaction Alleviates Chronic Inflammatory Pain
... the synthetic peptide to compete with endogenous BDNF for the binding with ...the peptide under physiological ...the peptide on attenuating the activity-dependent release of BDNF was validated ...
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Characterization of in vivo expression of the human papillomavirus type 16 E4 protein in cervical biopsy tissues
... characterize E4 protein expression in 49 paraffin-embedded cervical biopsies representing different histopathologic grades of disease, antibodies were elicited to a synthetic peptide corresponding to amino ...
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Peptide Impurities in Commercial Synthetic Peptides and Their Implications for Vaccine Trial Assessment
... Hence, peptide cross-contamination carries with it the likelihood that it would be easily mistaken as a T-cell response against the test peptide and therefore be misinter- preted as a false-positive ...
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An N terminal partial sequence of the 13 kDa Pycnopodia helianthoides sperm chemoattractant 'startrak' possesses sperm attracting activity
... the synthetic peptide suggests that the chemotactic activity of startrak depends on the sequence at the amino terminus of the native peptide, assuming that the molecular mass of 13 kDa is ...
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Immunogenicity of a Fap2 peptide mimotope of Fusobacterium nucleatum and its potential use in the diagnosis of colorectal cancer
... [20]. Synthetic peptides can excellently mimic proteins because they are exact copies of protein fragments which are re- sponsible for the protein ’ s activity ...[21]. Synthetic peptide immunogens ...
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Synthetic Long Peptide Derived from Mycobacterium tuberculosis Latency Antigen Rv1733c Protects against Tuberculosis
... FIG 2 (A) Rv1733c p57-84/CpG immunization of HLA-DR3 tg mice. Splenocytes derived from mice immunized with SLP Rv1733c p57-84 in CpG were stimulated in vitro with equimolar amounts of Rv1733c p63-77 (15-mer), p61-80 ...
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Identification and Characterization of a Peptide That Specifically Binds the Human, Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody b12
... a peptide that binds specifically to MAb ...phage-displayed peptide library by using immunoglobulin G1 b12 as the selecting ...The peptide is a homodimer whose activity depends on an intact disulfide ...
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Exploring chemoselective S to N acyl transfer reactions in synthesis and chemical biology
... the synthetic potential of both inter- and intramolecular S-to-N acyl transfer process for a diverse range of ...sophisticated synthetic acyl transfer processes and in combination with ...
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Proctolin and an Endogenous Proctolin Like Peptide Enhance the Contractility of the Limulus Heart
... A peptide with chemical properties similar to synthetic proctolin is found in the Limulus central nervous system and cardiac ganglion, and this compound enhances muscle contraction in th[r] ...
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In situ tissue engineering with synthetic self-assembling peptide nanofiber scaffolds, PuraMatrix, for mucosal regeneration in the rat middle-ear
... Donor cells were prepared from four SD-Tg rats by explant culture, as previously described. The cells were cultured up to the third passage and collected after treatment with 0.05% trypsin/PBS and then detached from the ...
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Core–shell magnetic nanoparticles display synergistic antibacterial effects against <em>Pseudomonas aeruginosa</em> and <em>Staphylococcus aureus</em> when combined with cathelicidin LL-37 or selected ceragenins
... LL-37 peptide, CSA-13, CSA-131, and tested conven- tional antibiotics. With some combinations, a synergistic or partially synergistic effect was observed. Notably, no antagonistic effects were observed in any of ...
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